An in vitro study of the microsomal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin.
about
Lymphocyte microsomal epoxide hydrolase in patients on carbamazepine therapy.Bioactivation of dapsone to a cytotoxic metabolite: in vitro use of a novel two compartment system which contains human tissues.Carbamazepine-hypersensitivity: assessment of clinical and in vitro chemical cross-reactivity with phenytoin and oxcarbazepine.A stereochemical investigation of the cytotoxicity of mianserin metabolites in vitro.Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes.Antidepressant-induced hepatotoxicity.Hepatic injury caused by mianserinAdverse drug effect-reactive metabolites and idiosyncratic drug reactions: Part I.Drug bioactivation, covalent binding to target proteins and toxicity relevance.Adverse drug effects: Part II.The role of leukocyte-generated reactive metabolites in the pathogenesis of idiosyncratic drug reactions.Using a simple HPLC approach to identify the enzymatic products of UTL-5g, a small molecule TNF-α inhibitor, from porcine esterase and from rabbit esteraseDrug-protein conjugation and its immunological consequences.In vitro analysis of metabolic predisposition to drug hypersensitivity reactions.Detection of an autoantibody directed against human liver microsomal protein in a patient with carbamazepine hypersensitivity.Pharmacokinetics of old, new, and yet-to-be-discovered antiepileptic drugs.The toxicity of amodiaquine and its principal metabolites towards mononuclear leucocytes and granulocyte/monocyte colony forming units.An investigation of the role of metabolism in dapsone-induced methaemoglobinaemia using a two compartment in vitro test system.Direct and metabolism-dependent toxicity of sulphasalazine and its principal metabolites towards human erythrocytes and leucocytes.Structural requirements for bioactivation of anticonvulsants to cytotoxic metabolites in vitro.Metabolism of ciamexon by human liver microsomes: an investigation into the formation of stable, chemically reactive and cytotoxic metabolites.Proceedings of the British Pharmacological Society, British Pharmacology Section. 18-20 April 1990, Sheffield. Abstracts
P2860
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P2860
An in vitro study of the microsomal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin.
description
1988 nî lūn-bûn
@nan
1988 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
An in vitro study of the micro ...... ytoin, sorbinil and mianserin.
@ast
An in vitro study of the micro ...... ytoin, sorbinil and mianserin.
@en
An in vitro study of the micro ...... ytoin, sorbinil and mianserin.
@nl
type
label
An in vitro study of the micro ...... ytoin, sorbinil and mianserin.
@ast
An in vitro study of the micro ...... ytoin, sorbinil and mianserin.
@en
An in vitro study of the micro ...... ytoin, sorbinil and mianserin.
@nl
prefLabel
An in vitro study of the micro ...... ytoin, sorbinil and mianserin.
@ast
An in vitro study of the micro ...... ytoin, sorbinil and mianserin.
@en
An in vitro study of the micro ...... ytoin, sorbinil and mianserin.
@nl
P2093
P2860
P1476
An in vitro study of the micro ...... ytoin, sorbinil and mianserin.
@en
P2093
N R Kitteringham
P2860
P304
P356
10.1111/J.1365-2125.1988.TB05298.X
P407
P577
1988-11-01T00:00:00Z