about
End-plate acetylcholine receptor: structure, mechanism, pharmacology, and diseaseSize matters in activation/inhibition of ligand-gated ion channelsDecrypting the sequence of structural events during the gating transition of pentameric ligand-gated ion channels based on an interpolated elastic network modelCrystal structure of a human GABAA receptorGalanthamine and Non-competitive Inhibitor Binding to ACh-binding Protein: Evidence for a Binding Site on Non-α-subunit Interfaces of Heteromeric Neuronal Nicotinic ReceptorsStructure of a potentially open state of a proton-activated pentameric ligand-gated ion channelX-ray structure of a pentameric ligand-gated ion channel in an apparently open conformationArginine residues at internal positions in a protein are always chargedA locally closed conformation of a bacterial pentameric proton-gated ion channelGating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallographyInhibition of the Human Respiratory Syncytial Virus Small Hydrophobic Protein and Structural Variations in a Bicelle EnvironmentAllosteric activation mechanism of the cys-loop receptorsRecent advances in Cys-loop receptor structure and functionIs arginine charged in a membrane?Energy and structure of the M2 helix in acetylcholine receptor-channel gating.Ion conduction through MscS as determined by electrophysiology and simulation.In silico models for the human alpha4beta2 nicotinic acetylcholine receptor.Ionization Properties of Histidine Residues in the Lipid Bilayer Membrane Environment.Targeted molecular dynamics study of C-loop closure and channel gating in nicotinic receptors.Gating at the mouth of the acetylcholine receptor channel: energetic consequences of mutations in the alphaM2-capIdentifying the elusive link between amino acid sequence and charge selectivity in pentameric ligand-gated ion channels.Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins.Multi-scale electrophysiology modeling: from atom to organSide-chain conformation at the selectivity filter shapes the permeation free-energy landscape of an ion channel.Chemical versus mechanical perturbations on the protonation state of arginine in complex lipid membranes: insights from microscopic pKa calculationsNicotinic acetylcholine receptor and the structural basis of neuromuscular transmission: insights from Torpedo postsynaptic membranesStructural answers and persistent questions about how nicotinic receptors work.Structure of the M2 transmembrane segment of GLIC, a prokaryotic Cys loop receptor homologue from Gloeobacter violaceus, probed by substituted cysteine accessibility.Energetic contributions to channel gating of residues in the muscle nicotinic receptor β1 subunit.Tunable pKa values and the basis of opposite charge selectivities in nicotinic-type receptorsDesensitization of alpha7 nicotinic receptor is governed by coupling strength relative to gate tightnessCorrelating structural and energetic changes in glycine receptor activation.Charge substitution for a deep-pore residue reveals structural dynamics during BK channel gating.Neutralization of a single arginine residue gates open a two-pore domain, alkali-activated K+ channelOn the thermodynamic stability of a charged arginine side chain in a transmembrane helixThe atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold.Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin.Nanosecond-timescale conformational dynamics of the human alpha7 nicotinic acetylcholine receptor.The small hydrophobic protein of the human respiratory syncytial virus forms pentameric ion channels.Gating-induced conformational rearrangement of the γ-aminobutyric acid type A receptor β-α subunit interface in the membrane-spanning domain
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Probing ion-channel pores one proton at a time.
@ast
Probing ion-channel pores one proton at a time.
@en
Probing ion-channel pores one proton at a time.
@nl
type
label
Probing ion-channel pores one proton at a time.
@ast
Probing ion-channel pores one proton at a time.
@en
Probing ion-channel pores one proton at a time.
@nl
prefLabel
Probing ion-channel pores one proton at a time.
@ast
Probing ion-channel pores one proton at a time.
@en
Probing ion-channel pores one proton at a time.
@nl
P2093
P2860
P356
P1433
P1476
Probing ion-channel pores one proton at a time.
@en
P2093
Claudio Grosman
Gisela D Cymes
P2860
P2888
P304
P356
10.1038/NATURE04293
P407
P577
2005-12-01T00:00:00Z
P5875
P6179
1024529350