Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons. - Wikidata - awgldk - TriplyDB

Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons.

Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons.

http://www.wikidata.org/entity/Q34313075

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PEGylated Adenoviruses: From Mice to Monkeys Circumventing antivector immunity: potential use of nonhuman adenoviral vectors A recombinant adenovirus type 35 fiber knob protein sensitizes lymphoma cells to rituximab therapy Evaluation of biodistribution and safety of adenovirus vector containing MDR1 in mice Adenovirus encoding human platelet-derived growth factor-B delivered to alveolar bone defects exhibits safety and biodistribution profiles favorable for clinical use.A phase I double blind, placebo-controlled, randomized study of a multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults.miR-148a- and miR-216a-regulated oncolytic adenoviruses targeting pancreatic tumors attenuate tissue damage without perturbation of miRNA activity Evaluation of adenovirus vectors containing serotype 35 fibers for vaccination Truncated active human matrix metalloproteinase-8 delivered by a chimeric adenovirus-hepatitis B virus vector ameliorates rat liver cirrhosis.Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications.Fiber and penton base capsid modifications yield diminished adenovirus type 5 transduction and proinflammatory gene expression with retention of antigen-specific humoral immunity.Preclinical studies for pharmacokinetics and biodistribution of Ad-stTRAIL, an adenovirus delivering secretable trimeric TRAIL for gene therapy A new human DSG2-transgenic mouse model for studying the tropism and pathology of human adenoviruses.Coagulation factor X mediates adenovirus type 5 liver gene transfer in non-human primates (Microcebus murinus)INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies.Fiber shaft-chimeric adenovirus vectors lacking the KKTK motif efficiently infect liver cells in vivo Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo.Intracardiac injection of a capsid-modified Ad5/35 results in decreased heart toxicity when compared to standard Ad5 Myeloid and plasmacytoid dendritic cells are susceptible to recombinant adenovirus vectors and stimulate polyfunctional memory T cell responses T-cell immunity generated by recombinant adenovirus vaccines.Novel vectors for in vivo gene delivery to vascular tissue.Gene therapy of gynaecological diseases.Targeting of adenovirus serotype 5 pseudotyped with short fiber from serotype 41 to c-erbB2-positive cells using bispecific single-chain diabody.Comparative analysis of vector biodistribution, persistence and gene expression following intravenous delivery of bovine, porcine and human adenoviral vectors in a mouse model.TRAIL recombinant adenovirus triggers robust apoptosis in multidrug-resistant HL-60/Vinc cells preferentially through death receptor DR5 In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors Selective transduction of mature DC in human skin and lymph nodes by CD80/CD86-targeted fiber-modified adenovirus-5/3.CD46-mediated transduction of a species D adenovirus vaccine improves mucosal vaccine efficacy.Tropism-modification strategies for targeted gene delivery using adenoviral vectors.EMMPRIN reduction via scFv-M6-1B9 intrabody affects α3β1-integrin and MCT1 functions and results in suppression of progressive phenotype in the colorectal cancer cell line Caco-2.Preclinical Evaluation of a Replication-Deficient Recombinant Adenovirus Serotype 5 Vaccine Expressing Guanylate Cyclase C and the PADRE T-helper Epitope.Transduction of liver metastases after intravenous injection of Ad5/35 or Ad35 vectors with and without factor X-binding protein pretreatment Fiber-chimeric adenoviruses expressing fibers from serotype 16 and 50 improve gene transfer to human pancreatic adenocarcinoma.Replication-attenuated Human Adenoviral Type 4 vectors elicit capsid dependent enhanced innate immune responses that are partially dependent upon interactions with the complement system.In Vivo Hematopoietic Stem Cell Transduction.Rescue of chimeric adenoviral vectors to expand the serotype repertoire.A new group B adenovirus receptor is expressed at high levels on human stem and tumor cells.Evaluation of adenovirus vectors containing serotype 35 fibers for tumor targeting.Effect of adenovirus-mediated heat shock protein expression and oncolysis in combination with low-dose cyclophosphamide treatment on antitumor immune responses.Biodistribution studies: understanding international expectations.

P2860

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P2860

Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons.

http://www.wikidata.org/entity/Q34313075

description

2005 nî lūn-bûn

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2005 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2005 թվականի հունիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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Evaluation of biodistribution ...... venous injection into baboons.

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Evaluation of biodistribution ...... venous injection into baboons.

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Evaluation of biodistribution ...... venous injection into baboons.

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Evaluation of biodistribution ...... venous injection into baboons.

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Evaluation of biodistribution ...... venous injection into baboons.

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Evaluation of biodistribution ...... venous injection into baboons.

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Evaluation of biodistribution ...... venous injection into baboons.

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Evaluation of biodistribution ...... venous injection into baboons.

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Evaluation of biodistribution ...... venous injection into baboons.

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Human Gene Therapy

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Evaluation of biodistribution ...... avenous injection into baboons

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André Lieber

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Anuj Gaggar

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Hans-Peter Kiem

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Shaoheng Ni

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Zong-Yi Li

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P2860

Four viruses, two bacteria, and one receptor: membrane cofactor protein (CD46) as pathogens' magnet

Exploiting the natural diversity in adenovirus tropism for therapy and prevention of disease.

Mechanism of measles virus-induced suppression of inflammatory immune responses.

Efficient infection of primitive hematopoietic stem cells by modified adenovirus.

The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3

Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.

Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons.

A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency.

Reactivation of the previously silenced cytomegalovirus major immediate-early promoter in the mouse liver: involvement of NFkappaB.

Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vector

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6

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16

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Kathrin M. Bernt

Kathrin M Bernt

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7781918

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1351080

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