Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner.
about
Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoproteinDistinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiationThe cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors.Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2.Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cellsA DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/MThe estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctionsPerinatal synthetic lethality and hematopoietic defects in compound mafG::mafK mutant miceErythro-megakaryocytic transcription factors associated with hereditary anemiaTranscription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosisRescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital developmentCorepressor Rcor1 is essential for murine erythropoiesisA lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development.Multiple, distant Gata2 enhancers specify temporally and tissue-specific patterning in the developing urogenital system.GATA2 is associated with familial early-onset coronary artery disease.A single cis element maintains repression of the key developmental regulator Gata2.FLI-1 inhibits differentiation and induces proliferation of primary erythroblasts.Impact of female cigarette smoking on circulating B cells in vivo: the suppressed ICOSLG, TCF3, and VCAM1 gene functional network may inhibit normal cell function.GATA-2 and GATA-2/ER display opposing activities in the development and differentiation of blood progenitors.Regulation of GATA-2 phosphorylation by mitogen-activated protein kinase and interleukin-3.Dynamic transcription factor activity profiles reveal key regulatory interactions during megakaryocytic and erythroid differentiationTranscription factor networks in erythroid cell and megakaryocyte developmentA GATA factor mediates cell type-restricted induction of HLA-E gene transcription by gamma interferon.GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodelingA GATA-2/estrogen receptor chimera functions as a ligand-dependent negative regulator of self-renewalAntagonism between C/EBPbeta and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitorsHistone demethylase LSD1-mediated repression of GATA-2 is critical for erythroid differentiationAndrogen-induced activation of gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) transcription: essential role of a nonclassical androgen response element half-site.GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cellsPositive regulators of the lineage-specific transcription factor GATA-1 in differentiating erythroid cells.Identification and functional characterization of an erythroid-specific enhancer in the L-type pyruvate kinase gene.GATA2 and Lmo2 control angiogenesis and lymphangiogenesis via direct transcriptional regulation of neuropilin-2.GATA-2 reinforces megakaryocyte development in the absence of GATA-1Leukemogenesis caused by incapacitated GATA-1 function.Nuclear translocation of a maternal CCAAT factor at the start of gastrulation activates Xenopus GATA-2 transcriptionA modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins.GATA elements are necessary for the activity and tissue specificity of the T-cell receptor beta-chain transcriptional enhancer.GATA-1-mediated transcriptional repression yields persistent transcription factor IIB-chromatin complexes.Eosinophil-specific regulation of gp91(phox) gene expression by transcription factors GATA-1 and GATA-2.Dynamic GATA factor interplay at a multicomponent regulatory region of the GATA-2 locus.
P2860
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P2860
Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner.
description
1993 nî lūn-bûn
@nan
1993 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Ectopic expression of a condit ...... in a hormone-dependent manner.
@ast
Ectopic expression of a condit ...... in a hormone-dependent manner.
@en
Ectopic expression of a condit ...... in a hormone-dependent manner.
@nl
type
label
Ectopic expression of a condit ...... in a hormone-dependent manner.
@ast
Ectopic expression of a condit ...... in a hormone-dependent manner.
@en
Ectopic expression of a condit ...... in a hormone-dependent manner.
@nl
prefLabel
Ectopic expression of a condit ...... in a hormone-dependent manner.
@ast
Ectopic expression of a condit ...... in a hormone-dependent manner.
@en
Ectopic expression of a condit ...... in a hormone-dependent manner.
@nl
P2093
P356
P1433
P1476
Ectopic expression of a condit ...... in a hormone-dependent manner
@en
P2093
P304
P356
10.1101/GAD.7.6.1097
P577
1993-06-01T00:00:00Z