SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors - Wikidata - awgldk - TriplyDB

SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors

SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors

http://www.wikidata.org/entity/Q34413881

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SDHA mutations causing a multisystem mitochondrial disease: novel mutations and genetic overlap with hereditary tumors Syndromic gastrointestinal stromal tumors SDHAF4 promotes mitochondrial succinate dehydrogenase activity and prevents neurodegeneration.Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial.Paragangliomas/Pheochromocytomas: clinically oriented genetic testing SDHA related tumorigenesis: a new case series and literature review for variant interpretation and pathogenicity.Succinate dehydrogenase deficient gastrointestinal stromal tumors (GISTs) - a review.Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST).Gastrointestinal stromal tumor - an evolving concept.Impact of age and gender on tumor related prognosis in gastrointestinal stromal tumors (GIST).Unique case of sporadic multiple gastro intestinal stromal tumour.Association of high expression of Groβ with clinical and pathological characteristics of unfavorable prognosis in gastrointestinal stromal tumors.Extended adjuvant therapy with imatinib in patients with gastrointestinal stromal tumors : recommendations for patient selection, risk assessment, and molecular response monitoring.Succinate dehydrogenase deficiency in pediatric and adult gastrointestinal stromal tumors.Gastrointestinal stromal tumors: management of metastatic disease and emerging therapies.Analysis of all subunits, SDHA, SDHB, SDHC, SDHD, of the succinate dehydrogenase complex in KIT/PDGFRA wild-type GIST.Alpha-Ketoglutarate as a Molecule with Pleiotropic Activity: Well-Known and Novel Possibilities of Therapeutic Use An overview on molecular biology of KIT/PDGFRA wild type (WT) gastrointestinal stromal tumours (GIST).Gastrointestinal stromal tumors: what do we know now?Oncometabolites-driven tumorigenesis: From genetics to targeted therapy.Toward an improved definition of the genetic and tumor spectrum associated with SDH germ-line mutations.The emerging role and targetability of the TCA cycle in cancer metabolism.Biochemical, Molecular, and Clinical Characterization of Succinate Dehydrogenase Subunit A Variants of Unknown Significance.The Assembly Factor SDHAF2 Is Dispensable for Flavination of the Catalytic Subunit of Mitochondrial Complex II in Breast Cancer Cells.A MUTYH germline mutation is associated with small intestinal neuroendocrine tumors.Succinate dehydrogenase deficiency in a PDGFRA mutated GIST.Chinese consensus guidelines for diagnosis and management of gastrointestinal stromal tumor.Succinate dehydrogenase deficiency is associated with decreased 5-hydroxymethylcytosine production in gastrointestinal stromal tumors: implications for mechanisms of tumorigenesis.SDHB/SDHA immunohistochemistry in pheochromocytomas and paragangliomas: a multicenter interobserver variation analysis using virtual microscopy: a Multinational Study of the European Network for the Study of Adrenal Tumors (ENS@T).Good survival outcome of metastatic SDH-deficient gastrointestinal stromal tumors harboring SDHA mutations.Response to correspondence: An immunohistochemical study of potential diagnostic and therapeutic biomarkers of wild-type gastrointestinal stromal tumours.

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SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors

http://www.wikidata.org/entity/Q34413881

description

2012 nî lūn-bûn

@nan

2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

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2012年論文

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2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

SDHA loss of function mutation ...... astrointestinal stromal tumors

@ast

SDHA loss of function mutation ...... astrointestinal stromal tumors

@en

SDHA loss of function mutation ...... astrointestinal stromal tumors

@nl

type

label

SDHA loss of function mutation ...... astrointestinal stromal tumors

@ast

SDHA loss of function mutation ...... astrointestinal stromal tumors

@en

SDHA loss of function mutation ...... astrointestinal stromal tumors

@nl

prefLabel

SDHA loss of function mutation ...... astrointestinal stromal tumors

@ast

SDHA loss of function mutation ...... astrointestinal stromal tumors

@en

SDHA loss of function mutation ...... astrointestinal stromal tumors

@nl

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SDHA loss of function mutation ...... astrointestinal stromal tumors

@en

P2093

Antoine Italiano

http://www.w3.org/2001/XMLSchema#string

Chun-Liang Chen

http://www.w3.org/2001/XMLSchema#string

Cristina R Antonescu

http://www.w3.org/2001/XMLSchema#string

Michael P LaQuaglia

http://www.w3.org/2001/XMLSchema#string

Nicholas Socci

http://www.w3.org/2001/XMLSchema#string

Peter Besmer

http://www.w3.org/2001/XMLSchema#string

Ronald P DeMatteo

http://www.w3.org/2001/XMLSchema#string

Yun-Shao Sung

http://www.w3.org/2001/XMLSchema#string

P2860

Leigh syndrome caused by mutations in the flavoprotein (Fp) subunit of succinate dehydrogenase (SDHA)

Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency

SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma

On the Origin of Cancer Cells

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

A role for mitochondrial enzymes in inherited neoplasia and beyond

Immunohistochemistry for SDHB divides gastrointestinal stromal tumors (GISTs) into 2 distinct types

Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

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1471-2407-12-408

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