Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm.
about
Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decayEvidence for haploinsufficiency of the human HNF1alpha gene revealed by functional characterization of MODY3-associated mutationsCharacterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1.Non-structural protein 1 of influenza viruses inhibits rapid mRNA degradation mediated by double-stranded RNA-binding protein, staufen1eIF4G is required for the pioneer round of translation in mammalian cellsNMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNAA new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translationA competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decayMagoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex.The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling.A 3' UTR sequence stabilizes termination codons in the unspliced RNA of Rous sarcoma virus.Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeastThe spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctionsPre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctionsA nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decayNonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathwaysThe canonical UPF1-dependent nonsense-mediated mRNA decay is inhibited in transcripts carrying a short open reading frame independent of sequence contextSuppression of nonsense-mediated mRNA decay permits unbiased gene trapping in mouse embryonic stem cellsNonsense-mediated mRNA decay among coagulation factor genesMechanism and regulation of the nonsense-mediated decay pathwayNuclear import of Upf3p is mediated by importin-alpha/-beta and export to the cytoplasm is required for a functional nonsense-mediated mRNA decay pathway in yeastTargeting of aberrant mRNAs to cytoplasmic processing bodies.Nonsense-mediated mRNA decay in humans at a glanceNonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryDirect and indirect contributions of RNA secondary structure elements to the initiation of HIV-1 reverse transcriptionIntrons in UTRs: why we should stop ignoring themOrganizing principles of mammalian nonsense-mediated mRNA decayNonsense-mediated decay of mRNA for the selenoprotein phospholipid hydroperoxide glutathione peroxidase is detectable in cultured cells but masked or inhibited in rat tissuesRP1 is required for the correct stacking of outer segment discsRapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathwayThe exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decayTrafficking through the Rev/RRE pathway is essential for efficient inhibition of human immunodeficiency virus type 1 by an antisense RNA derived from the envelope gene.Out-of-frame T cell receptor beta transcripts are eliminated by multiple pathways in vivoSpecies- and tissue-specific physiological regulation of vasopressin mRNA poly(A) tail length.A nonsense mutation in S-antigen (p.Glu306*) causes Oguchi disease.A sequence similar to tRNA 3 Lys gene is embedded in HIV-1 U3-R and promotes minus-strand transfer.Splicing of U12-type introns deposits an exon junction complex competent to induce nonsense-mediated mRNA decay.Regulation of AUF1 expression via conserved alternatively spliced elements in the 3' untranslated regionmRNA surveillance in eukaryotes: kinetic proofreading of proper translation termination as assessed by mRNP domain organization?
P2860
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P2860
Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Intron function in the nonsens ...... translation in the cytoplasm.
@ast
Intron function in the nonsens ...... translation in the cytoplasm.
@en
Intron function in the nonsens ...... translation in the cytoplasm.
@nl
type
label
Intron function in the nonsens ...... translation in the cytoplasm.
@ast
Intron function in the nonsens ...... translation in the cytoplasm.
@en
Intron function in the nonsens ...... translation in the cytoplasm.
@nl
prefLabel
Intron function in the nonsens ...... translation in the cytoplasm.
@ast
Intron function in the nonsens ...... translation in the cytoplasm.
@en
Intron function in the nonsens ...... translation in the cytoplasm.
@nl
P2093
P2860
P1433
P1476
Intron function in the nonsens ...... translation in the cytoplasm.
@en
P2093
P2860
P304
P356
10.1017/S1355838298971849
P407
P577
1998-07-01T00:00:00Z