Bridging the gap between structural models of nicotinic receptor superfamily ion channels and their corresponding functional states
about
The Intracellular Loop of the Glycine Receptor: It's not all about the SizeLigand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELICGating Movement of Acetylcholine Receptor Caught by Plunge-FreezingMutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystalsGating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallographyX-ray structure of the human α4β2 nicotinic receptorMolecular mechanism for the dual alcohol modulation of Cys-loop receptorsSite-directed spin labeling reveals pentameric ligand-gated ion channel gating motionsThe role of intracellular linkers in gating and desensitization of human pentameric ligand-gated ion channelsNicotinic acetylcholine receptor and the structural basis of neuromuscular transmission: insights from Torpedo postsynaptic membranesMapping heat exchange in an allosteric proteinStructure of the M2 transmembrane segment of GLIC, a prokaryotic Cys loop receptor homologue from Gloeobacter violaceus, probed by substituted cysteine accessibility.Phenylalanine in the pore of the Erwinia ligand-gated ion channel modulates picrotoxinin potency but not receptor functionMacroscopic kinetics of pentameric ligand gated ion channels: comparisons between two prokaryotic channels and one eukaryotic channel.Structural basis for alcohol modulation of a pentameric ligand-gated ion channelEngineering a prokaryotic Cys-loop receptor with a third functional domain.Allosteric regulation of pentameric ligand-gated ion channels: an emerging mechanistic perspectiveThe atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold.A chimeric prokaryotic pentameric ligand-gated channel reveals distinct pathways of activation.Gating-induced conformational rearrangement of the γ-aminobutyric acid type A receptor β-α subunit interface in the membrane-spanning domainTheory and simulation of ion conduction in the pentameric GLIC channelInhibition versus potentiation of ligand-gated ion channels can be altered by a single mutation that moves ligands between intra- and intersubunit sitesCysteine substitutions define etomidate binding and gating linkages in the α-M1 domain of γ-aminobutyric acid type A (GABAA) receptorsUsing molecular dynamics to elucidate the structural basis for function in pLGICsAn outline of desensitization in pentameric ligand-gated ion channel receptors.EPR Studies of Gating Mechanisms in Ion Channels.Molecular dissection of Cl--selective Cys-loop receptor points to components that are dispensable or essential for channel activity.Cys-loop receptor channel blockers also block GLIC.Mechanism of activation of the prokaryotic channel ELIC by propylamine: a single-channel study.Intramembrane aromatic interactions influence the lipid sensitivities of pentameric ligand-gated ion channels.Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC).Desensitization mechanism in prokaryotic ligand-gated ion channelConformational transitions underlying pore opening and desensitization in membrane-embedded Gloeobacter violaceus ligand-gated ion channel (GLIC)Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites.Chasing the open-state structure of pentameric ligand-gated ion channels.
P2860
Q26743781-C0E705B6-B38F-42CB-88AB-23F4A1497BCAQ27670592-AD814A96-27C8-4ADD-B76B-867FFEC777CCQ27670932-97935C66-55BD-4790-A00A-0CBD5CFECC7FQ27678323-A1843E95-725E-4D5E-87B1-022F11C77A83Q27680479-5373B0CA-DDC6-4BB6-A127-BC0DB2561F62Q27728171-20D51A2C-E0FA-4572-832F-40CA43AA1F61Q28484223-420BBB87-2C96-489E-9B3C-843A9A2E1B10Q28535256-CE03D5C2-3D53-4753-A910-1AD7BA8F2EBAQ33639488-E004DEF8-DE78-47A3-8D0C-634BF5B6DEBDQ34372276-576D2AFE-57B5-42B5-8CBE-8446D5A7CE15Q34568707-526ACB56-37E2-4F3B-8AD4-7677C997F378Q34800089-2220D057-92A1-4C47-89F8-3A1BF9AEC59CQ35032362-056CCFFB-C5D9-4C3A-AD52-FCF75EDE18BBQ35048943-31771AC0-7031-4E85-9FA5-8C7481265454Q35122953-C8ADBCE1-8183-4E3E-AC1E-3C3F2BCA916DQ35266466-7D560257-6B3C-46D6-A78E-65F278B992E5Q35493550-CDD1F407-FF6F-4D2A-8360-60C6F1DD28A3Q35795776-64F4A2A3-E95C-4114-BB9B-0704F6C13206Q36102224-343FD4C6-B6FB-40EE-AAF5-27F75FDC6B2AQ36201884-C062E08B-0930-4050-B4B1-B897E1503AF6Q36600215-AD0AC7B4-B0E5-4DAB-A9D7-6054D640E0EEQ37209057-235EFE1A-59FF-4CA5-8846-8BDCB226D99CQ37234043-C4EEB030-4613-4023-B738-241F388AA651Q37240694-060DA803-3B16-4A32-96BC-8AD02C1C8B21Q38039375-886B3D97-56BE-47F1-8EE8-32BDAC50CB1FQ38464421-5EE01028-59D0-423D-83F9-19D3E44545DBQ39936711-F50DC7FF-AE78-497F-A191-7C2122F97218Q39949261-24B80292-2F24-4037-A58C-8312E0967FF2Q41640531-E66DDB32-63A1-46DE-9CE3-FA532589C57FQ41675967-03FF8BD9-4546-4AA2-B92D-D3D6977E7E5EQ41903108-1BD351EF-9813-4324-8E19-127327A57EF1Q42182878-B71DDF9A-0EF7-40F8-A000-2FB76812EC39Q42404119-6A43343B-C4A7-468B-8C4B-49615FB2D1DEQ47246914-7E683964-AE33-4C2C-965F-A830CACCC3C0Q48093253-026B4526-8048-4FCB-9BD5-74B39B237FCF
P2860
Bridging the gap between structural models of nicotinic receptor superfamily ion channels and their corresponding functional states
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Bridging the gap between struc ...... orresponding functional states
@ast
Bridging the gap between struc ...... orresponding functional states
@en
Bridging the gap between struc ...... orresponding functional states
@nl
type
label
Bridging the gap between struc ...... orresponding functional states
@ast
Bridging the gap between struc ...... orresponding functional states
@en
Bridging the gap between struc ...... orresponding functional states
@nl
prefLabel
Bridging the gap between struc ...... orresponding functional states
@ast
Bridging the gap between struc ...... orresponding functional states
@en
Bridging the gap between struc ...... orresponding functional states
@nl
P2860
P1476
Bridging the gap between struc ...... orresponding functional states
@en
P2093
Claudio Grosman
Giovanni Gonzalez-Gutierrez
P2860
P304
P356
10.1016/J.JMB.2010.09.026
P407
P577
2010-09-21T00:00:00Z