Recent Development of Bifunctional Small Molecules to Study Metal-Amyloid-β Species in Alzheimer's Disease
about
Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal CompoundsRational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease.Design of small molecules that target metal-A{beta} species and regulate metal-induced A{beta} aggregation and neurotoxicity.Synthetic Flavonoids, Aminoisoflavones: Interaction and Reactivity with Metal-Free and Metal-Associated Amyloid-β SpeciesMisfolded proteins in Alzheimer's disease and type II diabetes.Reactivity of diphenylpropynone derivatives toward metal-associated amyloid-β species.Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-β speciesClawing back: broadening the notion of metal chelators in medicineExploring the reactivity of flavonoid compounds with metal-associated amyloid-β species.Small bifunctional chelators that do not disaggregate amyloid β fibrils exhibit reduced cellular toxicity.Bimodal-hybrid heterocyclic amine targeting oxidative pathways and copper mis-regulation in Alzheimer's disease.Neuroprotective peptide-macrocycle conjugates reveal complex structure-activity relationships in their interactions with amyloid β.Development of bifunctional stilbene derivatives for targeting and modulating metal-amyloid-β species.A potent antioxidant small molecule aimed at targeting metal-based oxidative stress in neurodegenerative disorders.An N-heterocyclic amine chelate capable of antioxidant capacity and amyloid disaggregation.Bifunctional compounds for controlling metal-mediated aggregation of the aβ42 peptide.Coordination Chemistry of Bifunctional Chemical Agents Designed for Applications in 64Cu PET Imaging for Alzheimer's Disease.Insight into inhibition of the human amyloid beta protein precursor (APP: PDB ID ) using (E)-N-(pyridin-2-ylmethylene)arylamine (LR) models: structure elucidation of a family of ZnX2-LR complexes.Synthesis and characterization of IMPY derivatives that regulate metal-induced amyloid-β aggregation.Azo-dyes based small bifunctional molecules for metal chelation and controlling amyloid formation
P2860
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P2860
Recent Development of Bifunctional Small Molecules to Study Metal-Amyloid-β Species in Alzheimer's Disease
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2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Recent Development of Bifuncti ...... Species in Alzheimer's Disease
@ast
Recent Development of Bifuncti ...... Species in Alzheimer's Disease
@en
Recent Development of Bifuncti ...... Species in Alzheimer's Disease
@nl
type
label
Recent Development of Bifuncti ...... Species in Alzheimer's Disease
@ast
Recent Development of Bifuncti ...... Species in Alzheimer's Disease
@en
Recent Development of Bifuncti ...... Species in Alzheimer's Disease
@nl
prefLabel
Recent Development of Bifuncti ...... Species in Alzheimer's Disease
@ast
Recent Development of Bifuncti ...... Species in Alzheimer's Disease
@en
Recent Development of Bifuncti ...... Species in Alzheimer's Disease
@nl
P2093
P2860
P356
P1476
Recent Development of Bifuncti ...... Species in Alzheimer's Disease
@en
P2093
Alaina S Detoma
Joseph J Braymer
Jung-Suk Choi
Kristin S Ko
Mi Hee Lim
P2860
P304
P356
10.4061/2011/623051
P577
2010-12-08T00:00:00Z