Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death - Wikidata - awgldk - TriplyDB

Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death

Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death

http://www.wikidata.org/entity/Q37484906

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Cellular aspects of prion replication in vitro Efficient uptake and dissemination of scrapie prion protein by astrocytes and fibroblasts from adult hamster brain Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapie-infected mice: a possible role in pathogenesis Endogenous proteolytic cleavage of disease-associated prion protein to produce C2 fragments is strongly cell- and tissue-dependent.Recovery of small infectious PrP(res) aggregates from prion-infected cultured cells.A bovine cell line that can be infected by natural sheep scrapie prions.Prion infection of mouse neurospheres.Mammalian prions: tracking the infectious entities Prions impair bioaminergic functions through serotonin- or catecholamine-derived neurotoxins in neuronal cells.Double-Edge Sword of Sustained ROCK Activation in Prion Diseases through Neuritogenesis Defects and Prion Accumulation Prion infection of muscle cells in vitro A Neuronal Culture System to Detect Prion Synaptotoxicity.Prion strain- and species-dependent effects of antiprion molecules in primary neuronal cultures Stressing out the ER: a role of the unfolded protein response in prion-related disorders Prion propagation and toxicity occur in vitro with two-phase kinetics specific to strain and neuronal type.Diminishing apoptosis by deletion of Bax or overexpression of Bcl-2 does not protect against infectious prion toxicity in vivo.Prion replication elicits cytopathic changes in differentiated neurosphere cultures.Opposing roles of prion protein in oxidative stress- and ER stress-induced apoptotic signaling.Susceptibility of cell substrates to PrPSc infection and safety control measures related to biological and biotherapeutical products.Synaptic dysfunction in prion diseases: a trafficking problem?Human tonsil-derived follicular dendritic-like cells are refractory to human prion infection in vitro and traffic disease-associated prion protein to lysosomes.Cells and prions: a license to replicate.Analysis of the hippocampal proteome in ME7 prion disease reveals a predominant astrocytic signature and highlights the brain-restricted production of clusterin in chronic neurodegeneration.The case for involvement of spiroplasma in the pathogenesis of transmissible spongiform encephalopathies.The potential of mesenchymal stem cell in prion research.Astrocyte-to-neuron intercellular prion transfer is mediated by cell-cell contact Prion strains depend on different endocytic routes for productive infection.Expression of Heterologous PrP and Prion Propagation in RK13 Cells.Comparison of abnormal isoform of prion protein in prion-infected cell lines and primary-cultured neurons by PrPSc-specific immunostaining.Alteration of NF-kappaB activity leads to mitochondrial apoptosis after infection with pathological prion protein.The spread of prion-like proteins by lysosomes and tunneling nanotubes: Implications for neurodegenerative diseases.Rapid cell-surface prion protein conversion revealed using a novel cell system.Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells.Cell Biology Approaches to Studying Prion Diseases.Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes.Toll-like receptor-mediated immune response inhibits prion propagation.Accelerated prion replication in, but prolonged survival times of, prion-infected CXCR3-/- mice.The alpha-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo Prion protein aggregation and neurotoxicity in cortical neurons.A "dry and wet hybrid" lithography technique for multilevel replication templates: Applications to microfluidic neuron culture and two-phase global mixing.

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P2860

Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death

http://www.wikidata.org/entity/Q37484906

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 09 August 2004

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death

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Prions can infect primary cult ...... d promote neuronal cell death.

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type

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Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death

@en

Prions can infect primary cult ...... d promote neuronal cell death.

@nl

prefLabel

Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death

@en

Prions can infect primary cult ...... d promote neuronal cell death.

@nl

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PNAS.0402725101

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Proceedings of the National Academy of Sciences of the United States of America

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Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death

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Hubert Laude

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Jean-Michel Peyrin

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Sabrina Cronier

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P2860

Prion diseases of humans and animals: their causes and molecular basis

Mice devoid of PrP are resistant to scrapie

Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein

Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine prp.

Sindbis virus-induced neuronal death is both necrotic and apoptotic and is ameliorated by N-methyl-D-aspartate receptor antagonists

Pathways to neuronal injury and apoptosis in HIV-associated dementia.

Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie.

Measurement of the scrapie agent using an incubation time interval assay.

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

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12271-12276

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scholarly article

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10.1073/PNAS.0402725101

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101

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2004-08-09T00:00:00Z

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8408092

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15302929

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Prion protein family

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514468

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