Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie. - Wikidata - awgldk - TriplyDB

Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie.

Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie.

http://www.wikidata.org/entity/Q34250173

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Characterization of the human analogue of a Scrapie-responsive gene Insights into Mechanisms of Chronic Neurodegeneration Investigating the spreading and toxicity of prion-like proteins using the metazoan model organism C. elegans Efficient uptake and dissemination of scrapie prion protein by astrocytes and fibroblasts from adult hamster brain NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity.Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions.In vivo conversion of cellular prion protein to pathogenic isoforms, as monitored by conformation-specific antibodies.Effectiveness of polyene antibiotics in treatment of transmissible spongiform encephalopathy in transgenic mice expressing Syrian hamster PrP only in neurons Entry versus blockade of brain infection following oral or intraperitoneal scrapie administration: role of prion protein expression in peripheral nerves and spleen.Species-independent inhibition of abnormal prion protein (PrP) formation by a peptide containing a conserved PrP sequence.Prion protein genes and prion diseases: studies in transgenic mice.Pathogenesis of prion diseases: a progress report.A plausible function of the prion protein: conjectures and a hypothesis.Microglia and prion disease.Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer's Disease White matter involvement in sporadic Creutzfeldt-Jakob disease.Experimental treatments for human transmissible spongiform encephalopathies: is there a role for pentosan polysulfate?The intricate mechanisms of neurodegeneration in prion diseases.T cells infiltrate the brain in murine and human transmissible spongiform encephalopathies.Differences in scrapie-induced pathology of the retina and brain in transgenic mice that express hamster prion protein in neurons, astrocytes, or multiple cell types Translation of the prion protein mRNA is robust in astrocytes but does not amplify during reactive astrocytosis in the mouse brain Antiprion immunotherapy: to suppress or to stimulate?Contributions of neuronal prion protein on sleep recovery and stress response following sleep deprivation.Host Determinants of Prion Strain Diversity Independent of Prion Protein Genotype.Prion protein expression differences in microglia and astroglia influence scrapie-induced neurodegeneration in the retina and brain of transgenic mice Effect of divalent metals on the neuronal proteasomal system, prion protein ubiquitination and aggregation.Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication.Antiprion prophylaxis by gene transfer of a soluble prion antagonist.Detection and control of prion diseases in food animals.Prion proteins: a biological role beyond prion diseases.Sphingosine kinase 1/S1P receptor signaling axis controls glial proliferation in mice with Sandhoff disease.Prion protein on astrocytes or in extracellular fluid impedes neurodegeneration induced by truncated prion protein Transmission of atypical scrapie to homozygous ARQ sheep.Caenorhabditis elegans as a model system for studying non-cell-autonomous mechanisms in protein-misfolding diseases Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death Distinct patterns of spread of prion infection in brains of mice expressing anchorless or anchored forms of prion protein Prion protein and susceptibility to kainate-induced seizures: genetic pitfalls in the use of PrP knockout mice.Analysis of the hippocampal proteome in ME7 prion disease reveals a predominant astrocytic signature and highlights the brain-restricted production of clusterin in chronic neurodegeneration.Prion disease: experimental models and reality.Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

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P2860

Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie.

http://www.wikidata.org/entity/Q34250173

description

1997 nî lūn-bûn

@nan

1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի հոտեմբերին հրատարակված գիտական հոդված

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1997年の論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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name

Astrocyte-specific expression ...... usceptible to hamster scrapie.

@ast

Astrocyte-specific expression ...... usceptible to hamster scrapie.

@en

Astrocyte-specific expression of hamster prion protein

@nl

type

label

Astrocyte-specific expression ...... usceptible to hamster scrapie.

@ast

Astrocyte-specific expression ...... usceptible to hamster scrapie.

@en

Astrocyte-specific expression of hamster prion protein

@nl

prefLabel

Astrocyte-specific expression ...... usceptible to hamster scrapie.

@ast

Astrocyte-specific expression ...... usceptible to hamster scrapie.

@en

Astrocyte-specific expression of hamster prion protein

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The EMBO Journal

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Astrocyte-specific expression ...... usceptible to hamster scrapie.

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A J Raeber

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A Sailer

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B Chesebro

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C Weissmann

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J Manson

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L Mucke

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M B Oldstone

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R A Bessen

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R E Race

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S A Priola

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P2860

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Mice devoid of PrP are resistant to scrapie

Novel proteinaceous infectious particles cause scrapie

A new variant of Creutzfeldt-Jakob disease in the UK.

Molecular biology of prion diseases.

A cellular gene encodes scrapie PrP 27-30 protein.

Scrapie prion proteins are synthesized in neurons

A single hamster PrP amino acid blocks conversion to protease-resistant PrP in scrapie-infected mouse neuroblastoma cells.

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

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6057-6065

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10.1093/EMBOJ/16.20.6057

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20

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16

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13904577

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9321385

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Prion protein family

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1326289

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