Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer.
about
High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencingComprehensive assessment of sequence variation within the copy number variable defensin cluster on 8p23 by target enriched in-depth 454 sequencing.Targeted isolation of cloned genomic regions by recombineering for haplotype phasing and isogenic targeting.Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions.Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease.RET fusion as a novel driver of medullary thyroid carcinomaGenetic and biochemical alterations in non-small cell lung cancer.Cancer genes in lung cancer: racial disparities: are there any?Restored expression of vitamin D receptor and sensitivity to 1,25-dihydroxyvitamin D3 in response to disrupted fusion FOP2-FGFR1 gene in acute myeloid leukemia cells.Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies.Application of next generation sequencing to human gene fusion detection: computational tools, features and perspectivesTyrosine kinase gene rearrangements in epithelial malignancies.Genomic biomarkers for patient selection and stratification: the cancer paradigm.ROS1 fusions in cancer: a review.Current companion diagnostics in advanced colorectal cancer; getting a bigger and better piece of the pieSystematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm.CCDC6: the identity of a protein known to be partner in fusion.Anchored multiplex PCR for targeted next-generation sequencing.The rationale for druggability of CCDC6-tyrosine kinase fusions in lung cancer.Fusions in solid tumours: diagnostic strategies, targeted therapy, and acquired resistance.Kinase impact assessment in the landscape of fusion genes that retain kinase domains: a pan-cancer study.Chipping away at the lung cancer genome.Gene Fusion in Malignant Glioma: An Emerging Target for Next-Generation Personalized Treatment.
P2860
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P2860
Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Targeted next-generation seque ...... sine kinase fusions in cancer.
@ast
Targeted next-generation seque ...... sine kinase fusions in cancer.
@en
Targeted next-generation seque ...... sine kinase fusions in cancer.
@nl
type
label
Targeted next-generation seque ...... sine kinase fusions in cancer.
@ast
Targeted next-generation seque ...... sine kinase fusions in cancer.
@en
Targeted next-generation seque ...... sine kinase fusions in cancer.
@nl
prefLabel
Targeted next-generation seque ...... sine kinase fusions in cancer.
@ast
Targeted next-generation seque ...... sine kinase fusions in cancer.
@en
Targeted next-generation seque ...... sine kinase fusions in cancer.
@nl
P2093
P2860
P356
P1476
Targeted next-generation seque ...... sine kinase fusions in cancer.
@en
P2093
Agnes Viale
Katherine Hutchinson
Martin Peifer
Nicholas D Socci
Peilin Jia
Roman K Thomas
Zhongming Zhao
P2860
P304
P356
10.1093/NAR/GKQ579
P407
P577
2010-06-29T00:00:00Z