Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation.
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Organ-on-a-Chip: New Platform for Biological AnalysisModels and methods for in vitro testing of hepatic gap junctional communicationCell sources, liver support systems and liver tissue engineering: alternatives to liver transplantationStem cell-derived hepatocytes as a predictive model for drug-induced liver injury: are we there yet?Development of a pneumatically driven active cover lid for multi-well microplates for use in perfusion three-dimensional cell culturePersistent hepatitis C virus infection in microscale primary human hepatocyte culturesPluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineeringInsights into CYP2B6-mediated drug-drug interactionsAMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell lineLabel-free evaluation of hepatic microvesicular steatosis with multimodal coherent anti-Stokes Raman scattering microscopyCross-species gene expression analysis of species specific differences in the preclinical assessment of pharmaceutical compoundsDrug-botanical interactions: a review of the laboratory, animal, and human data for 8 common botanicals.A comparison of whole genome gene expression profiles of HepaRG cells and HepG2 cells to primary human hepatocytes and human liver tissues.Liver tissue engineering in the evaluation of drug safety.Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues.Assessment of compound hepatotoxicity using human plateable cryopreserved hepatocytes in a 1536-well-plate format.In vitro platforms for evaluating liver toxicity.Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation.Evaluation of an in vitro toxicogenetic mouse model for hepatotoxicitySandwich-cultured hepatocytes: utility for in vitro exploration of hepatobiliary drug disposition and drug-induced hepatotoxicity.Pregnane X receptor and drug-induced liver injury.Differential activation of pregnane X receptor and constitutive androstane receptor by buprenorphine in primary human hepatocytes and HepG2 cells.Zebrafish as model organisms for studying drug-induced liver injuryReceptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.Similarities and differences in the expression of drug-metabolizing enzymes between human hepatic cell lines and primary human hepatocytes.CYP2B6: new insights into a historically overlooked cytochrome P450 isozymeMechanisms underlying differences in systemic exposure of structurally similar active metabolites: comparison of two preclinical hepatic models.Sandwich-cultured hepatocytes: an in vitro model to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity.Predicting inductive drug-drug interactions.Interactions of herbs with cytochrome P450.Interactions between the cytochrome P450 system and the second-generation antipsychotics.Chimeric mice with humanized liver: tools for the study of drug metabolism, excretion, and toxicityThe conduct of in vitro and in vivo drug-drug interaction studies: a PhRMA perspective.Quantitative high-throughput identification of drugs as modulators of human constitutive androstane receptor.Potential and Challenges of Induced Pluripotent Stem Cells in Liver Diseases Treatment.Rhein Elicits In Vitro Cytotoxicity in Primary Human Liver HL-7702 Cells by Inducing Apoptosis through Mitochondria-Mediated Pathway.Food-drug interactions via human cytochrome P450 3A (CYP3A).New technologies and screening strategies for hepatotoxicity: use of in vitro models.A clinical study to assess CYP1A2 and CYP3A4 induction by AZD7325, a selective GABA(A) receptor modulator - an in vitro and in vivo comparison.Organotypic liver culture models: meeting current challenges in toxicity testing.
P2860
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P2860
Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Human hepatocyte culture syste ...... 450 expression and regulation.
@ast
Human hepatocyte culture syste ...... 450 expression and regulation.
@en
Human hepatocyte culture syste ...... 450 expression and regulation.
@nl
type
label
Human hepatocyte culture syste ...... 450 expression and regulation.
@ast
Human hepatocyte culture syste ...... 450 expression and regulation.
@en
Human hepatocyte culture syste ...... 450 expression and regulation.
@nl
prefLabel
Human hepatocyte culture syste ...... 450 expression and regulation.
@ast
Human hepatocyte culture syste ...... 450 expression and regulation.
@en
Human hepatocyte culture syste ...... 450 expression and regulation.
@nl
P1476
Human hepatocyte culture syste ...... P450 expression and regulation
@en
P2093
LeCluyse EL
P304
P356
10.1016/S0928-0987(01)00135-X
P407
P577
2001-07-01T00:00:00Z