Exercise training reduces resting heart rate via downregulation of the funny channel HCN4 - Wikidata - awgldk - TriplyDB

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

http://www.wikidata.org/entity/Q33626667

about

Late Na(+) current and protracted electrical recovery are critical determinants of the aging myopathy Pacemaker activity of the human sinoatrial node: an update on the effects of mutations in HCN4 on the hyperpolarization-activated current CrossTalk opposing view: bradycardia in the trained athlete is attributable to a downregulation of a pacemaker channel in the sinus node.Exercise training-induced bradycardia: evidence for enhanced parasympathetic regulation without changes in intrinsic sinoatrial node function Effects of High Intensity Interval Training on Pregnant Rats, and the Placenta, Heart and Liver of Their Fetuses.Predominance of Intrinsic Mechanism of Resting Heart Rate Control and Preserved Baroreflex Sensitivity in Professional Cyclists after Competitive Training.Different Profile of mRNA Expression in Sinoatrial Node from Streptozotocin-Induced Diabetic Rat Biology of the Sinus Node and its Disease.Reduction in Kv Current Enhances the Temporal Dispersion of the Action Potential in Diabetic Myocytes: Insights From a Novel Repolarization Algorithm.Conventional management of inappropriate sinus tachycardia.HCN4, Sinus Bradycardia and Atrial Fibrillation.Exercise training bradycardia is largely explained by reduced intrinsic heart rate.Targeting miR-423-5p Reverses Exercise Training-Induced HCN4 Channel Remodeling and Sinus Bradycardia.Point:Counterpoint.Mammalian γ2 AMPK regulates intrinsic heart rate.Novel Pathways for Regulation of Sinoatrial Node Plasticity and Heart Rate.Accentuated vagal antagonism paradoxically increases ryanodine receptor calcium leak in long-term exercised Calsequestrin2 knockout mice.Lifetime regular exercise affects the incident of different arrhythmias and improves organismal health in aging female Drosophila melanogaster.Structural, Contractile and Electrophysiological Adaptations of Cardiomyocytes to Chronic Exercise.Mechanisms of atrial fibrillation in athletes: what we know and what we do not know.HCN4 pacemaker channels attenuate the parasympathetic response and stabilize the spontaneous firing of the sinoatrial node.Whether sports participation is healthy or detrimental for the individual is a matter of dosage.Rescuing cardiac automaticity in L-type Cav1.3 channelopathies and beyond.Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study.Cardiac electrophysiological adaptations in the equine athlete-Restitution analysis of electrocardiographic features.Counterpoint: Exercise training-induced bradycardia: the case for enhanced parasympathetic regulation.Characterizing the role of atrial natriuretic peptide signaling in the development of embryonic ventricular conduction system.The Association Between Endurance Training and Heart Rate Variability: The Confounding Role of Heart Rate.Potassium channels in the sinoatrial node and their role in heart rate control Disease Modifiers of Inherited Channelopathy Long QT Syndrome and Sinus Bradycardia-A Mini Review

P2860

Q27318671-E4420CA1-51FC-4EF9-9901-6766C0527A74 Q28087293-ABBCBA91-CBC1-4B6F-B838-B34861759878 Q35517646-33F56EC2-2649-4C65-B3D3-9864607B598F Q35671705-8DB17C73-EACF-4D79-A487-45996AFC6389 Q35840967-A508962D-0B3E-4F16-84DB-7020810A0A73 Q35905040-90E366BF-6567-49EC-885B-F831633AB162 Q35994650-9F66CFE4-E5A8-48EB-A9E9-BF9F124A3433 Q36458816-8E3344C8-A74A-441D-9218-B905EDC53EDE Q36714022-D632BFA1-938F-4BC8-B4B4-C5195F82925A Q38545285-E7CC5A15-87E9-4C41-A9CE-C647C0468B11 Q38546717-DDC4CF69-AF5A-4C38-B635-21176AFEA762 Q42618262-24929381-8F0D-4F5A-B706-EAF61954B6B9 Q42705132-78BBD145-4B67-4755-87B7-33C086ED658F Q45971947-0AF68FFF-5F19-43EF-8CDE-A6A70EFD42AB Q46744561-4B14DA16-EAA6-4F36-9FF2-4A1F363F8A24 Q47449820-EE6FCBB6-8ED3-46EC-B330-C910D85ACE70 Q47655479-C84E403A-C4FA-4C43-A70D-0FDADE366CCE Q47800894-7532B0E0-AA03-48EB-9534-890B8E6EABBA Q47815987-F3183650-C0CE-4002-BF57-BD4D31C01821 Q48092580-B4B81893-3EFE-4CCD-9AAF-21ADB1B86D92 Q50119961-1463B752-927D-4EA6-8655-B0CB963876E0 Q50193060-C53A7318-53A9-4811-A361-0B8D60E52146 Q51666298-2AA8C6A3-F24E-4B61-93FA-C9B5F36899D3 Q52646911-2941B121-56C3-423F-BD93-F194757D7E32 Q52664391-03022783-10FE-49AC-B8CF-E3AFCB21DDA5 Q54133037-922B82FA-BF32-4518-A312-4BD7B39BD0A4 Q54979872-C38E8C46-B3A5-473B-8AB8-3EE325C1994F Q55413866-C121EA82-C392-4346-A26C-AE4B3D1DC834 Q57288045-D0FEFECE-EB3A-41E1-99EA-B5EECAB4B443 Q57486424-62AE4483-8FDF-4806-8A2A-45E0D83399B4 Q58801873-2F14A106-5D37-4057-91AC-E01C45A3B409

P2860

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

http://www.wikidata.org/entity/Q33626667

description

2014 nî lūn-bûn

@nan

2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

@ast

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

@en

type

label

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

@ast

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

@en

prefLabel

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

@ast

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

@en

P1433

Q33626667-7BEDADA7-C7AC-44F2-B157-88F34FE9B059

P1476

Q33626667-296AB168-89E1-4889-B3F2-32B2B13175D5

P2093

Q33626667-070A40C0-A73F-4F5E-B26E-60B768BCB026

Q33626667-2A6CB57C-0044-4FD0-9405-495B051B2459

Q33626667-6101DFD6-0903-429E-BE9E-51CB57F59004

Q33626667-7224BACB-58F0-4ADF-905B-15A0B60518FA

Q33626667-78E1DE7F-1F3E-4F48-9488-48031EADDBA3

Q33626667-DB43D588-0D85-4B15-9792-5FF9CD289C8D

Q33626667-F5B04D42-93EF-40D1-B099-6B98AB09E56B

P2860

Q33626667-05DE55C3-7366-4759-9F34-7F55E779A97D

Q33626667-07D04004-81CB-4B46-9FCF-CE5CEE013251

Q33626667-07DF5761-5FD7-46D3-82F3-DFF08D6D39EC

Q33626667-0896C147-3042-4FA0-92BC-6F2152392EF5

Q33626667-0BD297FC-02DD-4BA8-B079-A0C25017D06D

Q33626667-0E51443C-3ADF-4BDB-B9F4-C9516D4FAE6D

Q33626667-168D0F9D-47CA-4153-83FE-061B96BAFC14

Q33626667-196B160F-D5ED-4A28-866D-4E6C174F809F

Q33626667-1D225FA5-8E16-44BF-80E2-D76355940B8F

Q33626667-20BF817D-E838-4780-A006-3132D44C9169

P2888

Q33626667-8149B601-A74F-418E-84E5-982E66D78CD7

P304

Q33626667-DFA763E1-9084-43EE-88CE-5F245CB9D38B

P31

Q33626667-1FBA2F9F-82CB-4667-A0DD-3ADF8EDFC7AE

P356

Q33626667-22827D70-288F-4619-B8D9-9BD0E29F8DF6

P407

Q33626667-E6314251-EAE7-45B5-9F2B-09A22BCC4978

P478

Q33626667-2E34A330-2921-41B3-97BB-51C8AD779545

P50

Q33626667-0B7C9DB6-55DF-4A9B-A0E7-32E96F5DE984

Q33626667-0C779F34-847E-47DE-9382-41E2C82B03B0

Q33626667-8A07EC6C-8726-4B0B-AA0B-EED1564C7732

Q33626667-8A26738D-A9EC-4AF6-8C80-D24EC3D40880

Q33626667-BACE09BC-85D6-4977-AE81-C63298D5BFD1

Q33626667-CBA1EEDA-249E-4F19-A12E-F8C81EE93F37

Q33626667-DC1517D9-6BBC-4773-9983-D2B1A3B75A6A

P577

Q33626667-ACE9F39D-48DF-4E53-A3E9-53BBDFB650C3

P5875

Q33626667-EF3C9C41-439C-4153-8A46-3F8BBE288E9D

P6179

Q33626667-6C04E15E-FC72-4523-B236-9DB87E289BF6

P698

Q33626667-FB9995E4-4B23-4BBD-93C7-34FBD164AB95

P932

Q33626667-165FF3EC-288E-4B83-A6A8-CCF9E04571D6

P356

P1433

Nature Communications

P1476

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

@en

P2093

Anne Berit Johnsen

http://www.w3.org/2001/XMLSchema#string

Elizabeth Cartwright

http://www.w3.org/2001/XMLSchema#string

George Hart

http://www.w3.org/2001/XMLSchema#string

Halina Dobryznski

http://www.w3.org/2001/XMLSchema#string

Joseph Yanni

http://www.w3.org/2001/XMLSchema#string

Oliver Monfredi

http://www.w3.org/2001/XMLSchema#string

Sunil Jit R J Logantha

http://www.w3.org/2001/XMLSchema#string

P2860

Electrophysiological effects of S 16257, a novel sino-atrial node modulator, on rabbit and guinea-pig cardiac preparations: comparison with UL-FS 49

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria

Method for non-invasively recording electrocardiograms in conscious mice

Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation

The heart of trained athletes: cardiac remodeling and the risks of sports, including sudden death

Differential expression of small-conductance Ca2+-activated K+ channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytes

Localization of Na+ channel isoforms at the atrioventricular junction and atrioventricular node in the rat

The cardiac pacemaker-specific channel Hcn4 is a direct transcriptional target of MEF2

Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

P2888

P304

3775

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NCOMMS4775

http://www.w3.org/2001/XMLSchema#string

P407

P478

5

http://www.w3.org/2001/XMLSchema#string

P50

Gwilym M. Morris

Annalisa Bucchi

Dario DiFrancesco

P577

2014-05-13T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

262306078

http://www.w3.org/2001/XMLSchema#string

P6179

1002012403

http://www.w3.org/2001/XMLSchema#string

P698

24825544

http://www.w3.org/2001/XMLSchema#string

P932

4024745

http://www.w3.org/2001/XMLSchema#string