Mechanisms of double-strand break repair in somatic mammalian cells. - Wikidata - awgldk - TriplyDB

Mechanisms of double-strand break repair in somatic mammalian cells.

Mechanisms of double-strand break repair in somatic mammalian cells.

http://www.wikidata.org/entity/Q34317108

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DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells Synaptonemal complex protein SYCP3 impairs mitotic recombination by interfering with BRCA2 Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications Radio-resistant mesenchymal stem cells: mechanisms of resistance and potential implications for the clinic Modulation of DNA damage and repair pathways by human tumour viruses Transcription activator-like effectors: a toolkit for synthetic biology Targeting DNA damage response in cancer therapy Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family Therapeutic targeting of a robust non-oncogene addiction to PRKDC in ATM-defective tumors.The DNA Damage Response: Making It Safe to Play with Knives Differential requirement for SUB1 in chromosomal and plasmid double-strand DNA break repair Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction A dual role for A-type lamins in DNA double-strand break repair Heat shock protein 90α (Hsp90α) is phosphorylated in response to DNA damage and accumulates in repair foci c-MYC Generates Repair Errors via Increased Transcription of Alternative-NHEJ Factors, LIG3 and PARP1, in Tyrosine Kinase-Activated Leukemias Role of MRE11 in cell proliferation, tumor invasion, and DNA repair in breast cancer Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond Mutants of Cre recombinase with improved accuracy Shorter exposures to harder X-rays trigger early apoptotic events in Xenopus laevis embryos An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair Double strand break repair functions of histone H2AX In vivo importance of homologous recombination DNA repair for mouse neural stem and progenitor cells A noncatalytic function of the ligation complex during nonhomologous end joining.Involvement of AtPolλ in the repair of high salt- and DNA cross-linking agent-induced double strand breaks in Arabidopsis.Developmental and pathological changes in the human cardiac muscle mitochondrial DNA organization, replication and copy number Zinc finger nucleases as tools to understand and treat human diseases.A high-throughput chemical screen with FDA approved drugs reveals that the antihypertensive drug Spironolactone impairs cancer cell survival by inhibiting homology directed repair A role of human RNase P subunits, Rpp29 and Rpp21, in homology directed-repair of double-strand breaks.Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle.Update on gene therapy for immunodeficiencies.Relevance of DNA repair gene polymorphisms to gastric cancer risk and phenotype DNA damage and lamins Cell cycle-dependent induction of homologous recombination by a tightly regulated I-SceI fusion protein.PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage Sequence conversion by single strand oligonucleotide donors via non-homologous end joining in mammalian cells

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Mechanisms of double-strand break repair in somatic mammalian cells.

http://www.wikidata.org/entity/Q34317108

description

2009 nî lūn-bûn

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2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Mechanisms of double-strand break repair in somatic mammalian cells.

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Mechanisms of double-strand break repair in somatic mammalian cells.

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Mechanisms of double-strand break repair in somatic mammalian cells.

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type

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Mechanisms of double-strand break repair in somatic mammalian cells.

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Mechanisms of double-strand break repair in somatic mammalian cells.

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Mechanisms of double-strand break repair in somatic mammalian cells.

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Mechanisms of double-strand break repair in somatic mammalian cells.

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Mechanisms of double-strand break repair in somatic mammalian cells.

@en

Mechanisms of double-strand break repair in somatic mammalian cells.

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Biochemical Journal

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Mechanisms of double-strand break repair in somatic mammalian cells.

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Andrea J Hartlerode

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Ralph Scully

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P2860

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

MDC1 is a mediator of the mammalian DNA damage checkpoint

Phosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinase

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

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157-168

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10.1042/BJ20090942

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2

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423

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2009-09-25T00:00:00Z

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19772495

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2983087

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