SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation.
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An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cellsCTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanismsThe PD-1 pathway in tolerance and autoimmunityGenetic engineering of T cells for adoptive immunotherapyInteractions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.T cell activationClinical utility of nivolumab in the treatment of advanced melanomaCancer immunotherapy: the beginning of the end of cancer?Biochemical and Functional Insights into the Integrated Regulation of Innate Immune Cell Responses by Teleost Leukocyte Immune-Type ReceptorsProgrammed cell death protein-1/programmed cell death ligand-1 pathway inhibition and predictive biomarkers: understanding transforming growth factor-beta roleOverview of current immunotherapeutic strategies for gliomaTargeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor ImmunityHuman Cancer Immunotherapy with PD-1/PD-L1 BlockadeAntibody-based immunotherapy of solid cancers: progress and possibilitiesMolecular and cellular insights into T cell exhaustionUnderstanding the function and dysfunction of the immune system in lung cancer: the role of immune checkpointsRole of the PD-1 pathway in the immune responseOvercoming T cell exhaustion in infection and cancerNew immunotherapies targeting the PD-1 pathwayHerpesvirus exploitation of host immune inhibitory pathwaysTolerance and Cross-Tolerance following Toll-Like Receptor (TLR)-4 and -9 Activation Are Mediated by IRAK-M and Modulated by IL-7 in Murine SplenocytesEarly T cell signalling is reversibly altered in PD-1+ T lymphocytes infiltrating human tumorsLiver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 ExpressionCostimulatory molecule programmed death-1 in the cytotoxic response during chronic hepatitis CThe PD1:PD-L1/2 Pathway from Discovery to Clinical ImplementationAptamers: A New Technological Platform in Cancer ImmunotherapyGenetic barriers in transplantation medicineDiacylglycerol Kinases (DGKs): Novel Targets for Improving T Cell Activity in CancerTumor Microenvironment Metabolism: A New Checkpoint for Anti-Tumor ImmunityHarnessing the Power of Onco-Immunotherapy with Checkpoint InhibitorsThe DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell responsesTIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling PathwayPD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8+ T cellsContribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasionThe role of the PD-1 pathway in autoimmunity and peripheral toleranceAn investigation of hierachical protein recruitment to the inhibitory platelet receptor, G6B-bVstm3 is a member of the CD28 family and an important modulator of T-cell functionExtrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cellsLymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.Strategies and challenges in eliciting immunity to melanoma.
P2860
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P2860
SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
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2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
name
SHP-1 and SHP-2 associate with ...... on prevents T cell activation.
@ast
SHP-1 and SHP-2 associate with ...... on prevents T cell activation.
@en
SHP-1 and SHP-2 associate with ...... on prevents T cell activation.
@nl
type
label
SHP-1 and SHP-2 associate with ...... on prevents T cell activation.
@ast
SHP-1 and SHP-2 associate with ...... on prevents T cell activation.
@en
SHP-1 and SHP-2 associate with ...... on prevents T cell activation.
@nl
prefLabel
SHP-1 and SHP-2 associate with ...... on prevents T cell activation.
@ast
SHP-1 and SHP-2 associate with ...... on prevents T cell activation.
@en
SHP-1 and SHP-2 associate with ...... on prevents T cell activation.
@nl
P2093
P1476
SHP-1 and SHP-2 associate with ...... on prevents T cell activation.
@en
P2093
Carl H June
James L Riley
Jens M Chemnitz
Kim E Nichols
Richard V Parry
P304
P356
10.4049/JIMMUNOL.173.2.945
P407
P577
2004-07-01T00:00:00Z