Hypermethylation of PTGER2 confers prostaglandin E2 resistance in fibrotic fibroblasts from humans and mice. - Wikidata - awgldk - TriplyDB

Hypermethylation of PTGER2 confers prostaglandin E2 resistance in fibrotic fibroblasts from humans and mice.

Hypermethylation of PTGER2 confers prostaglandin E2 resistance in fibrotic fibroblasts from humans and mice.

http://www.wikidata.org/entity/Q34254378

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Regulation of immune responses by prostaglandin E2 Epigenetic regulations of inflammatory cyclooxygenase-derived prostanoids: molecular basis and pathophysiological consequences Personalized medicine: applying 'omics' to lung fibrosis Beyond the genome: epigenetic mechanisms in lung remodeling Global methylation patterns in idiopathic pulmonary fibrosis Impaired E Prostanoid2 Expression and Resistance to Prostaglandin E2 in Nasal Polyp Fibroblasts from Subjects with Aspirin-Exacerbated Respiratory Disease.Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis Matrix metalloproteinase-19 is a key regulator of lung fibrosis in mice and humans Prostaglandin E2 inhibits α-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-A Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4.Following the path of CCL2 from prostaglandins to periostin in lung fibrosis Pathogenesis of idiopathic pulmonary fibrosis: review of recent findings.Lung fibroblasts from patients with idiopathic pulmonary fibrosis exhibit genome-wide differences in DNA methylation compared to fibroblasts from nonfibrotic lung Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis Plasmin overcomes resistance to prostaglandin E2 in fibrotic lung fibroblasts by reorganizing protein kinase A signaling Prostaglandin E2 and the pathogenesis of pulmonary fibrosis.Airway remodeling in murine asthma correlates with a defect in PGE2 synthesis by lung fibroblasts.Prostaglandin E2 as an inhibitory modulator of fibrogenesis in human lung allografts Epigenetics and the overhealing wound: the role of DNA methylation in fibrosis.Methylation-mediated BMPER expression in fibroblast activation in vitro and lung fibrosis in mice in vivo.Prostaglandin E₂ increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expression COX-2 expression is upregulated by DNA hypomethylation after hematopoietic stem cell transplantation.Altered DNA methylation profile in idiopathic pulmonary fibrosis.Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis Matrices of physiologic stiffness potently inactivate idiopathic pulmonary fibrosis fibroblasts.Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts.Reversal of myofibroblast differentiation by prostaglandin E(2).Epigenetics within the matrix: a neo-regulator of fibrotic disease.The role of promoter hypermethylation in fibroblast activation and fibrogenesis.Pathogenesis of aspirin-exacerbated respiratory disease and reactions.Epigenetics in immune-mediated pulmonary diseases.Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.Epigenetic control of skin and hair regeneration after wounding Epigenetic targets for novel therapies of lung diseases.Epigenetics in idiopathic pulmonary fibrosis.Dissecting fibrosis: therapeutic insights from the small-molecule toolbox.Transforming Growth Factor-β1 Increases DNA Methyltransferase 1 and 3a Expression through Distinct Post-transcriptional Mechanisms in Lung Fibroblasts.Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo.Epigenetic Therapy for the Treatment of Hypertension-Induced Cardiac Hypertrophy and Fibrosis.Lung Pericytes and Resident Fibroblasts: Busy Multitaskers.

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Hypermethylation of PTGER2 confers prostaglandin E2 resistance in fibrotic fibroblasts from humans and mice.

http://www.wikidata.org/entity/Q34254378

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Hypermethylation of PTGER2 con ...... roblasts from humans and mice.

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Hypermethylation of PTGER2 con ...... roblasts from humans and mice.

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Hypermethylation of PTGER2 con ...... roblasts from humans and mice.

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type

label

Hypermethylation of PTGER2 con ...... roblasts from humans and mice.

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Hypermethylation of PTGER2 con ...... roblasts from humans and mice.

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Hypermethylation of PTGER2 con ...... roblasts from humans and mice.

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Hypermethylation of PTGER2 con ...... roblasts from humans and mice.

@ast

Hypermethylation of PTGER2 con ...... roblasts from humans and mice.

@en

Hypermethylation of PTGER2 con ...... roblasts from humans and mice.

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The American Journal of Pathology

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Hypermethylation of PTGER2 con ...... roblasts from humans and mice.

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Aaron S Fisher

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Anne M Scruggs

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Bruce C Richardson

http://www.w3.org/2001/XMLSchema#string

Cory M Hogaboam

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Eric S White

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Steven K Huang

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P2860

CpG islands in vertebrate genomes

Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy

American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Soci

Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice

Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype

Epigenetics in cancer

The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients.

Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways.

Cloning, structural characterization, and chromosomal localization of the gene encoding the human prostaglandin E(2) receptor EP2 subtype.

Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.

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177

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Marc Peters-Golden

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2010-10-01T00:00:00Z

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47300095

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