Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells - Wikidata - awgldk - TriplyDB

Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells

Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells

http://www.wikidata.org/entity/Q34350253

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Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy Engineering approaches for regeneration of T lymphopoiesis Alternative Donor Transplantation for Acute Myeloid Leukemia Advances in umbilical cord blood manipulation-from niche to bedside The evolving role of the aryl hydrocarbon receptor (AHR) in the normophysiology of hematopoiesis Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling Acellular bone marrow extracts significantly enhance engraftment levels of human hematopoietic stem cells in mouse xeno-transplantation models Disruption of Notch signaling aggravates irradiation-induced bone marrow injury, which is ameliorated by a soluble Dll1 ligand through Csf2rb2 upregulation Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade Single-unit dominance after double-unit umbilical cord blood transplantation coincides with a specific CD8+ T-cell response against the nonengrafted unit.Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution.Notch-Expanded Murine Hematopoietic Stem and Progenitor Cells Mitigate Death from Lethal Radiation and Convey Immune Tolerance in Mismatched Recipients.A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells T cells fail to develop in the human skin-cell explants system; an inconvenient truth Strategies to enhance umbilical cord blood stem cell engraftment in adult patients.Haploidentical vs cord blood transplantation for adults with acute myelogenous leukemia.Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.Erythrocyte enrichment in hematopoietic progenitor cell cultures based on magnetic susceptibility of the hemoglobin.Transcriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E(spl)/Hes genes.Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells The role of the thymus in T-cell immune reconstitution after umbilical cord blood transplantation Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation.NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth NOTCH-Mediated Maintenance and Expansion of Human Bone Marrow Stromal/Stem Cells: A Technology Designed for Orthopedic Regenerative Medicine.Notch signaling in the malignant bone marrow microenvironment: implications for a niche-based model of oncogenesis.Cord blood-derived hematopoietic stem/progenitor cells: current challenges in engraftment, infection, and ex vivo expansion.Generation of hematopoietic humanized mice in the newborn BALB/c-Rag2null Il2rγnull mouse model: a multivariable optimization approach Ex vivo expansion of human hematopoietic stem and progenitor cells.The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs SALL4 is a robust stimulator for the expansion of hematopoietic stem cells.Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis Resuscitating cancer immunosurveillance: selective stimulation of DLL1-Notch signaling in T cells rescues T-cell function and inhibits tumor growth.The NOTCH signaling pathway in normal and malignant blood cell production.Osteoblastic and vascular endothelial niches, their control on normal hematopoietic stem cells, and their consequences on the development of leukemia Hematopoietic stem cells: transcriptional regulation, ex vivo expansion and clinical application.Development of feeder-free culture systems for generation of ckit+sca1+ progenitors from mouse iPS cells.Increased Engraftment of Human Short Term Repopulating Hematopoietic Cells in NOD/SCID/IL2rγnull Mice by Lentiviral Expression of NUP98-HOXA10HD HOXB4's road map to stem cell expansion.The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironment Jagged-1 Signaling in the Bone Marrow Microenvironment Promotes Endothelial Progenitor Cell Expansion and Commitment of CD133+ Human Cord Blood Cells for Postnatal Vasculogenesis.

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Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells

http://www.wikidata.org/entity/Q34350253

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2005 nî lūn-bûn

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2005 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2005年の論文

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Barbara Varnum-Finney

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Carolyn Brashem-Stein

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Colleen Delaney

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Irwin D Bernstein

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Keisuke Aoyama

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P2860

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells

Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation

Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations

Delta-1 enhances marrow and thymus repopulating ability of human CD34(+)CD38(-) cord blood cells

A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells

HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo

Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function.

Notch1 and T-cell development: insights from conditional knockout mice.

Deciphering the role of Notch signaling in lymphopoiesis.

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