The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation. - Wikidata - awgldk - TriplyDB

The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.

The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.

http://www.wikidata.org/entity/Q34265917

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Variant base excision repair proteins: contributors to genomic instability Microsatellite instability in colorectal cancer Human AP endonuclease suppresses DNA mismatch repair activity leading to microsatellite instability.Gut Microbiota Imbalance and Base Excision Repair Dynamics in Colon Cancer Tumor-specific microsatellite instability: do distinct mechanisms underlie the MSI-L and EMAST phenotypes?Transcriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptation Structural Basis for the Inhibition of Human Alkyladenine DNA Glycosylase (AAG) by 3,N4-Ethenocytosine-containing DNA Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase Effect of Inulin on Proteome Changes Induced by Pathogenic Lipopolysaccharide in Human Colon Regulation of Rac1 and Reactive Oxygen Species Production in Response to Infection of Gastrointestinal Epithelia Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage.Inflammation and oncogenesis: a vicious connection.The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis.Frameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase.Human base excision repair creates a bias toward -1 frameshift mutations Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel disease The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress.Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney.Inflammatory colonic carcinogenesis: a review on pathogenesis and immunosurveillance mechanisms in ulcerative colitis Substitution of active site tyrosines with tryptophan alters the free energy for nucleotide flipping by human alkyladenine DNA glycosylase.Interplay between DNA repair and inflammation, and the link to cancer Enzymatic MPG DNA repair assays for two different oxidative DNA lesions reveal associations with increased lung cancer risk Chemistry meets biology in colitis-associated carcinogenesis Naturally occurring polyphenol, morin hydrate, inhibits enzymatic activity of N-methylpurine DNA glycosylase, a DNA repair enzyme with various roles in human disease.Infection, inflammation, and gastrointestinal cancer.Tumbling down a different pathway to genetic instability.Apurinic/Apyrimidinic endonuclease 1 regulates inflammatory response in macrophages.Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability Fractionated Radiation Exposure of Rat Spinal Cords Leads to Latent Neuro-Inflammation in Brain, Cognitive Deficits, and Alterations in Apurinic Endonuclease 1.Beyond translesion synthesis: polymerase κ fidelity as a potential determinant of microsatellite stability.Base excision repair: contribution to tumorigenesis and target in anticancer treatment paradigms DNA repair is indispensable for survival after acute inflammation.Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer Accumulation of oxidatively generated DNA damage in the brain: a mechanism of neurotoxicity.N-methylpurine DNA glycosylase inhibits p53-mediated cell cycle arrest and coordinates with p53 to determine sensitivity to alkylating agents.Targeting chemokine pathways in esophageal adenocarcinoma.Mechanisms of glycosylase induced genomic instability N-methylpurine DNA glycosylase and OGG1 DNA repair activities: opposite associations with lung cancer risk.

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P2860

The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.

http://www.wikidata.org/entity/Q34265917

description

2003 nî lūn-bûn

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2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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The adaptive imbalance in base ...... ility in chronic inflammation.

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The adaptive imbalance in base ...... ility in chronic inflammation.

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The adaptive imbalance in base ...... ility in chronic inflammation.

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type

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The adaptive imbalance in base ...... ility in chronic inflammation.

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The adaptive imbalance in base ...... ility in chronic inflammation.

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The adaptive imbalance in base ...... ility in chronic inflammation.

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prefLabel

The adaptive imbalance in base ...... ility in chronic inflammation.

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The adaptive imbalance in base ...... ility in chronic inflammation.

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The adaptive imbalance in base ...... ility in chronic inflammation.

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Journal of Clinical Investigation

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The adaptive imbalance in base ...... bility in chronic inflammation

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Curtis C Harris

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Irit Zurer

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Leah E Mechanic

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Leona D Samson

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Lorne J Hofseth

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Maria Kartalou

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Meng Xu-Welliver

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Mohammed A Khan

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Olga Nikolayeva

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Richard B Roth

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P2860

Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300

Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins

Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

Human OGG1 undergoes serine phosphorylation and associates with the nuclear matrix and mitotic chromatin in vivo

Somatic frameshift mutations in the Bloom syndrome BLM gene are frequent in sporadic gastric carcinomas with microsatellite mutator phenotype

Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer

Negative regulation of the major human AP-endonuclease, a multifunctional protein

Etheno DNA-base adducts from endogenous reactive species.

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1887-1894

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10.1172/JCI200319757

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12

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112

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2003-12-01T00:00:00Z

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8956550

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14679184

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