Dephosphorylation of Cdk2 Thr160 by the cyclin-dependent kinase-interacting phosphatase KAP in the absence of cyclin.
about
Identification of novel mitosis regulators through data mining with human centromere/kinetochore proteins as group queriesOverexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expressionBinding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2Human HTm4 is a hematopoietic cell cycle regulatorRegulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatasesCholine availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 geneSpecialized roles of the two mitotic cyclins in somatic cells: cyclin A as an activator of M phase-promoting factorEffects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activityExtracellular regulated kinases (ERK) 1 and ERK2 are authentic substrates for the dual-specificity protein-tyrosine phosphatase VHR. A novel role in down-regulating the ERK pathwayDephosphorylation of human cyclin-dependent kinases by protein phosphatase type 2C alpha and beta 2 isoformsCharacterization of the cullin and F-box protein partner Skp1Identification of functional domains in the neuronal Cdk5 activator proteinMachine learning methods for prediction of CDK-inhibitorsProtein phosphatase 2A promotes the transition to G0 during terminal differentiation in DrosophilaInhibitory phosphorylation of cyclin-dependent kinase 1 as a compensatory mechanism for mitosis exit.Thr-161 phosphorylation of monomeric Cdc2. Regulation by protein phosphatase 2C in Xenopus oocytes.3-phosphoinositide-dependent protein kinase 1, an Akt1 kinase, is involved in dephosphorylation of Thr-308 of Akt1 in Chinese hamster ovary cells.Regulation of the G1 phase of the mammalian cell cycle.Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a)Dna damage-induced G(1) arrest in hematopoietic cells is overridden following phosphatidylinositol 3-kinase-dependent activation of cyclin-dependent kinase 2Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae.Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.Strategies in subversion: de-regulation of the mammalian cell cycle by viral gene products.Novel functions of the phosphatase SHP2 in the DNA replication and damage checkpoints.The tumor suppressor CDKN3 controls mitosis.Targeting protein tyrosine phosphatases for anticancer drug discovery.Coupling of T161 and T14 phosphorylations protects cyclin B-CDK1 from premature activation.Cdc14 phosphatases preferentially dephosphorylate a subset of cyclin-dependent kinase (Cdk) sites containing phosphoserineRequirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.Catalytic mechanism and kinase interactions of ABA-signaling PP2C phosphatases.Activation and inhibition of cyclin-dependent kinase-2 by phosphorylation; a molecular dynamics study reveals the functional importance of the glycine-rich loop.Dephosphorylation of threonine 169 of Cdc28 is not required for exit from mitosis but may be necessary for start in Saccharomyces cerevisiae.Cyclin-dependent kinase-associated protein phosphatase is overexpressed in alcohol-related hepatocellular carcinoma and influences xenograft tumor growth.Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activityThe CDK Network: Linking Cycles of Cell Division and Gene Expression.A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progressionDistinct activation pathways confer cyclin-binding specificity on Cdk1 and Cdk2 in human cellsMolecular mechanisms of the PRL phosphatases.Expression and alternative splicing of the cyclin-dependent kinase inhibitor-3 gene in human cancer.
P2860
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P2860
Dephosphorylation of Cdk2 Thr160 by the cyclin-dependent kinase-interacting phosphatase KAP in the absence of cyclin.
description
1995 nî lūn-bûn
@nan
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Dephosphorylation of Cdk2 Thr1 ...... KAP in the absence of cyclin.
@ast
Dephosphorylation of Cdk2 Thr1 ...... KAP in the absence of cyclin.
@en
Dephosphorylation of Cdk2 Thr1 ...... KAP in the absence of cyclin.
@nl
type
label
Dephosphorylation of Cdk2 Thr1 ...... KAP in the absence of cyclin.
@ast
Dephosphorylation of Cdk2 Thr1 ...... KAP in the absence of cyclin.
@en
Dephosphorylation of Cdk2 Thr1 ...... KAP in the absence of cyclin.
@nl
prefLabel
Dephosphorylation of Cdk2 Thr1 ...... KAP in the absence of cyclin.
@ast
Dephosphorylation of Cdk2 Thr1 ...... KAP in the absence of cyclin.
@en
Dephosphorylation of Cdk2 Thr1 ...... KAP in the absence of cyclin.
@nl
P1433
P1476
Dephosphorylation of Cdk2 Thr1 ...... KAP in the absence of cyclin.
@en
P2093
P356
10.1126/SCIENCE.270.5233.90
P407
P577
1995-10-01T00:00:00Z