Escherichia coli dihydrofolate reductase catalyzed proton and hydride transfers: temporal order and the roles of Asp27 and Tyr100.
about
Dihydrofolate reductase as a model for studies of enzyme dynamics and catalysisPerspectives on electrostatics and conformational motions in enzyme catalysisToward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography.Insights into the slow-onset tight-binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2-f] quinazoline-1,3-diamine and its derivatives as novel tight-binding inhibitors.Hydride Transfer in DHFR by Transition Path Sampling, Kinetic Isotope Effects, and Heavy Enzyme StudiesThe Effect of Protein Mass Modulation on Human Dihydrofolate Reductase.Network of remote and local protein dynamics in dihydrofolate reductase catalysisExaminations of the Chemical Step in Enzyme Catalysis.Change in heat capacity accurately predicts vibrational coupling in enzyme catalyzed reactions.Increased substrate affinity in the Escherichia coli L28R dihydrofolate reductase mutant causes trimethoprim resistance.The role of the Met20 loop in the hydride transfer in Escherichia coli dihydrofolate reductase.Modulating Enzyme Activity by Altering Protein Dynamics with Solvent
P2860
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P2860
Escherichia coli dihydrofolate reductase catalyzed proton and hydride transfers: temporal order and the roles of Asp27 and Tyr100.
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Escherichia coli dihydrofolate ...... the roles of Asp27 and Tyr100.
@ast
Escherichia coli dihydrofolate ...... the roles of Asp27 and Tyr100.
@en
Escherichia coli dihydrofolate ...... the roles of Asp27 and Tyr100.
@nl
type
label
Escherichia coli dihydrofolate ...... the roles of Asp27 and Tyr100.
@ast
Escherichia coli dihydrofolate ...... the roles of Asp27 and Tyr100.
@en
Escherichia coli dihydrofolate ...... the roles of Asp27 and Tyr100.
@nl
prefLabel
Escherichia coli dihydrofolate ...... the roles of Asp27 and Tyr100.
@ast
Escherichia coli dihydrofolate ...... the roles of Asp27 and Tyr100.
@en
Escherichia coli dihydrofolate ...... the roles of Asp27 and Tyr100.
@nl
P2093
P2860
P356
P1476
Escherichia coli dihydrofolate ...... the roles of Asp27 and Tyr100.
@en
P2093
Amnon Kohen
C Tony Liu
Joshua P Layfield
Kevin Francis
Stephen J Benkovic
Xinyi Huang
P2860
P304
18231-18236
P356
10.1073/PNAS.1415940111
P407
P577
2014-12-01T00:00:00Z