Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo.
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Two for the Price of One: A Neuroprotective Chaperone Kit within NAD Synthase Protein NMNAT2A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degenerationAbsence of SARM1 rescues development and survival of NMNAT2-deficient axons.Impact of Genetic Reduction of NMNAT2 on Chemotherapy-Induced Losses in Cell Viability In Vitro and Peripheral Neuropathy In VivoNMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.Screening with an NMNAT2-MSD platform identifies small molecules that modulate NMNAT2 levels in cortical neurons.Alternative splicing of Drosophila Nmnat functions as a switch to enhance neuroprotection under stress.Molecular chaperones protect against JNK- and Nmnat-regulated axon degeneration in DrosophilaNMNATs, evolutionarily conserved neuronal maintenance factors.Axonal trafficking of NMNAT2 and its roles in axon growth and survival in vivo.Diversification of NAD biological role: the importance of location.Concepts for regulation of axon integrity by enwrapping glia.Wallerian degeneration: an emerging axon death pathway linking injury and disease.Signaling mechanisms regulating Wallerian degeneration.The NAD+ synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT-2) is a p53 downstream targetMolecular mechanisms in the initiation phase of Wallerian degeneration.Deficiency of nicotinamide mononucleotide adenylyltransferase 3 (nmnat3) causes hemolytic anemia by altering the glycolytic flow in mature erythrocytes.Ubiquitously expressed genes participate in cell-specific functions via alternative promoter usage.The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction.An Atypical SCF-like Ubiquitin Ligase Complex Promotes Wallerian Degeneration through Regulation of Axonal Nmnat2.NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy.Lack of nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2): consequences for mouse bladder development and function.Presymptomatic change in microRNAs modulates Tau pathology.Genome-wide QTL mapping results for regional DXA body composition and bone mineral density traits in pigs
P2860
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P2860
Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo.
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Nicotinamide mononucleotide ad ...... integrity in the mouse embryo.
@ast
Nicotinamide mononucleotide ad ...... integrity in the mouse embryo.
@en
Nicotinamide mononucleotide adenylyltransferase 2
@nl
type
label
Nicotinamide mononucleotide ad ...... integrity in the mouse embryo.
@ast
Nicotinamide mononucleotide ad ...... integrity in the mouse embryo.
@en
Nicotinamide mononucleotide adenylyltransferase 2
@nl
prefLabel
Nicotinamide mononucleotide ad ...... integrity in the mouse embryo.
@ast
Nicotinamide mononucleotide ad ...... integrity in the mouse embryo.
@en
Nicotinamide mononucleotide adenylyltransferase 2
@nl
P2093
P2860
P50
P1433
P1476
Nicotinamide mononucleotide ad ...... integrity in the mouse embryo.
@en
P2093
Carol Miligan
Colin E Bishop
Diego Lorenzetti
Jonathan Gilley
Karl-Erik Andersson
Ronald Oppenheim
P2860
P304
P356
10.1371/JOURNAL.PONE.0047869
P407
P577
2012-10-17T00:00:00Z