Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand. - Wikidata - awgldk - TriplyDB

Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand.

Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand.

http://www.wikidata.org/entity/Q37316109

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Imaging the cannabinoid CB1 receptor in humans with [11C]OMAR: assessment of kinetic analysis methods, test-retest reproducibility, and gender differences.Molecular Imaging Markers to Track Huntington’s Disease Pathology Endocannabinoid signaling in the etiology and treatment of major depressive illness.Neuroimaging in Huntington's disease.Image-derived input function for human brain using high resolution PET imaging with [C](R)-rolipram and [C]PBR28 Biodistribution and dosimetry in humans of two inverse agonists to image cannabinoid CB1 receptors using positron emission tomography.[¹²⁵I]SD-7015 reveals fine modalities of CB₁ cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer's disease In vivo SPECT and ex vivo autoradiographic brain imaging of the novel selective CB1 receptor antagonist radioligand [125I]SD7015 in CB1 knock-out and wildtype mouse.Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands.Test-retest reproducibility of cannabinoid-receptor type 1 availability quantified with the PET ligand [¹¹C]MePPEP.N-(4-cyanotetrahydro-2H-pyran-4-yl) and N-(1-cyanocyclohexyl) derivatives of 1,5-diarylpyrazole-3-carboxamides showing high affinity for 18 kDa translocator protein and/or cannabinoid receptors Poorer frontolimbic white matter integrity is associated with chronic cannabis use, FAAH genotype, and increased depressive and apathy symptoms in adolescents and young adults Positron emission tomography shows elevated cannabinoid CB1 receptor binding in men with alcohol dependence Improved models for plasma radiometabolite correction and their impact on kinetic quantification in PET studies A PET study comparing receptor occupancy by five selective cannabinoid 1 receptor antagonists in non-human primates.Characterization of fast-decaying PET radiotracers solely through LC-MS/MS of constituent radioactive and carrier isotopologues.Mapping human brain fatty acid amide hydrolase activity with PET.In vitro and in vivo evaluation of (11)C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors.Retest imaging of [11C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in the brain of healthy humans.Impact of cannabis use on prefrontal and parietal cortex gyrification and surface area in adolescents and emerging adults.The impact of ADHD persistence, recent cannabis use, and age of regular cannabis use onset on subcortical volume and cortical thickness in young adults Rebinding: or why drugs may act longer in vivo than expected from their in vitro target residence time.Comorbid substance use disorder in schizophrenia: a selective overview of neurobiological and cognitive underpinnings.Cannabis, a complex plant: different compounds and different effects on individuals.Synthetic strategies for radioligands for in vivo imaging of brain cannabinoid type-1 receptors.Dyskinesias in Parkinson's disease: views from positron emission tomography studies.Involvement of the endocannabinoid system in reward processing in the human brain Guidelines to PET measurements of the target occupancy in the brain for drug development.Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase.PET Molecular Imaging Research of Levodopa-Induced Dyskinesias in Parkinson's Disease.18F-MK-9470 PET imaging of the type 1 cannabinoid receptor in prostate carcinoma: a pilot study.Approaches to quantify radioligands that wash out slowly from target organs Acute induction of anxiety in humans by delta-9-tetrahydrocannabinol related to amygdalar cannabinoid-1 (CB1) receptors.Pharmacokinetics of the cannabinoid receptor ligand [18 F]MK-9470 in the rat brain - Evaluation of models using microPET.[Carboxyl-11 C]Labelling of Four High-Affinity cPLA2α Inhibitors and Their Evaluation as Radioligands in Mice by Positron Emission Tomography.Using molecular imaging to understand early schizophrenia-related psychosis neurochemistry: a review of human studies.Preclinical evaluation and quantification of [¹⁸F]MK-9470 as a radioligand for PET imaging of the type 1 cannabinoid receptor in rat brain.Synthesis and preclinical evaluation of [¹⁸F]FCHC for neuroimaging of fatty acid amide hydrolase.Automated one-step radiosynthesis of the CB1 receptor imaging agent [(18) F]MK-9470.Small-animal PET imaging of the type 1 and type 2 cannabinoid receptors in a photothrombotic stroke model.

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Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand.

http://www.wikidata.org/entity/Q37316109

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 30 June 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Quantitation of cannabinoid CB ...... n inverse agonist radioligand.

@en

Quantitation of cannabinoid CB ...... n inverse agonist radioligand.

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type

label

Quantitation of cannabinoid CB ...... n inverse agonist radioligand.

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Quantitation of cannabinoid CB ...... n inverse agonist radioligand.

@nl

prefLabel

Quantitation of cannabinoid CB ...... n inverse agonist radioligand.

@en

Quantitation of cannabinoid CB ...... n inverse agonist radioligand.

@nl

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J.NEUROIMAGE.2009.06.059

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Alicja Lerner

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Amanda G Farris

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Cheryl L Morse

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Christian C Felder

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Garth E Terry

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Jeih-San Liow

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Jinsoo S Hong

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Johannes T Tauscher

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John M Schaus

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Jussi Hirvonen

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P2860

[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor

Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain

International Union of Pharmacology. XXVII. Classification of cannabinoid receptors

Reduced cortical cannabinoid 1 receptor messenger RNA and protein expression in schizophrenia

The PET radioligand [11C]MePPEP binds reversibly and with high specific signal to cannabinoid CB1 receptors in nonhuman primate brain.

Consensus nomenclature for in vivo imaging of reversibly binding radioligands.

Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents.

Isolation and expression of a mouse CB1 cannabinoid receptor gene. Comparison of binding properties with those of native CB1 receptors in mouse brain and N18TG2 neuroblastoma cells.

Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging.

Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain.

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