The "bystander effect": association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice.
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Current and Future Gene Therapy for Malignant GliomasEnhancement of tumor ablation by a selected HSV-1 thymidine kinase mutant.Ganciclovir-mediated in vivo elimination of myeloid leukemic cells expressing the HSVtk gene induces HSVtk loss variants.Characterization of herpes simplex virus type 1 thymidine kinase mutants engineered for improved ganciclovir or acyclovir activity.Tissue-specific expression of herpes simplex virus thymidine kinase gene delivered by adeno-associated virus inhibits the growth of human hepatocellular carcinoma in athymic mice.Combination gene delivery of the cell cycle inhibitor p27 with thymidine kinase enhances prodrug cytotoxicityGenetically engineered HSV in the treatment of glioma: a review.In situ use of suicide genes for therapy of brain tumours.Gene directed enzyme/prodrug therapy of cancer: historical appraisal and future prospectives.In situ gene therapy for prostate cancer: immunomodulatory approaches.The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor.The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumorsOxidative stress, lens gap junctions, and cataractsConnexin43 increases the sensitivity of prostate cancer cells to TNFalpha-induced apoptosis.Connexins as therapeutic targets in lung disease.Emerging implications of nonmammalian cytosine deaminases on cancer therapeutics.Involvement of Fas (CD95/APO-1) and Fas ligand in apoptosis induced by ganciclovir treatment of tumor cells transduced with herpes simplex virus thymidine kinase.Conditional Cytotoxic Anti-HIV Gene Therapy for Selectable Cell Modification.An armed, YB-1-dependent oncolytic adenovirus as a candidate for a combinatorial anti-glioma approach of virotherapy, suicide gene therapy and chemotherapeutic treatment.Bystander-mediated regression of murine neuroblastoma via retroviral transfer of the HSV-TK gene.Tumor-specific gene expression using regulatory elements of the glucose transporter isoform 1 gene.Purified herpes simplex virus thymidine kinase retroviral particles: III. Characterization of bystander killing mechanisms in transfected tumor cells.Gene therapy for neurologic disease: benchtop discoveries to bedside applications. 1. The bench.Effects of retroviral-mediated herpes simplex virus thymidine kinase gene transfer to murine neuroblastoma cell lines in vitro and in vivo.Combination suicide/cytokine gene therapy as adjuvants to a defective herpes simplex virus-based cancer vaccine.Appropriate subcellular localisation of prodrug-activating enzymes has important consequences for suicide gene therapy.Cancer gene therapy with HSV-tk/GCV system depends on T-cell-mediated immune responses and causes apoptotic death of tumor cells in vivo.The role of herpes simplex virus thymidine kinase in the treatment of solid tumours.Expression of thymidine kinase driven by an endothelial-specific promoter inhibits tumor growth of Lewis lung carcinoma cells in transgenic mice.Retrovirus-mediated in vivo gene therapy using the herpes simplex virus thymidine kinase gene against carcinomatous peritonitis.Comparison of gene therapy with the herpes simplex virus thymidine kinase gene and the bacterial cytosine deaminase gene for the treatment of hepatocellular carcinoma.Enhanced pancreatic tumor regression by a combination of adenovirus and retrovirus-mediated delivery of the herpes simplex virus thymidine kinase gene.Adenovirus-mediated suicide gene therapy in an in vitro model of reactive gliosis.In vivo 31P MRS evaluation of ganciclovir toxicity in C6 gliomas stably expressing the herpes simplex thymidine kinase gene.Influence of vascular endothelial growth factor and radiation on gap junctional intercellular communication in glioblastoma multiforme cell lines.
P2860
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P2860
The "bystander effect": association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice.
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The "bystander effect": associ ...... ack of effect in athymic mice.
@ast
The "bystander effect": associ ...... ack of effect in athymic mice.
@en
The "bystander effect": associ ...... ack of effect in athymic mice.
@nl
type
label
The "bystander effect": associ ...... ack of effect in athymic mice.
@ast
The "bystander effect": associ ...... ack of effect in athymic mice.
@en
The "bystander effect": associ ...... ack of effect in athymic mice.
@nl
prefLabel
The "bystander effect": associ ...... ack of effect in athymic mice.
@ast
The "bystander effect": associ ...... ack of effect in athymic mice.
@en
The "bystander effect": associ ...... ack of effect in athymic mice.
@nl
P2093
P356
P1433
P1476
The "bystander effect": associ ...... lack of effect in athymic mice
@en
P2093
P304
P356
10.1089/HUM.1995.6.6-763
P577
1995-06-01T00:00:00Z