about
The genetics of dyskeratosis congenitaSolution structure and dynamics of the wild-type pseudoknot of human telomerase RNAA human-Tetrahymena pseudoknot chimeric telomerase RNA reconstitutes a nonprocessive enzyme in vitro that is defective in telomere elongationThe solution structure of an essential stem-loop of human telomerase RNAYNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA.Structurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNAPyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivoA single-molecule assay for telomerase structure-function analysisSingle-molecule fluorescence resonance energy transfer studies of the human telomerase RNA pseudoknot: temperature-/urea-dependent folding kinetics and thermodynamics.Predicting loop-helix tertiary structural contacts in RNA pseudoknots.Entropic stabilization of the folded states of RNA due to macromolecular crowdingSingle-molecule fluorescence coincidence spectroscopy and its application to resonance energy transfer.Evaluation of the conformational switch model for alfalfa mosaic virus RNA replication.Functional analysis of the pseudoknot structure in human telomerase RNA.RNA pseudoknots: folding and finding.Ribonucleoprotein multimers and their functions.Architecture of human telomerase RNA.Analysis of a long-range interaction between conserved domains of human telomerase RNA.Conformational analysis of the telomerase RNA pseudoknot hairpin by Raman spectroscopyFunctional importance of telomerase pseudoknot revealed by single-molecule analysis.A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase.A novel pseudoknot element is essential for the action of a yeast telomerase.Single-molecule mechanical unfolding and folding of a pseudoknot in human telomerase RNA.Pseudoknot structures with conserved base triples in telomerase RNAs of ciliatesRNA folding: conformational statistics, folding kinetics, and ion electrostatics.Retrotransposon Ty1 RNA contains a 5'-terminal long-range pseudoknot required for efficient reverse transcription.TERC and TERT gene mutations in patients with bone marrow failure and the significance of telomere length measurements.Discovery of ligands for a novel target, the human telomerase RNA, based on flexible-target virtual screening and NMR.Predicting structures and stabilities for H-type pseudoknots with interhelix loops.Structural conservation in the template/pseudoknot domain of vertebrate telomerase RNA from teleost fish to humanStructural elements required for association of the Saccharomyces cerevisiae telomerase RNA with the Est2 reverse transcriptase.Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice.Human telomerase expression regulation.Different role of functional domains of hTR in DNA binding to telomere and telomerase reconstruction.Single-Molecule Studies of Telomeres and Telomerase.Comprehensive structure-function analysis of the core domain of human telomerase RNA.Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA.Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer.Biphasic folding kinetics of RNA pseudoknots and telomerase RNA activity.Single-molecule FRET reveals the folding dynamics of the human telomerase RNA pseudoknot domain.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A molecular switch underlies a human telomerase disease
@ast
A molecular switch underlies a human telomerase disease
@en
A molecular switch underlies a human telomerase disease
@nl
type
label
A molecular switch underlies a human telomerase disease
@ast
A molecular switch underlies a human telomerase disease
@en
A molecular switch underlies a human telomerase disease
@nl
prefLabel
A molecular switch underlies a human telomerase disease
@ast
A molecular switch underlies a human telomerase disease
@en
A molecular switch underlies a human telomerase disease
@nl
P2093
P2860
P356
P1476
A molecular switch underlies a human telomerase disease
@en
P2093
Ivan Smirnov
Luis R Comolli
Thomas L James
P2860
P304
16998-17003
P356
10.1073/PNAS.262663599
P407
P577
2002-12-13T00:00:00Z