Dlg1 binds GKAP to control dynein association with microtubules, centrosome positioning, and cell polarity.
about
Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modulesIdentification of mitogen-activated protein/extracellular signal-responsive kinase kinase 2 as a novel partner of the scaffolding protein human homolog of disc-largeRho GTPases at the crossroad of signaling networks in mammals: impact of Rho-GTPases on microtubule organization and dynamicsErbB2-dependent chemotaxis requires microtubule capture and stabilization coordinated by distinct signaling pathways.Protein kinase Cα promotes cell migration through a PDZ-dependent interaction with its novel substrate discs large homolog 1 (DLG1)Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin miceMicrotubule segment stabilization by RASSF1A is required for proper microtubule dynamics and Golgi integrity.Molecular mechanism of G1 arrest and cellular senescence induced by LEE011, a novel CDK4/CDK6 inhibitor, in leukemia cells.Crystallization and preliminary X-ray crystallographic analysis of the C-terminal domain of guanylate kinase-associated protein from Rattus norvegicus.Effects of dynein on microtubule mechanics and centrosome positioning.Cdc42 localization and cell polarity depend on membrane trafficMechanism of meningeal invasion by Neisseria meningitidisEmerging theme: cellular PDZ proteins as common targets of pathogenic viruses.Orientation and function of the nuclear-centrosomal axis during cell migration.Casein kinase I delta controls centrosome positioning during T cell activationThe Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network.RBFOX1 regulates both splicing and transcriptional networks in human neuronal development.Systems genetics implicates cytoskeletal genes in oocyte control of cloned embryo quality.Discs large 1 (Dlg1) scaffolding protein participates with clathrin and adaptator protein complex 1 (AP-1) in forming Weibel-Palade bodies of endothelial cells.Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation.Cytoplasmic dynein.Regulation of cell migration by dynamic microtubules.Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments.Shaping microtubules into diverse patterns: molecular connections for setting up both ends.Cell polarity as a regulator of cancer cell behavior plasticity.Emerging role of the scaffolding protein Dlg1 in vesicle trafficking.Orchestrating cytoskeleton and intracellular vesicle traffic to build functional immunological synapses.Centrosome positioning in non-dividing cells.The DLGAP family: neuronal expression, function and role in brain disorders.Regulation of microtubule-associated motors drives intermediate filament network polarization.Activation of Discs large by aPKC aligns the mitotic spindle to the polarity axis during asymmetric cell division.Evolutionary origin of synapses and neurons - Bridging the gap.Intermediate filaments join the action.Matrix rigidity regulates microtubule network polarization in migration.
P2860
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P2860
Dlg1 binds GKAP to control dynein association with microtubules, centrosome positioning, and cell polarity.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Dlg1 binds GKAP to control dyn ...... ositioning, and cell polarity.
@ast
Dlg1 binds GKAP to control dyn ...... ositioning, and cell polarity.
@en
Dlg1 binds GKAP to control dyn ...... ositioning, and cell polarity.
@nl
type
label
Dlg1 binds GKAP to control dyn ...... ositioning, and cell polarity.
@ast
Dlg1 binds GKAP to control dyn ...... ositioning, and cell polarity.
@en
Dlg1 binds GKAP to control dyn ...... ositioning, and cell polarity.
@nl
prefLabel
Dlg1 binds GKAP to control dyn ...... ositioning, and cell polarity.
@ast
Dlg1 binds GKAP to control dyn ...... ositioning, and cell polarity.
@en
Dlg1 binds GKAP to control dyn ...... ositioning, and cell polarity.
@nl
P2860
P356
P1476
Dlg1 binds GKAP to control dyn ...... positioning, and cell polarity
@en
P2093
Muguette Jehanno
P2860
P304
P356
10.1083/JCB.201002151
P407
P577
2010-11-01T00:00:00Z