A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status
about
FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformationThe secreted protein S100A7 (psoriasin) is induced by telomere dysfunction in human keratinocytes independently of a DNA damage response and cell cycle regulatorsFOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinomaCDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanismsGrainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytesImmortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathwayAlpha-actinin binding kinetics modulate cellular dynamics and force generationControl of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASGInitiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complexDoes Notch play a tumor suppressor role across diverse squamous cell carcinomas?Immortalization of Primary Keratinocytes and Its Application to Skin ResearchSelf-organized centripetal movement of corneal epithelium in the absence of external cues.Exploiting FOXM1-orchestrated molecular network for early squamous cell carcinoma diagnosis and prognosisHuman BAT possesses molecular signatures that resemble beige/brite cellsInk4a/Arf expression is a biomarker of agingHuman keratinocytes are efficiently immortalized by a Rho kinase inhibitorHuman papillomavirus E6 regulates the cytoskeleton dynamics of keratinocytes through targeted degradation of p53A keratinocyte hypermotility/growth-arrest response involving laminin 5 and p16INK4A activated in wound healing and senescence.Blueberry consumption prevents loss of collagen in bone matrix and inhibits senescence pathways in osteoblastic cells.HPV16 E7 protein and hTERT proteins defective for telomere maintenance cooperate to immortalize human keratinocytesFlagellin-induced corneal antimicrobial peptide production and wound repair involve a novel NF-kappaB-independent and EGFR-dependent pathway.Characterization of partially lifted cell sheets.p35 is required for CDK5 activation in cellular senescence.Culture, immortalization, and characterization of human meibomian gland epithelial cells.Creating oral squamous cancer cells: a cellular model of oral-esophageal carcinogenesis.Immortalization of oral keratinocytes by functional inactivation of the p53 and pRb pathways.A metalloproteinase secreted by Streptococcus pneumoniae removes membrane mucin MUC16 from the epithelial glycocalyx barrierGenome-wide chromatin state transitions associated with developmental and environmental cues.Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling.Radiation induces diffusible feeder cell factor(s) that cooperate with ROCK inhibitor to conditionally reprogram and immortalize epithelial cells.Differential effects of lovastatin on cisplatin responses in normal human mesothelial cells versus cancer cells: implication for therapy.Immortalized keratinocyte lines derived from human embryonic stem cellsStarvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatinOral epithelial cell responses to multispecies microbial biofilms.Effect of retinoic acid on gene expression in human conjunctival epithelium: secretory phospholipase A2 mediates retinoic acid induction of MUC16.Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetyAbolition of cyclin-dependent kinase inhibitor p16Ink4a and p21Cip1/Waf1 functions permits Ras-induced anchorage-independent growth in telomerase-immortalized human fibroblasts.Activation of the δ-opioid receptor promotes cutaneous wound healing by affecting keratinocyte intercellular adhesion and migrationEvaluation of single-cell biomechanics as potential marker for oral squamous cell carcinomas: a pilot study.
P2860
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P1343
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P2860
A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A two-stage, p16(INK4A)- and p ...... independent of telomere status
@ast
A two-stage, p16(INK4A)- and p ...... independent of telomere status
@en
A two-stage, p16(INK4A)- and p ...... independent of telomere status
@nl
type
label
A two-stage, p16(INK4A)- and p ...... independent of telomere status
@ast
A two-stage, p16(INK4A)- and p ...... independent of telomere status
@en
A two-stage, p16(INK4A)- and p ...... independent of telomere status
@nl
prefLabel
A two-stage, p16(INK4A)- and p ...... independent of telomere status
@ast
A two-stage, p16(INK4A)- and p ...... independent of telomere status
@en
A two-stage, p16(INK4A)- and p ...... independent of telomere status
@nl
P2093
P2860
P1476
A two-stage, p16(INK4A)- and p ...... independent of telomere status
@en
P2093
Caterina Catricalà
Hensin Tsao
James G Rheinwald
Jenny Y Wu
Kathleen M O'Toole
Michele De Luca
William C Hahn
Zongyou Guo
P2860
P304
P356
10.1128/MCB.22.14.5157-5172.2002
P407
P577
2002-07-01T00:00:00Z