Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice.
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Vault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivoTelomerase modulates Wnt signalling by association with target gene chromatinHaploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenitaThe telomere syndromesHigh incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegansTelomeres and telomerase as therapeutic targets to prevent and treat age-related diseasesCellular mechanisms of tissue fibrosis. 7. New insights into the cellular mechanisms of pulmonary fibrosisInhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13pShort Telomeres in Key Tissues Initiate Local and Systemic Aging in ZebrafishVariation at the TERT locus and predisposition for cancerMouse dyskerin mutations affect accumulation of telomerase RNA and small nucleolar RNA, telomerase activity, and ribosomal RNA processingmRNA decay factor AUF1 maintains normal aging, telomere maintenance, and suppression of senescence by activation of telomerase transcriptionMurine Pif1 interacts with telomerase and is dispensable for telomere function in vivoLow abundance of telomerase in yeast: implications for telomerase haploinsufficiency.Dyskerin is a component of the Arabidopsis telomerase RNP required for telomere maintenance.Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic developmentA non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis.FANCC suppresses short telomere-initiated telomere sister chromatid exchangeSyndromes of telomere shorteningTelomerase deficiency does not alter bleomycin-induced fibrosis in miceThe telomerase reverse transcriptase regulates chromatin state and DNA damage responses.An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres.Mammographic density, blood telomere length and lipid peroxidationDissociation of telomerase activity and telomere length maintenance in primitive human hematopoietic cells.The effect of TERC haploinsufficiency on the inheritance of telomere length.Telomere dysfunction induces metabolic and mitochondrial compromise.Differential cis-regulation of human versus mouse TERT gene expression in vivo: identification of a human-specific repressive element.Telomerase is required for zebrafish lifespan.Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptaseProlonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cellsDoes the reservoir for self-renewal stem from the ends?Triallelic and epigenetic-like inheritance in human disorders of telomerase.In vivo regulation of telomerase activity and telomere length.3'-Azido-2',3'-dideoxynucleoside 5'-triphosphates inhibit telomerase activity in vitro, and the corresponding nucleosides cause telomere shortening in human HL60 cells.High telomerase is a hallmark of undifferentiated spermatogonia and is required for maintenance of male germline stem cells.Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivoEngineered telomere degradation models dyskeratosis congenitaTelomeres, a busy platform for cell signaling.Telomerase-dependent and -independent chromosome healing in mouse embryonic stem cells
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Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 April 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Distinct dosage requirements f ...... es in mTert heterozygous mice.
@en
Distinct dosage requirements f ...... es in mTert heterozygous mice.
@nl
type
label
Distinct dosage requirements f ...... es in mTert heterozygous mice.
@en
Distinct dosage requirements f ...... es in mTert heterozygous mice.
@nl
prefLabel
Distinct dosage requirements f ...... es in mTert heterozygous mice.
@en
Distinct dosage requirements f ...... es in mTert heterozygous mice.
@nl
P2093
P2860
P356
P1476
Distinct dosage requirements f ...... es in mTert heterozygous mice.
@en
P2093
Lea Harrington
Natalie Erdmann
P2860
P304
P356
10.1073/PNAS.0401580101
P407
P577
2004-04-12T00:00:00Z