Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
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A new role of NUAK1: directly phosphorylating p53 and regulating cell proliferationSubstrate-Induced Conformational Changes Occur in All Cleaved Forms of Caspase-6Zinc-mediated Allosteric Inhibition of Caspase-6Inhibitory Mechanism of Caspase-6 Phosphorylation Revealed by Crystal Structures, Molecular Dynamics Simulations, and Biochemical AssaysPhosphorylation regulates assembly of the caspase-6 substrate-binding groove.Cross-talk between JIP3 and JIP1 during glucose deprivation: SEK1-JNK2 and Akt1 act as mediatorsNDR2 acts as the upstream kinase of ARK5 during insulin-like growth factor-1 signaling.A multipronged approach for compiling a global map of allosteric regulation in the apoptotic caspases.5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments.Membrane rafts segregate pro- from anti-apoptotic insulin-like growth factor-I receptor signaling in colon carcinoma cells stimulated by members of the tumor necrosis factor superfamily.Dissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1-MEK-JNK signal transduction pathway during metabolic oxidative stress: a negative feedback loop.Review article: immune suppression and colorectal cancer.The LKB1 complex-AMPK pathway: the tree that hides the forestCellular mechanisms controlling caspase activation and function.Caspase-6 as a novel early target in the treatment of Alzheimer's disease.Overexpression of NUAK1 is associated with disease-free survival and overall survival in patients with gastric cancer.Tumor-Associated Mutations in Caspase-6 Negatively Impact Catalytic Efficiency.Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model.Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD.Caspase-6 Undergoes a Distinct Helix-Strand Interconversion upon Substrate Binding.High NUAK1 expression correlates with poor prognosis and involved in NSCLC cells migration and invasion.ARK5 is associated with the invasive and metastatic potential of human breast cancer cells.AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells.The commensal Streptococcus salivarius K12 downregulates the innate immune responses of human epithelial cells and promotes host-microbe homeostasis.Involvement of transforming growth factor-beta 1 signaling in hypoxia-induced tolerance to glucose starvation.Metformin protects rat hepatocytes against bile acid-induced apoptosisPalmitoylation of caspase-6 by HIP14 regulates its activation.Dual Site Phosphorylation of Caspase-7 by PAK2 Blocks Apoptotic Activity by Two Distinct Mechanisms.Ηypoxia-inducible factor 1-α promotes colon cell proliferation and migration by upregulating AMPK-related protein kinase 5 under hypoxic conditions.Multiple proteolytic events in caspase-6 self-activation impact conformations of discrete structural regions.Neural tube defects by NUAK1 and NUAK2 double mutation.
P2860
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P2860
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
@ast
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
@en
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
@nl
type
label
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
@ast
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
@en
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
@nl
prefLabel
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
@ast
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
@en
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
@nl
P2093
P2860
P356
P1433
P1476
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
@en
P2093
Atsuhiro Kishimoto
Atsushi Ochiai
Atsushi Suzuki
Gen-Ichi Kusakai
Hiroyasu Esumi
Sińichi Miyamoto
Tsutomu Ogura
Yosuke Shimojo
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207963
P407
P577
2004-09-01T00:00:00Z
P6179
1004583155