Differential effect of troglitazone on the human bile acid transporters, MRP2 and BSEP, in the PXB hepatic chimeric mouse.

Differential effect of troglitazone on the human bile acid transporters, MRP2 and BSEP, in the PXB hepatic chimeric mouse.

Item
http://www.wikidata.org/entity/Q34294773
Assessment of chimeric mice with humanized livers in new drug development: generation of pharmacokinetics, metabolism and toxicity data for selecting the final candidate compound.A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism.Chimeric rodents with humanized liver: bridging the preclinical/clinical trial gap in ADME/toxicity studies.The application of engineered liver tissues for novel drug discovery.Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity.Chimeric mice with hepatocyte-humanized liver as an appropriate model to study human peroxisome proliferator-activated receptor-α.Endogenous and xenobiotic metabolite profiling of liver extracts from SCID and chimeric humanized mice following repeated oral administration of troglitazone.
P2860

Differential effect of troglitazone on the human bile acid transporters, MRP2 and BSEP, in the PXB hepatic chimeric mouse.

Item
http://www.wikidata.org/entity/Q34294773
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Differential effect of troglit ...... he PXB hepatic chimeric mouse.
@ast
Differential effect of troglit ...... he PXB hepatic chimeric mouse.
@en
Differential effect of troglit ...... he PXB hepatic chimeric mouse.
@nl
type
label
Differential effect of troglit ...... he PXB hepatic chimeric mouse.
@ast
Differential effect of troglit ...... he PXB hepatic chimeric mouse.
@en
Differential effect of troglit ...... he PXB hepatic chimeric mouse.
@nl
prefLabel
Differential effect of troglit ...... he PXB hepatic chimeric mouse.
@ast
Differential effect of troglit ...... he PXB hepatic chimeric mouse.
@en
Differential effect of troglit ...... he PXB hepatic chimeric mouse.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Differential effect of troglit ...... the PXB hepatic chimeric mouse
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698