Differential regulation of β2 -adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle.
about
The inotropic effect of the active metabolite of levosimendan, OR-1896, is mediated through inhibition of PDE3 in rat ventricular myocardiumAgents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle.β-Adrenergic receptor stimulation increases surface NKCC2 expression in rat thick ascending limbs in a process inhibited by phosphodiesterase 4.Noninvasive stratification of postinfarction rats based on the degree of cardiac dysfunction using magnetic resonance imaging and echocardiography.Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart.Cardiac PDEs and crosstalk between cAMP and cGMP signalling pathways in the regulation of contractility.
P2860
Differential regulation of β2 -adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Differential regulation of β2 ...... failing rat cardiac ventricle.
@ast
Differential regulation of β2 ...... failing rat cardiac ventricle.
@en
Differential regulation of β2 ...... failing rat cardiac ventricle.
@nl
type
label
Differential regulation of β2 ...... failing rat cardiac ventricle.
@ast
Differential regulation of β2 ...... failing rat cardiac ventricle.
@en
Differential regulation of β2 ...... failing rat cardiac ventricle.
@nl
prefLabel
Differential regulation of β2 ...... failing rat cardiac ventricle.
@ast
Differential regulation of β2 ...... failing rat cardiac ventricle.
@en
Differential regulation of β2 ...... failing rat cardiac ventricle.
@nl
P2093
P2860
P50
P1476
Differential regulation of β2 ...... failing rat cardiac ventricle.
@en
P2093
Faraz Afzal
Finn Olav Levy
Jan-Bjørn Osnes
Lise Román Moltzau
Tor Skomedal
P2860
P356
10.1111/J.1476-5381.2010.00890.X
P407
P577
2011-01-01T00:00:00Z