Network organization of the huntingtin proteomic interactome in mammalian brain.
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The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's diseaseSubcellular Clearance and Accumulation of Huntington Disease Protein: A Mini-ReviewGenetic, transcriptomic, and epigenetic studies of HIV-associated neurocognitive disorderHuntington's disease: underlying molecular mechanisms and emerging conceptsProtein-protein interaction networks: probing disease mechanisms using model systemsN17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic miceHuntingtin Is Required for Epithelial Polarity through RAB11A-Mediated Apical Trafficking of PAR3-aPKCHuntingtin's function in axonal transport is conserved in Drosophila melanogasterIdentification of Coq11, a new coenzyme Q biosynthetic protein in the CoQ-synthome in Saccharomyces cerevisiaeIntravitreal administration of HA-1077, a ROCK inhibitor, improves retinal function in a mouse model of huntington diseaseSorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's diseaseIs Huntingtin Dispensable in the Adult Brain?Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis.N-terminal Huntingtin Knock-In Mice: Implications of Removing the N-terminal Region of Huntingtin for Therapy.Huntingtin is required for normal excitatory synapse development in cortical and striatal circuitsSynaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms.Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's diseaseMolecular interaction networks in the analyses of sequence variation and proteomics data.Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia.Huntingtin is required for ER-to-Golgi transport and for secretory vesicle fusion at the plasma membrane.Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.Dynamics of social network structure for Alzheimer and Lymphoma scientific communities.Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo.A Rich-Club Organization in Brain Ischemia Protein Interaction NetworkSystems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington's DiseasePolyglutamine Tract Expansion Increases S-Nitrosylation of Huntingtin and Ataxin-1.Pulsed Azidohomoalanine Labeling in Mammals (PALM) Detects Changes in Liver-Specific LKB1 Knockout Mice.Proteome profiling in IL-1β and VEGF-activated human umbilical vein endothelial cells delineates the interlink between inflammation and angiogenesis.Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders.Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis.VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington's diseaseBidirectional control of postsynaptic density-95 (PSD-95) clustering by Huntingtin.A large scale Huntingtin protein interaction network implicates Rho GTPase signaling pathways in Huntington disease.Huntingtin regulates mammary stem cell division and differentiation.Experimental models for identifying modifiers of polyglutamine-induced aggregation and neurodegeneration.Personalized gene silencing therapeutics for Huntington disease.Mammalian nerve globins in search of functions.Challenges of Huntington's disease and quest for therapeutic biomarkers.Cysteine string protein (CSP) and its role in preventing neurodegeneration.
P2860
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P2860
Network organization of the huntingtin proteomic interactome in mammalian brain.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Network organization of the huntingtin proteomic interactome in mammalian brain.
@ast
Network organization of the huntingtin proteomic interactome in mammalian brain.
@en
Network organization of the huntingtin proteomic interactome in mammalian brain.
@nl
type
label
Network organization of the huntingtin proteomic interactome in mammalian brain.
@ast
Network organization of the huntingtin proteomic interactome in mammalian brain.
@en
Network organization of the huntingtin proteomic interactome in mammalian brain.
@nl
prefLabel
Network organization of the huntingtin proteomic interactome in mammalian brain.
@ast
Network organization of the huntingtin proteomic interactome in mammalian brain.
@en
Network organization of the huntingtin proteomic interactome in mammalian brain.
@nl
P2093
P2860
P1433
P1476
Network organization of the huntingtin proteomic interactome in mammalian brain.
@en
P2093
Dyna I Shirasaki
Erin R Greiner
Giovanni Coppola
Ismael Al-Ramahi
Joseph A Loo
Juan Botas
Michelle Gray
Pinmanee Boontheung
Steve Horvath
X William Yang
P2860
P356
10.1016/J.NEURON.2012.05.024
P407
P577
2012-07-01T00:00:00Z