Tumor suppressor p53 represses transcription of RECQ4 helicase. - Wikidata - awgldk - TriplyDB

Tumor suppressor p53 represses transcription of RECQ4 helicase.

Tumor suppressor p53 represses transcription of RECQ4 helicase.

http://www.wikidata.org/entity/Q34388704

about

Rothmund-Thomson syndrome The transcription factor p53: not a repressor, solely an activator Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence RECQL4 in genomic instability and aging Transcriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptation p53 in the DNA-Damage-Repair Process p53 coordinates base excision repair to prevent genomic instability p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes.Redox regulation of DNA repair: implications for human health and cancer therapeutic development.Rare copy number variants observed in hereditary breast cancer cases disrupt genes in estrogen signaling and TP53 tumor suppression network p53 acts as a co-repressor to regulate keratin 14 expression during epidermal cell differentiation The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress.Human RecQL4 helicase plays critical roles in prostate carcinogenesis.Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis.Increased common fragile site expression, cell proliferation defects, and apoptosis following conditional inactivation of mouse Hus1 in primary cultured cells.APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.Epigenetic tête-à-tête: the bilateral relationship between chromatin modifications and DNA methylation.Versatile functions of p53 protein in multicellular organisms Protein methylation: a new mechanism of p53 tumor suppressor regulation.The Werner's syndrome 4330T>C (Cys1367Arg) gene variant does not affect the in vitro cytotoxicity of topoisomerase inhibitors and platinum compounds.Genetic and epigenetic alterations as biomarkers for cancer detection, diagnosis and prognosis.RecQ4: the second replicative helicase?One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor.Sp1 and the 'hallmarks of cancer'.Wild-type p53 and p73 negatively regulate expression of proliferation related genes.Census and evaluation of p53 target genes.p53 downregulates the Fanconi anaemia DNA repair pathway.Downstream and intermediate interactions of synovial sarcoma-associated fusion oncoproteins and their implication for targeted therapy.RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner.Hmga1 is differentially expressed and mediates silencing of the CD4/CD8 loci in T cell lineages and leukemic cells.

P2860

Q21202881-B270F283-EDF1-4F38-85A1-DB7EDF24B2FD Q24273295-49FDA7B8-122D-4A64-AB35-FB94713C821D Q24650175-6E983570-43CC-47E9-A79D-D384E50A46A2 Q26829765-C9C4F1EB-F222-4EA8-9668-03D635AFAB53 Q27026117-6EC6262A-D1A8-4EFF-9757-BFC4FD565C6A Q28073944-862BAA8B-9002-421D-9AEB-AC747B0852D6 Q28834500-809E2299-3337-402B-8DB4-46357A08C4B2 Q33794127-C745FB4D-C7F6-48B0-90DA-EDAD2ED406F2 Q33830130-647059D0-4C8B-4D85-AF30-9968557CF88D Q34318239-6A46C25A-D92E-4946-98FB-611D93F906E7 Q34388165-2FD09A88-CD7F-4EF0-A79E-947596E5CE23 Q34498861-4035FF51-0890-4D9A-B1BD-A9CE25A8C60A Q34684298-BCD9C8D7-D059-451B-8AF8-62570F4CC29A Q35095843-3CFB7425-D881-4C8C-B478-4A1AA5C07630 Q35650781-E15163D2-4945-47DA-A011-24DA4C3D894C Q35870045-15049C0F-C9F4-46BE-BD15-839CAF015B2C Q36579350-58A65CB3-E77A-475E-A6F9-3562B2B59A62 Q37087404-5118FE57-9BBA-4947-A1C4-D94B22558071 Q37200670-B1B5028A-4F9C-470F-92EF-C40669F830F6 Q37317528-63C85BAA-9A41-4274-BD47-44FEC000345D Q37453787-198D2247-612D-4D8A-A57F-4CBAD627EBBD Q37739460-92DBE5CF-D856-4298-A511-BF0E7DA560C6 Q37857673-A89819F1-5D60-4454-BE3B-692B23569AF1 Q38267908-6F1CE845-46EA-4E61-B153-113CCB434557 Q38296687-5E3DDD33-8566-4497-A21D-1A00E16F9678 Q38911126-E700FC68-8059-4F65-9FDE-ACF182EC6AF3 Q39897828-A21D65FA-4D70-4653-8E2A-38ADBFA31F5B Q41918438-08310C56-5D62-468E-A543-F001C0F3DD04 Q43089122-54DC4EE5-267A-4A6D-AF2D-2ECBEB2F38E0 Q44035793-19C7CF5A-B1A6-41B8-8FD1-CC0C59741BB4

P2860

Tumor suppressor p53 represses transcription of RECQ4 helicase.

http://www.wikidata.org/entity/Q34388704

description

2005 nî lūn-bûn

@nan

2005 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի մարտին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Tumor suppressor p53 represses transcription of RECQ4 helicase.

@ast

Tumor suppressor p53 represses transcription of RECQ4 helicase.

@en

Tumor suppressor p53 represses transcription of RECQ4 helicase.

@nl

type

label

Tumor suppressor p53 represses transcription of RECQ4 helicase.

@ast

Tumor suppressor p53 represses transcription of RECQ4 helicase.

@en

Tumor suppressor p53 represses transcription of RECQ4 helicase.

@nl

prefLabel

Tumor suppressor p53 represses transcription of RECQ4 helicase.

@ast

Tumor suppressor p53 represses transcription of RECQ4 helicase.

@en

Tumor suppressor p53 represses transcription of RECQ4 helicase.

@nl

P1433

Q34388704-B81FC8A6-45A5-445B-B63F-61DB05619DE9

P1476

Q34388704-CE6AA626-9073-4978-8EE3-D2F1F2B8B76A

P2093

Q34388704-0A0A55CB-F40C-4540-B428-9989A87EA887

Q34388704-27204FF2-6BEC-4D08-B4B3-5D418E6C0DC0

Q34388704-3270A801-24E8-4973-B681-AD1B9974D4A9

Q34388704-42456AC2-9A4A-4B4A-AFFA-D64CF8E668C2

Q34388704-4516A887-8747-4E87-9F2B-CB303CD8C428

Q34388704-84E7601B-52B5-47B0-A3EE-9210914464EB

Q34388704-A67BF491-B9ED-44C4-9450-EC9232E21600

Q34388704-A9F44FF0-D5D1-429F-9146-1FB4D6CDC33C

Q34388704-C5933F9F-DE75-41FD-A359-56F7D2E37999

Q34388704-D4E90419-DBD8-4018-A722-6022E23B7001

P2860

Q34388704-221EC94C-F04B-41C3-BD02-F6E3735A236D

Q34388704-5CB88627-497B-4B7A-A701-9704B07FCEF9

Q34388704-5D8198B4-A424-4AB9-A104-24B44F49BF53

Q34388704-658C1135-CD55-4D59-8C5D-BF8214784FE4

Q34388704-658F84B0-BA09-42AD-926B-159B20A33E8E

Q34388704-6CCBCD1D-1B6C-42A0-824D-BDC0098E465D

Q34388704-819AF41B-BC97-4FA6-B259-7D19B171D20B

Q34388704-85E54AE7-5CF7-4096-8199-5C6B75D5DD1B

Q34388704-8FFBC62C-D977-4F24-9D9E-5E17EF8FF541

Q34388704-98321DC6-946A-4AAB-B626-B8541F65457F

P2888

Q34388704-9F0C9783-60E1-48B5-8540-3E0D3DFCE264

P304

Q34388704-4DC9A358-2574-4AAB-B0F0-700DEBC13EF6

P31

Q34388704-B17AD45F-B5AF-46E5-A0CB-B6822B76967F

P356

Q34388704-FE95C9F5-05B6-4F1F-B58E-C8B8E98AB964

P407

Q34388704-19E50A30-EEF7-4763-8D8A-F13C7C3E8F72

P433

Q34388704-A5EC8927-0ABE-4C9D-AF9C-FCB0912F79DB

P478

Q34388704-7D194FC2-54FD-4A41-A314-4929E6125252

P577

Q34388704-725D458A-1269-4EE3-A378-E7B5DABE7671

P5875

Q34388704-B08FF313-5171-43B8-9D0E-BA849AF56024

P6179

Q34388704-566321C4-4D41-4F55-B1CA-B7D17A2D126D

P698

Q34388704-133A7DFF-E228-43D9-8667-52DA0C38ACCB

P356

P1433

P1476

Tumor suppressor p53 represses transcription of RECQ4 helicase.

@en

P2093

Akira Shimamoto

http://www.w3.org/2001/XMLSchema#string

Curtis C Harris

http://www.w3.org/2001/XMLSchema#string

Elisa A Spillare

http://www.w3.org/2001/XMLSchema#string

Jiang Cheng Shen

http://www.w3.org/2001/XMLSchema#string

L Eric Huang

http://www.w3.org/2001/XMLSchema#string

Marek Rusin

http://www.w3.org/2001/XMLSchema#string

Minori Koshiji

http://www.w3.org/2001/XMLSchema#string

Noralane M Lindor

http://www.w3.org/2001/XMLSchema#string

Remy Pedeux

http://www.w3.org/2001/XMLSchema#string

Sagar Sengupta

http://www.w3.org/2001/XMLSchema#string

P2860

SWI/SNF complex interacts with tumor suppressor p53 and is necessary for the activation of p53-mediated transcription

Wild-type p53 binds to the TATA-binding protein and represses transcription

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1

Functional interaction of p53 and BLM DNA helicase in apoptosis

Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product

Association between osteosarcoma and deleterious mutations in the RECQL4 gene in Rothmund-Thomson syndrome.

Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation.

p53: traffic cop at the crossroads of DNA repair and recombination.

Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks.

P2888

P304

1738-1748

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1208380

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

24

http://www.w3.org/2001/XMLSchema#string

P577

2005-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8058230

http://www.w3.org/2001/XMLSchema#string

P6179

1004007620

http://www.w3.org/2001/XMLSchema#string

P698

15674334

http://www.w3.org/2001/XMLSchema#string