Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands.
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Synthesis, structure-affinity relationships, and radiolabeling of selective high-affinity 5-HT4 receptor ligands as prospective imaging probes for positron emission tomographyImaging the cannabinoid CB1 receptor in humans with [11C]OMAR: assessment of kinetic analysis methods, test-retest reproducibility, and gender differences.Population-based input function modeling for [(18)F]FMPEP-d 2, an inverse agonist radioligand for cannabinoid CB1 receptors: validation in clinical studiesCannabinoid CB1 receptor immunoreactivity in the prefrontal cortex: Comparison of schizophrenia and major depressive disorder.A Review of Magnetic Resonance Spectroscopy Studies in Marijuana using Adolescents and Adults.Image-derived input function for human brain using high resolution PET imaging with [C](R)-rolipram and [C]PBR28Biodistribution and dosimetry in humans of two inverse agonists to image cannabinoid CB1 receptors using positron emission tomography.Reversible and regionally selective downregulation of brain cannabinoid CB1 receptors in chronic daily cannabis smokers.[¹²⁵I]SD-7015 reveals fine modalities of CB₁ cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer's diseaseIn vivo SPECT and ex vivo autoradiographic brain imaging of the novel selective CB1 receptor antagonist radioligand [125I]SD7015 in CB1 knock-out and wildtype mouse.Kinetic analysis in human brain of [11C](R)-rolipram, a positron emission tomographic radioligand to image phosphodiesterase 4: a retest study and use of an image-derived input function.Test-retest reproducibility of cannabinoid-receptor type 1 availability quantified with the PET ligand [¹¹C]MePPEP.N-(4-cyanotetrahydro-2H-pyran-4-yl) and N-(1-cyanocyclohexyl) derivatives of 1,5-diarylpyrazole-3-carboxamides showing high affinity for 18 kDa translocator protein and/or cannabinoid receptorsDecreased defluorination using the novel beta-cell imaging agent [18F]FE-DTBZ-d4 in pigs examined by PETRadiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofuran chemotype.Positron emission tomography shows elevated cannabinoid CB1 receptor binding in men with alcohol dependenceA PET study comparing receptor occupancy by five selective cannabinoid 1 receptor antagonists in non-human primates.Reduced cannabinoid CB1 receptor binding in alcohol dependence measured with positron emission tomography.11C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains.In vitro and in vivo evaluation of (11)C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors.Synthetic strategies for radioligands for in vivo imaging of brain cannabinoid type-1 receptors.Selective targeting of melanoma using N-(2-diethylaminoethyl) 4-[18F]fluoroethoxy benzamide (4-[18F]FEBZA): a novel PET imaging probe.Considerations in the Development of Reversibly Binding PET Radioligands for Brain Imaging.Radiolabeling and in vitro /in vivo evaluation of N-(1-adamantyl)-8-methoxy-4-oxo-1-phenyl-1,4-dihydroquinoline-3-carboxamide as a PET probe for imaging cannabinoid type 2 receptor.18F-MK-9470 PET imaging of the type 1 cannabinoid receptor in prostate carcinoma: a pilot study.Approaches to quantify radioligands that wash out slowly from target organsLow brain CB1 receptor occupancy by a second generation CB1 receptor antagonist TM38837 in comparison with rimonabant in nonhuman primates: a PET study.Acute induction of anxiety in humans by delta-9-tetrahydrocannabinol related to amygdalar cannabinoid-1 (CB1) receptors.Pharmacokinetics of the cannabinoid receptor ligand [18 F]MK-9470 in the rat brain - Evaluation of models using microPET.In vivo imaging of the cannabinoid CB1 receptor with positron emission tomography.Preclinical evaluation and quantification of [¹⁸F]MK-9470 as a radioligand for PET imaging of the type 1 cannabinoid receptor in rat brain.Automated one-step radiosynthesis of the CB1 receptor imaging agent [(18) F]MK-9470.
P2860
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P2860
Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Imaging and quantitation of ca ...... inverse agonist radioligands.
@ast
Imaging and quantitation of ca ...... inverse agonist radioligands.
@en
Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using
@nl
type
label
Imaging and quantitation of ca ...... inverse agonist radioligands.
@ast
Imaging and quantitation of ca ...... inverse agonist radioligands.
@en
Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using
@nl
prefLabel
Imaging and quantitation of ca ...... inverse agonist radioligands.
@ast
Imaging and quantitation of ca ...... inverse agonist radioligands.
@en
Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using
@nl
P2093
P2860
P921
P1476
Imaging and quantitation of ca ...... inverse agonist radioligands.
@en
P2093
Cheryl L Morse
Christian C Felder
Garth E Terry
Jeih-San Liow
Johannes T Tauscher
John M Schaus
Jussi Hirvonen
Lee Phebus
Robert B Innis
Robert Gladding
P2860
P304
P356
10.2967/JNUMED.109.067074
P407
P577
2009-12-15T00:00:00Z