Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models. - Wikidata - awgldk - TriplyDB

Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.

Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.

http://www.wikidata.org/entity/Q34391423

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P1343

Ovarian Cancer: The Fallopian Tube as the Site of Origin and Opportunities for Prevention Genetic and epigenetic heterogeneity of epithelial ovarian cancer and the clinical implications for molecular targeted therapy Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer Emerging and Evolving Ovarian Cancer Animal Models Single and Multiple Gene Manipulations in Mouse Models of Human Cancer Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk Salpingectomy as a means to reduce ovarian cancer risk The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids.Mutant p53 regulates ovarian cancer transformed phenotypes through autocrine matrix deposition.miR-200c Regulation of Metastases in Ovarian Cancer: Potential Role in Epithelial and Mesenchymal Transition The disparate origins of ovarian cancers: pathogenesis and prevention strategies.Rationale for Developing a Specimen Bank to Study the Pathogenesis of High-Grade Serous Carcinoma: A Review of the Evidence Advances in tumor screening, imaging, and avatar technologies for high-grade serous ovarian cancer.Chlamydia infection depends on a functional MDM2-p53 axis The ovary is an alternative site of origin for high-grade serous ovarian cancer in mice.Histones and their modifications in ovarian cancer - drivers of disease and therapeutic targets.Reliable in vitro studies require appropriate ovarian cancer cell lines Overexpression of CD47 predicts poor prognosis and promotes cancer cell invasion in high-grade serous ovarian carcinoma.MUC1 positive, Kras and Pten driven mouse gynecologic tumors replicate human tumors and vary in survival and nuclear grade based on anatomical location.Ovulation and extra-ovarian origin of ovarian cancer A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development.Threonyl-tRNA synthetase overexpression correlates with angiogenic markers and progression of human ovarian cancer Analysis of serial ovarian volume measurements and incidence of ovarian cancer: implications for pathogenesis.A Mouse Model That Reproduces the Developmental Pathways and Site Specificity of the Cancers Associated With the Human BRCA1 Mutation Carrier State Complement pathway is frequently altered in endometriosis and endometriosis-associated ovarian cancer Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier miR-145 inhibits tumor growth and metastasis by targeting metadherin in high-grade serous ovarian carcinoma Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling.Precursors of ovarian cancer in the fallopian tube: serous tubal intraepithelial carcinoma--an update.A role for PAX8 in the tumorigenic phenotype of ovarian cancer cells.Three-dimensional modeling of the human fallopian tube fimbriae Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS.Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer.Three-dimensional modeling of ovarian cancer.Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer Stromal Expression of Fibroblast Activation Protein Alpha (FAP) Predicts Platinum Resistance and Shorter Recurrence in patients with Epithelial Ovarian Cancer.Tubal origin of ovarian endometriosis and clear cell and endometrioid carcinoma.Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci.The promise and challenge of ovarian cancer models.Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

P2860

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P1343

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P2860

Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.

http://www.wikidata.org/entity/Q34391423

description

2013 nî lūn-bûn

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2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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Transformation of the fallopia ...... ncer in Brca;Tp53;Pten models.

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Transformation of the fallopia ...... ncer in Brca;Tp53;Pten models.

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Transformation of the fallopia ...... ncer in Brca;Tp53;Pten models.

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Transformation of the fallopia ...... ncer in Brca;Tp53;Pten models.

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Transformation of the fallopia ...... ncer in Brca;Tp53;Pten models.

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Transformation of the fallopia ...... ncer in Brca;Tp53;Pten models.

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Transformation of the fallopia ...... ncer in Brca;Tp53;Pten models.

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Alison M Karst

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Barish B Poole

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Christopher P Crum

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Corey D Stepule

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Daniela M Dinulescu

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Gregory A Wyant

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Jin Yun H Chen

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Jonathan G Bijron

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Katherine W Muto

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Kenneth T Chin

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P2860

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers.

Integrated genomic analyses of ovarian carcinoma

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Cancer statistics, 2012

Generalized lacZ expression with the ROSA26 Cre reporter strain

Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers

A comprehensive analysis of PAX8 expression in human epithelial tumors

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

Molecular requirements for transformation of fallopian tube epithelial cells into serous carcinoma.

A candidate precursor to serous carcinoma that originates in the distal fallopian tube.

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