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Myofilament Calcium Sensitivity: Role in Regulation of In vivo Cardiac Contraction and RelaxationAutomated analysis of contractile force and Ca2+ transients in engineered heart tissue.Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates.Decrease in sarcoplasmic reticulum calcium content, not myofilament function, contributes to muscle twitch force decline in isolated cardiac trabeculae.The positive inotropic effect of pyruvate involves an increase in myofilament calcium sensitivity.Cardiac troponin I Pro82Ser variant induces diastolic dysfunction, blunts β-adrenergic response, and impairs myofilament cooperativityThe Ca2+/Mg2+ sites of troponin C modulate crossbridge-mediated thin filament activation in cardiac myofibrils.A novel electrocardiographic index for the diagnosis of diastolic dysfunctionEffects of increased systolic Ca²⁺ and phospholamban phosphorylation during β-adrenergic stimulation on Ca²⁺ transient kinetics in cardiac myocytes.Contractile strength during variable heart duration is species and preload dependent.Improvement of cardiac contractile function by peptide-based inhibition of NF-κB in the utrophin/dystrophin-deficient murine model of muscular dystrophy.Dissociation of Calcium Transients and Force Development following a Change in Stimulation Frequency in Isolated Rabbit MyocardiumThe interaction of Ca2+ with sarcomeric proteins: role in function and dysfunction of the heartStaurosporine inhibits frequency-dependent myofilament desensitization in intact rabbit cardiac trabeculae.Effects of increased preload on the force-frequency response and contractile kinetics in early stages of cardiac muscle hypertrophyThe Frank-Starling mechanism involves deceleration of cross-bridge kinetics and is preserved in failing human right ventricular myocardium.Effect of muscle length on cross-bridge kinetics in intact cardiac trabeculae at body temperatureIsolated neonatal rat papillary muscles: a new model to translate neonatal rat myocyte signaling into contractile mechanics.Post-translational modifications of myofilament proteins involved in length-dependent prolongation of relaxation in rabbit right ventricular myocardiumEffect of exercise training and myocardial infarction on force development and contractile kinetics in isolated canine myocardium.N-Glycolylneuraminic acid deficiency worsens cardiac and skeletal muscle pathophysiology in α-sarcoglycan-deficient miceDiscrete effects of A57G-myosin essential light chain mutation associated with familial hypertrophic cardiomyopathyCaMKII effects on inotropic but not lusitropic force frequency responses require phospholamban.Electromechanical coupling in the cardiac myocyte; stretch-arrhythmia feedback.Maladaptive modifications in myofilament proteins and triggers in the progression to heart failure and sudden death.Tri-modal regulation of cardiac muscle relaxation; intracellular calcium decline, thin filament deactivation, and cross-bridge cycling kinetics.Designing proteins to combat disease: Cardiac troponin C as an example.Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation.Cardiac Catheterization in Mice to Measure the Pressure Volume Relationship: Investigating the Bowditch Effect.Multiphysics model of a rat ventricular myocyte: a voltage-clamp study.The quest for load-independent left ventricular chamber properties: Exploring the normalized pressure phase plane.Rate-dependent Ca2+ signalling underlying the force-frequency response in rat ventricular myocytes: a coupled electromechanical modeling study.Acute volume loading exacerbates direct ventricular interaction in a model of COPD.Interaction between left ventricular twist mechanics and arterial haemodynamics during localised, non-metabolic hyperaemia with and without blood flow restriction.Stabilizing control for a pulsatile cardiovascular mathematical model.Noninvasive assessment of autonomic function in human neonates born at the extremes of fetal growth spectrum.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Myocardial contraction-relaxation coupling
@ast
Myocardial contraction-relaxation coupling
@en
Myocardial contraction-relaxation coupling
@nl
type
label
Myocardial contraction-relaxation coupling
@ast
Myocardial contraction-relaxation coupling
@en
Myocardial contraction-relaxation coupling
@nl
prefLabel
Myocardial contraction-relaxation coupling
@ast
Myocardial contraction-relaxation coupling
@en
Myocardial contraction-relaxation coupling
@nl
P2860
P1476
Myocardial contraction-relaxation coupling
@en
P2093
Paul M L Janssen
P2860
P304
P356
10.1152/AJPHEART.00759.2010
P577
2010-09-17T00:00:00Z