AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27. - Wikidata - awgldk - TriplyDB

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

http://www.wikidata.org/entity/Q34447043

about

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS AMPK as a metabolic tumor suppressor: control of metabolism and cell growth.Proceedings from theNational Institute of Child Health and Human Development conference on the Uterine Fibroid Research Update Workshop.Lymphangioleiomyomatosis (LAM): molecular insights lead to targeted therapies.A novel germline CDKN1B mutation causing multiple endocrine tumors: clinical, genetic and functional characterization.Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade cAMP-dependent cytosolic mislocalization of p27(kip)-cyclin D1 during quinol-thioether-induced tuberous sclerosis renal cell carcinoma AMP-activated protein kinase restricts IFN-γ signaling.Loss of TSC2 confers resistance to ceramide and nutrient deprivation.Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I.The role of LKB1 and AMPK in cellular responses to stress and damage.Rheb signaling and tumorigenesis: mTORC1 and new horizons.Functional characterization of AMP-activated protein kinase signaling in tumorigenesis.Rheb promotes cancer cell survival through p27Kip1-dependent activation of autophagy.Plant SnRK1 Kinases: Structure, Regulation, and Function.Consequences of interrupted Rheb-to-AMPK feedback signaling in tuberous sclerosis complex and cancer.Apigenin, a chemopreventive bioflavonoid, induces AMP-activated protein kinase activation in human keratinocytes.AMPK-mediated phosphorylation of murine p27 at T197 promotes binding of 14-3-3 proteins and increases p27 stability.Depletion of p18/LAMTOR1 promotes cell survival via activation of p27(kip1) -dependent autophagy under starvation.Mitochondrial oligomers boost glycolysis in cancer stem cells to facilitate blebbishield-mediated transformation after apoptosis.Regulation of autophagy by glucose in Mammalian cells.Phosphorylation of p27(KIP1) homologs KRP6 and 7 by SNF1-related protein kinase-1 links plant energy homeostasis and cell proliferation.Cytoplasmic p27 is oncogenic and cooperates with Ras both in vivo and in vitro.PTEN/Akt-p27(kip1) Signaling Promote the BM-MSCs Senescence and Apoptosis in SLE Patients.Beneficial Effects of AMP-Activated Protein Kinase Agonists in Kidney Ischemia-Reperfusion: Autophagy and Cellular Stress Markers.

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AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

http://www.wikidata.org/entity/Q34447043

description

2008 nî lūn-bûn

@nan

2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

@ast

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

@en

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

@nl

type

label

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

@ast

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

@en

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

@nl

prefLabel

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

@ast

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

@en

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

@nl

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0008-5472.CAN-07-5756

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Cancer Research

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AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

@en

P2093

Charles L Johnson

http://www.w3.org/2001/XMLSchema#string

Cheryl Lyn Walker

http://www.w3.org/2001/XMLSchema#string

David Kwiatkowski

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Fuyuhiko Tamanoi

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Gordon B Mills

http://www.w3.org/2001/XMLSchema#string

Jianjun Shen

http://www.w3.org/2001/XMLSchema#string

Jinhee Kim

http://www.w3.org/2001/XMLSchema#string

John D Short

http://www.w3.org/2001/XMLSchema#string

Kevin D Houston

http://www.w3.org/2001/XMLSchema#string

Ruhee Dere

http://www.w3.org/2001/XMLSchema#string

P2860

Role of AMP-activated protein kinase in mechanism of metformin action

Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

TSC2 mediates cellular energy response to control cell growth and survival

Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth

The AMP-activated protein kinase cascade--a unifying system for energy control

The LKB1 tumor suppressor negatively regulates mTOR signaling

Tuberin binds p27 and negatively regulates its interaction with the SCF component Skp2

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background

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6496-6506

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scholarly article

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10.1158/0008-5472.CAN-07-5756

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P433

16

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68

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2008-08-01T00:00:00Z

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18701472

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3011867

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