Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.

Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.

Item
http://www.wikidata.org/entity/Q34397894
Bioactivation of dapsone to a cytotoxic metabolite: in vitro use of a novel two compartment system which contains human tissues.Carbamazepine-hypersensitivity: assessment of clinical and in vitro chemical cross-reactivity with phenytoin and oxcarbazepine.Dapsone hydroxylamine induces premature removal of human erythrocytes by membrane reorganization and antibody bindingIdiosyncratic drug reactions: a mechanistic evaluation of risk factorsDrug bioactivation, covalent binding to target proteins and toxicity relevance.Adverse drug effects: Part II.Dapsone: modes of action, toxicity and possible strategies for increasing patient tolerance.Studies on the toxicity of analogues of dapsone in-vitro using rat, human and heterologously expressed metabolizing systems.N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity.The use of cimetidine as a selective inhibitor of dapsone N-hydroxylation in man.The use of a three compartment in vitro model to investigate the role of hepatic drug metabolism in drug-induced blood dyscrasias.An investigation of the role of metabolism in dapsone-induced methaemoglobinaemia using a two compartment in vitro test system.Direct and metabolism-dependent toxicity of sulphasalazine and its principal metabolites towards human erythrocytes and leucocytes.Metabolism of ciamexon by human liver microsomes: an investigation into the formation of stable, chemically reactive and cytotoxic metabolites.Gonadal influence on the metabolism and haematological toxicity of dapsone in the rat.Mechanistic study on aniline-induced erythrocyte toxicity.Dapsone-induced agranulocytosis-possible involvement of low-activity N-acetyltransferase 2.
P2860

Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.

Item
http://www.wikidata.org/entity/Q34397894
description
1989 nî lūn-bûn
@nan
1989 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.
@ast
Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.
@en
Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.
@nl
type
label
Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.
@ast
Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.
@en
Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.
@nl
prefLabel
Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.
@ast
Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.
@en
Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.
@en
P2093
P2860
P304
P31
P356
10.1111/J.1365-2125.1989.TB03517.X
P407
P433
P478
P577
P5875
P698
P921
P932