Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. - Wikidata - awgldk - TriplyDB

Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres.

Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres.

http://www.wikidata.org/entity/Q34363706

about

Radioresistance of Brain Tumors ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state Motility of glioblastoma cells is driven by netrin-1 induced gain of stemness The inhibition of NOTCH2 reduces UVB-induced damage in retinal pigment epithelium cells.Inhibition of notch signaling in combination with Paclitaxel reduces platinum-resistant ovarian tumor growth.A novel anticancer therapy that simultaneously targets aberrant p53 and Notch activities in tumors Initial testing (stage 1) of the notch inhibitor PF-03084014, by the pediatric preclinical testing program.Short hairpin RNA targeting Notch2 inhibits U87 human glioma cell proliferation by inducing cell cycle arrest and apoptosis in vitro and in vivo.Notch signaling in serous ovarian cancer.Transdifferentiation of glioblastoma cells into vascular endothelial cells ASYMMETRIC CELL DIVISION: IMPLICATIONS FOR GLIOMA DEVELOPMENT AND TREATMENT.Not(ch) just development: Notch signalling in the adult brain.Novel therapies in glioblastoma.Role of hypoxia-related proteins in invasion of ameloblastoma cells: crosstalk between NOTCH1, hypoxia-inducible factor 1α, a disintegrin and metalloproteinase 12, and heparin-binding epidermal growth factor.Hes1: a key role in stemness, metastasis and multidrug resistance.Gastric tumor-initiating CD44(+) cells and epithelial-mesenchymal transition are inhibited by γ-secretase inhibitor DAPT Effects of Zeng Sheng Ping/ACAPHA on malignant brain tumor growth and Notch signaling.Epigallocatechin gallate inhibits the proliferation of colorectal cancer cells by regulating Notch signaling.PKCδ activated by c-MET enhances infiltration of human glioblastoma cells through NOTCH2 signaling.Prolonged inhibition of glioblastoma xenograft initiation and clonogenic growth following in vivo Notch blockade RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation.Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme.Targeting notch signaling pathway in cancer: clinical development advances and challenges STATus and Context within the Mammalian Nervous System.Role of Notch signalling pathway in cancer and its association with DNA methylation.Glioblastoma stem cells: Molecular characteristics and therapeutic implications Epigenetic pathways and glioblastoma treatment: insights from signaling cascades.Lateral inhibition of Notch signaling in neoplastic cells.Gamma-secretase inhibition attenuates oxaliplatin-induced apoptosis through increased Mcl-1 and/or Bcl-xL in human colon cancer cells.MicroRNA-107 inhibits U87 glioma stem cells growth and invasion.MicroRNA-107 inhibits glioma cell migration and invasion by modulating Notch2 expression.Human mesenchymal stem cell and epithelial hepatic carcinoma cell lines in admixture: concurrent stimulation of cancer-associated fibroblasts and epithelial-to-mesenchymal transition markers.The gamma secretase inhibitor MRK-003 attenuates pancreatic cancer growth in preclinical models.Interleukin-1β and transforming growth factor-β cooperate to induce neurosphere formation and increase tumorigenicity of adherent LN-229 glioma cells.Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1.Nanoparticles of carbon allotropes inhibit glioblastoma multiforme angiogenesis in ovo.Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers.Aberrant expression of Notch1, HES1, and DTX1 genes in glioblastoma formalin-fixed paraffin-embedded tissues.Molecular pathways: context-dependent approaches to Notch targeting as cancer therapy.IndividualizedPath: identifying genetic alterations contributing to the dysfunctional pathways in glioblastoma individuals.

P2860

Q26752579-E4A06492-1401-42DF-B0CD-42EF84CD58C4 Q28594320-75E6A8BD-3619-4077-BA84-6F6EBACFA205 Q30834482-0CCD8C73-4CE4-4CA2-BB81-6453EF8262F1 Q33828306-C3866C71-F805-496B-A6C0-6447AE480628 Q33851035-C7EE8747-004C-425F-8565-234B3A72813A Q34447293-9220B971-A620-4EE0-AB05-408921085174 Q34475754-C0936821-5083-4FB7-A176-8119C92EA3B1 Q34487956-21A507D9-E551-4577-AEE8-6ABC466BD281 Q34491211-CB62C1D5-FF04-496B-8C60-EA3CD751E5C4 Q34694093-BABEB9E9-BFF0-4F4C-86A6-D969FEF33C34 Q34723950-64A27948-4DBA-4ADE-AE23-9D805C4D193C Q35175155-5BC27F0A-BA4C-4B88-BF33-965884DAF6BF Q35864136-30AAF5AC-A1E3-4B67-B819-90C9C0CC9BCF Q35879045-647C05A5-7F8A-4910-88FA-602D31505DD1 Q36213706-19B57889-B197-4C6D-A264-B9104026090B Q36336218-990CB1C2-E407-48A2-815E-03C158DC0C45 Q36619107-BD7FB8AB-BDBC-4584-B100-E26FCEDDF393 Q36680241-648A5039-51CA-4636-B532-1AB14739AB4A Q36782617-92BFE2E0-0107-42F5-80FF-913A7107D7C3 Q36941324-5E3A3903-EFFA-4695-B2C6-082318F693D9 Q37042217-3AFDB420-4D8D-4BD4-8364-29BC04E27E7A Q37187681-BA0FA829-2687-449D-ADB2-DA571AC0C4DC Q37696748-02A95BB1-228F-43A9-9473-5A1D04291A2F Q37878907-6755388D-B34B-4D9B-8DE2-025E277D4FCE Q38174045-84DA1BC3-ABE7-4874-AC1C-A175EEF9D794 Q38207605-BBE46DD7-175C-433E-9EFD-40D7B7EE3A01 Q38257711-A0D756BC-D897-44FE-810F-E0A720E6ADA7 Q38923462-48FCAE93-4B2B-4BB2-BDA3-4ABE06490E2C Q39120190-61C07542-6D99-453A-B0DD-B23751CC3F40 Q39168771-31B6A669-75CC-44F3-8EF9-8BBDD005703B Q39214165-5AA404D1-7DC7-4F68-8123-0442C6CDB1D0 Q39287485-1F4561F9-02E9-4C5D-AA5A-F6D7109C4113 Q39321505-70587322-5B5F-43A4-A4F8-AA3B0782C8E2 Q39397148-B1EE01AB-2F35-4ABA-9342-133F1A33D3EF Q39411406-CA69511B-DC3C-45F2-A78B-CBC4F0AF8CB3 Q39429294-6C617B09-F846-4B50-B712-008EEFD23399 Q40008535-F9A7F890-E18A-4D22-9BAF-3C88B4940643 Q40216465-5FB1A3A7-7E9D-450C-B31C-50876672BFBC Q42531243-B839FA13-3211-493D-BDE6-86A238E522A0 Q45794856-84ADDC47-A987-4D8E-9C59-987EB842F9AB

P2860

Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres.

http://www.wikidata.org/entity/Q34363706

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年学术文章

@wuu

2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

@yue

name

Inhibition of notch signaling ...... lines and tumor neurospheres.

@ast

Inhibition of notch signaling ...... lines and tumor neurospheres.

@en

Inhibition of notch signaling ...... lines and tumor neurospheres.

@nl

type

label

Inhibition of notch signaling ...... lines and tumor neurospheres.

@ast

Inhibition of notch signaling ...... lines and tumor neurospheres.

@en

Inhibition of notch signaling ...... lines and tumor neurospheres.

@nl

prefLabel

Inhibition of notch signaling ...... lines and tumor neurospheres.

@ast

Inhibition of notch signaling ...... lines and tumor neurospheres.

@en

Inhibition of notch signaling ...... lines and tumor neurospheres.

@nl

P1433

Q34363706-91B9FFA4-03A7-4917-97E9-2F343BB83E5D

P1476

Q34363706-093B2E2F-5D81-45DA-AE5E-61F570676812

P2093

Q34363706-2A5D879B-36BA-47A5-A3E2-21CBCD01E2F2

Q34363706-4E58A9F0-85B3-44DC-9A1C-3FDEF8A6CCEB

Q34363706-7196A74C-C19B-4CA7-A787-5501A0B8A40D

Q34363706-75D0E7CC-1A9D-4CE4-A789-0BF1DDB2EA7F

Q34363706-8B15A41B-40F0-4B22-9914-7AED4FBC3B2D

Q34363706-9EA16D91-86D3-49E5-BC4D-C8E77FBBDB15

Q34363706-DAA80EA5-E99D-4D58-B08D-64C8107CED71

P2860

Q34363706-031819E6-5CA6-4463-974B-14B4AF7BDC67

Q34363706-08D89D9C-1B97-49A6-8567-F104D9E24A39

Q34363706-0AB67CA4-EC83-43CB-A481-B8BC3EEC7684

Q34363706-16501F01-3700-4898-B939-393B3634B894

Q34363706-167C2B71-9B9E-48EB-AC81-53024B38568B

Q34363706-178EDC87-6529-41B2-AF46-0FD28B14EDCA

Q34363706-19D414B0-883D-47E1-B523-1FCA224C5C2C

Q34363706-1F12910C-9113-4FC6-94C8-22604D9905AB

Q34363706-209D50B2-87E9-4623-81D4-E800C20ADB02

Q34363706-231A614C-CE37-4484-9E68-25E3A961F442

P304

Q34363706-B0B5D443-3775-4B3F-900A-FC0D3388938E

P31

Q34363706-9D454FEA-F6F1-44F5-B217-94345ABFE366

P356

Q34363706-ADB591AC-B29A-4C15-9D6F-50833F897CE9

P433

Q34363706-2AA47B65-2694-4E27-AFB6-248DEFA77512

P478

Q34363706-6B04F822-E29C-4B17-8A46-1DB7D5DAC88E

P50

Q34363706-5B558A06-8783-4964-8D0C-EE6C8AE92A30

P577

Q34363706-E9DDF059-A55F-4F8D-9C54-3E1EA142C986

P5875

Q34363706-C80DE874-DC15-431F-806F-BC2AA26AF913

P698

Q34363706-EFA0F7C3-BF71-4B57-87A7-EB439C36A5CF

P932

Q34363706-115E853F-5065-474C-B6ED-1CB486F5E5FF

P356

1947601910383564

P1433

P1476

Inhibition of notch signaling ...... l lines and tumor neurospheres

@en

P2093

Christine Rooney

http://www.w3.org/2001/XMLSchema#string

Huangxuan Shen

http://www.w3.org/2001/XMLSchema#string

James D Griffin

http://www.w3.org/2001/XMLSchema#string

Jie Chen

http://www.w3.org/2001/XMLSchema#string

Jihua Chen

http://www.w3.org/2001/XMLSchema#string

Lizi Wu

http://www.w3.org/2001/XMLSchema#string

Santosh Kesari

http://www.w3.org/2001/XMLSchema#string

P2860

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation

Direct inhibition of the NOTCH transcription factor complex

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Identification of human brain tumour initiating cells

Notch signaling: cell fate control and signal integration in development

Notch signalling regulates stem cell numbers in vitro and in vivo

Cyclin D1 is a nuclear protein required for cell cycle progression in G1

Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma

P304

822-835

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1177/1947601910383564

http://www.w3.org/2001/XMLSchema#string

P433

8

http://www.w3.org/2001/XMLSchema#string

P478

1

http://www.w3.org/2001/XMLSchema#string

P50

Peter R. Strack

P577

2010-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49654629

http://www.w3.org/2001/XMLSchema#string

P698

21127729

http://www.w3.org/2001/XMLSchema#string

P932

2994256

http://www.w3.org/2001/XMLSchema#string