Cysteine substitutions define etomidate binding and gating linkages in the α-M1 domain of γ-aminobutyric acid type A (GABAA) receptors
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Mutations at beta N265 in γ-aminobutyric acid type A receptors alter both binding affinity and efficacy of potent anestheticsA Multifaceted GABAA Receptor Modulator: Functional Properties and Mechanism of Action of the Sedative-Hypnotic and Recreational Drug Methaqualone (Quaalude)The Direct Actions of GABA, 2'-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABAA Receptors: Evidence for Receptors with Different Subunit Stoichiometries.A Cysteine Substitution Probes β3H267 Interactions with Propofol and Other Potent Anesthetics in α1β3γ2L γ-Aminobutyric Acid Type A ReceptorsMapping General Anesthetic Sites in Heteromeric γ-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes.Mutational Analysis at Intersubunit Interfaces of an Anionic Glutamate Receptor Reveals a Key Interaction Important for Channel Gating by Ivermectin.Tryptophan and Cysteine Mutations in M1 Helices of α1β3γ2L γ-Aminobutyric Acid Type A Receptors Indicate Distinct Intersubunit Sites for Four Intravenous Anesthetics and One Orphan Site.Alphaxalone Binds in Inner Transmembrane β+-α- Interfaces of α1β3γ2 γ-Aminobutyric Acid Type A Receptors.Comparison of αβδ and αβγ GABAA receptors: Allosteric modulation and identification of subunit arrangement by site-selective general anesthetics.General Anesthetic Binding Sites in Human α4β3δ γ-Aminobutyric Acid Type A Receptors (GABAARs).Analysis of γ-aminobutyric acid (GABA) type A receptor subtypes using isosteric and allosteric ligands.
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P2860
Cysteine substitutions define etomidate binding and gating linkages in the α-M1 domain of γ-aminobutyric acid type A (GABAA) receptors
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cysteine substitutions define ...... acid type A (GABAA) receptors
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Cysteine substitutions define ...... of γ-aminobutyric acid type A
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type
label
Cysteine substitutions define ...... acid type A (GABAA) receptors
@en
Cysteine substitutions define ...... of γ-aminobutyric acid type A
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prefLabel
Cysteine substitutions define ...... acid type A (GABAA) receptors
@en
Cysteine substitutions define ...... of γ-aminobutyric acid type A
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P2093
P2860
P356
P1476
Cysteine substitutions define ...... acid type A (GABAA) receptors
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P2093
David C Chiara
Deirdre S Stewart
Guo-Dong Li
Mayo Hotta
Richard W Olsen
Rooma Desai
Stuart A Forman
P2860
P304
30373-30386
P356
10.1074/JBC.M113.494583
P407
P577
2013-09-05T00:00:00Z