Hypoxia suppresses conversion from proliferative arrest to cellular senescence. - Wikidata - awgldk - TriplyDB

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

http://www.wikidata.org/entity/Q34291377

about

Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases Role of multifaceted regulators in cancer glucose metabolism and their clinical significance Macroautophagy and the oncogene-induced senescence Rapamycin induces pluripotent genes associated with avoidance of replicative senescence Big mice die young but large animals live longer Contact inhibition and high cell density deactivate the mammalian target of rapamycin pathway, thus suppressing the senescence program Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells.Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.From rapalogs to anti-aging formula.Cellular senescence and protein degradation: breaking down cancer Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression.A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling.TOR-centric view on insulin resistance and diabetic complications: perspective for endocrinologists and gerontologists.Selective anti-cancer agents as anti-aging drugs Biphasic regulation of autophagy by miR-96 in prostate cancer cells under hypoxia.Failure of anti tumor-derived endothelial cell immunotherapy depends on augmentation of tumor hypoxia.Senescence of tumor cells induced by oxaliplatin increases the efficiency of a lipid A immunotherapy via the recruitment of neutrophils.Gerosuppression in confluent cells.Senescent cardiac fibroblast is critical for cardiac fibrosis after myocardial infarction.Weekly administration of rapamycin improves survival and biomarkers in obese male mice on high-fat diet Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion.Hypoxia induces an undifferentiated phenotype of oral keratinocytes in vitro Pleiotropic modes of action in tumor cells of RNASET2, an evolutionary highly conserved extracellular RNase.Telomerase deficiency delays renal recovery in mice after ischemia-reperfusion injury by impairing autophagy Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp.Fasting levels of hepatic p-S6 are increased in old mice Geroconversion: irreversible step to cellular senescence Cell cycle, cytoskeleton dynamics and beyond: the many functions of cyclins and CDK inhibitors Comparison of rapamycin schedules in mice on high-fat diet.Rejuvenating immunity: "anti-aging drug today" eight years later.Matters of life and breath: A role for hypoxia in determining cell state.Koschei the immortal and anti-aging drugs Dual mTORC1/C2 inhibitors suppress cellular geroconversion (a senescence program).eIF4E binding protein 1 expression is associated with clinical survival outcomes in colorectal cancer Hypoxia and gerosuppression: the mTOR saga continues SIP1 is a downstream effector of GADD45G in senescence induction and growth inhibition of liver tumor cells.A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype Resveratrol potentiates rapamycin to prevent hyperinsulinemia and obesity in male mice on high fat diet.Answering the ultimate question "what is the proximal cause of aging?"Recent discoveries in the cycling, growing and aging of the p53 field

P2860

Q26750099-A097EBC9-E89B-4BF4-B8B5-04F55F0B5CB6 Q26765039-450282E3-560E-4A44-A465-C22A763CB88E Q26863440-804C4A74-B4B5-4143-A4F1-43E8BDF2B1B3 Q28572137-5D62BF27-DA61-40FE-9805-278702E46133 Q28704146-4540220C-1211-48AB-8F30-A3898DB8ABFB Q28972583-BDCA9D7B-6302-45F8-852F-A2CA2CA3EBCC Q30533934-1D4E08BD-0E8E-4B1A-9450-486973CB7ACA Q33112680-8EA3EA48-C030-4BE6-88E6-9D29BE23E197 Q33829205-AA28EEBC-3778-4691-B244-FF88F849D9D0 Q33953067-3414906F-779D-45AA-80B4-50434D7209BF Q34060715-E7CFBDDA-1B81-4417-BA95-DC5323BF84BC Q34334455-AF283E0F-B2A6-48D2-9418-044B3BF2261E Q34391710-E082A0DB-A9A6-4CD6-AA1D-5BD84BE5FDE3 Q34392470-72BBCC99-F58A-409E-8FB2-C9454789DC17 Q34619280-FE895F1B-4813-4DC0-BA08-70268D335F27 Q34786452-EA33425B-A111-40EF-8F93-08E17F98B16F Q34956634-8B6D3475-D5DC-4F67-9F16-C8A6F803BB3A Q34982499-4FD522FE-6BFF-48A5-880D-CE0AB2548EDE Q34990106-8D645E8A-3EE2-4982-9B91-007BB3601E76 Q35080619-CFBF08D9-1E27-4475-B10E-B1829D5FF987 Q35149607-5418BC8E-C452-4FF7-BFDA-DC0D84A8FF07 Q35541543-4D0C3011-BAC1-474D-9DFB-8D03AD18AE80 Q35781442-8C003B7E-C45F-42E1-84CF-7401353DF739 Q35812423-DE4EEB4F-B8E2-4291-ACA4-CAD8B1839607 Q35852614-40993EFD-4949-4D7A-9E76-6244A663A4AC Q36182265-5D3C1765-C77A-4CC1-9733-F9519A0345C2 Q36186369-D3808E16-3D4B-475F-A49A-1B5B9B9AF7DC Q36188773-27985230-4C93-488F-85B1-9E12F2752F49 Q36189078-F6433B7A-4D15-4521-B621-A67739D2D195 Q36260537-CE4ADDBD-2264-424F-AAF2-2A8AC04D38A6 Q36288639-E8CA5C11-2986-44AB-9353-34593100A3B1 Q36292001-77415900-0755-4DFC-A95F-7C94B61A59BA Q36414149-74779072-F177-45F4-93E5-9CAD99412630 Q36414386-1D8F295F-1C09-4EBC-B89C-B9F0AFE9A8C3 Q36426478-0222258A-4006-4085-B149-F2A45935AA09 Q36545237-45CB4D10-9958-4D8A-82A7-53D8F22D7CBE Q36545528-21AB29AF-97E6-421B-9BE7-55CE6F1CB66F Q36586516-49B48615-73E9-457A-9BAB-DFBED8265D62 Q36736351-1A68C69A-2876-4779-A5B0-FA9C3B792002 Q36736358-1415F7C8-760F-4F73-8CB3-3C4F25451696

P2860

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

http://www.wikidata.org/entity/Q34291377

description

2012 nî lūn-bûn

@nan

2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

@ast

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

@en

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

@nl

type

label

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

@ast

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

@en

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

@nl

prefLabel

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

@ast

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

@en

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

@nl

P1433

Q34291377-A441C79B-7ECB-4104-87BB-BB5F1081596C

P1476

Q34291377-52B58495-990B-4AE4-A8BF-0475A2FAF7C7

P2093

Q34291377-0DAF19E7-0B4F-47CD-9761-E35F0BF79C33

Q34291377-2A5D6D3B-323C-4EB4-9C0A-FEFA3AB82040

Q34291377-6F26DBFC-A710-476C-8C95-8F265A76D544

Q34291377-A20F86AA-4FBB-46F8-91AE-C8233790EECC

Q34291377-B28CE553-7D38-4342-8BB1-4E37F181DA12

P2860

Q34291377-03CD0FC3-5AA1-4149-BDB3-1E259F0D049C

Q34291377-045C0CFC-C2A0-4801-8B3E-41A5AE49E055

Q34291377-05E4C76B-DEC8-4349-8124-8C393B762E82

Q34291377-0FA015C9-AE6C-47B9-B36A-1EABF68826D1

Q34291377-10AACF73-787F-4407-A75D-8FEA974E385E

Q34291377-1B3B61F4-ECAC-482E-9456-FB7E7AC438B7

Q34291377-1DCE82DB-2246-4B79-88EC-A744062B1A61

Q34291377-23703AB7-4D4E-4009-AC6B-768DE53E2640

Q34291377-23C72A4E-DDD2-468C-A176-1BDF711BB294

Q34291377-29A5AC3E-D905-44EE-B402-E28CA78F07E5

P304

Q34291377-8A6DD2BE-82C0-4F67-A2A9-7A024051EB9E

P31

Q34291377-20ED4841-138B-4AD7-AAAC-D005D3DB0EB3

P356

Q34291377-E08444EC-8BBE-4B28-863A-34C0A875F50C

P407

Q34291377-E4F24A7C-76B0-4230-9011-B1E7A2434CE0

P433

Q34291377-6178DB85-5575-49B1-8A36-4467894A6F99

P478

Q34291377-76C0C4C9-F4E1-4DC4-873D-474C6957E594

P50

Q34291377-80DBB41A-9558-4E6E-B044-7CFBFCDBB071

P577

Q34291377-9356A1B6-F8A3-4C3A-AEB7-EB5F1462D912

P5875

Q34291377-98D2F4AE-5B45-424B-B30D-C38450147230

P698

Q34291377-6B913C22-FE00-46B1-B68E-9A4040A7CA94

P921

Q34291377-700B54C8-3D57-467B-8909-41279154C51F

P932

Q34291377-6AA56255-885F-452F-B5AA-00442B155AD6

P356

PNAS.1205690109

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Hypoxia suppresses conversion from proliferative arrest to cellular senescence.

@en

P2093

Andrei V Gudkov

http://www.w3.org/2001/XMLSchema#string

Lyudmila G Burdelya

http://www.w3.org/2001/XMLSchema#string

Olga V Leontieva

http://www.w3.org/2001/XMLSchema#string

Venkatesh Natarajan

http://www.w3.org/2001/XMLSchema#string

Zoya N Demidenko

http://www.w3.org/2001/XMLSchema#string

P2860

Regulation of mTOR and cell growth in response to energy stress by REDD1.

Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling

TOR signaling in growth and metabolism

Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

P304

13314-13318

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1205690109

http://www.w3.org/2001/XMLSchema#string

P407

P433

33

http://www.w3.org/2001/XMLSchema#string

P478

109

http://www.w3.org/2001/XMLSchema#string

P50

Mikhail Blagosklonny

P577

2012-07-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

230589101

http://www.w3.org/2001/XMLSchema#string

P698

22847439

http://www.w3.org/2001/XMLSchema#string

P921

P932

3421205

http://www.w3.org/2001/XMLSchema#string