about
Differential regulation of B-raf isoforms by phosphorylation and autoinhibitory mechanismsPreponderance of the oncogenic V599E and V599K mutations in B-raf kinase domain is enhanced in melanoma cutaneous/subcutaneous metastasesMEK inhibitors and their potential in the treatment of advanced melanoma: the advantages of combination therapyChronic infection by Leishmania amazonensis mediated through MAPK ERK mechanismsOvarian cancer biomarker discovery based on genomic approachesPyrazolopyridine Inhibitors of B-Raf V600E . Part 1: The Development of Selective, Orally Bioavailable, and Efficacious InhibitorsOptimization of diarylthiazole B-raf inhibitors: identification of a compound endowed with high oral antitumor activity, mitigated hERG inhibition, and low paradoxical effectProfile of tivantinib and its potential in the treatment of hepatocellular carcinoma: the evidence to datePseudorabies virus tegument protein Us2 recruits the mitogen-activated protein kinase extracellular-regulated kinase (ERK) to membranes through interaction with the ERK common docking domain.Identification of a novel human kinase supporter of Ras (hKSR-2) that functions as a negative regulator of Cot (Tpl2) signalingB-Raf and Raf-1 are regulated by distinct autoregulatory mechanismsRASSF1A and NORE1A methylation and BRAFV600E mutations in thyroid tumorsB-raf alternative splicing is dispensable for development but required for learning and memory associated with the hippocampus in the adult mouseVanishin is a novel ubiquitinylated death-effector domain protein that blocks ERK activationERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functionsSingle-molecule force measurement via optical tweezers reveals different kinetic features of two BRaf mutants responsible for cardio-facial-cutaneous (CFC) syndromeAdvanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-ERK1/2 MAP kinase signaling pathwayIntegrin-mediated mechanotransduction pathway of low-intensity continuous ultrasound in human chondrocytesMechanistic basis and functional roles of long-term plasticity in auditory neurons induced by a brain-generated estrogen.Localization of ERK/MAP kinase is regulated by the alphaherpesvirus tegument protein Us2A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma.Propofol induces MAPK/ERK cascade dependant expression of cFos and Egr-1 in rat hippocampal slicesPrognostic and Clinicopathologic Associations of BRAF Mutation in Primary Acral Lentiginous Melanoma in Korean Patients: A Preliminary Study.RAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma.Activation of the TLR1/2 pathway induces the shaping of the immune response status of peripheral blood leukocytes.Autoantibodies to BRAF, a new family of autoantibodies associated with rheumatoid arthritisThyroid cancer: current molecular perspectives.New insights into the diagnosis of nodular goiter.Inhibition of IGF-1 receptor kinase blocks the differentiation into cardiomyocyte-like cells of BMSCs induced by IGF-1Flavonoids, Thyroid Iodide Uptake and Thyroid Cancer-A Review.Estrogens and the pathophysiology of the biliary treeSOX2 expression is regulated by BRAF and contributes to poor patient prognosis in colorectal cancerBRAF mutations, microsatellite instability status and cyclin D1 expression predict metastatic colorectal patients' outcome.Malignant melanoma arising from a perianal fistula and harbouring a BRAF gene mutation: a case report.PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers.Distinct molecular features of different macroscopic subtypes of colorectal neoplasmsSerrated neoplasia of the colorectum.Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas.Schwann cell dedifferentiation is independent of mitogenic signaling and uncoupled to proliferation: role of cAMP and JNK in the maintenance of the differentiated stateThe structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal map kinase signaling.
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The Raf/MEK/ERK pathway: new concepts of activation.
@ast
The Raf/MEK/ERK pathway: new concepts of activation.
@en
The Raf/MEK/ERK pathway: new concepts of activation.
@nl
type
label
The Raf/MEK/ERK pathway: new concepts of activation.
@ast
The Raf/MEK/ERK pathway: new concepts of activation.
@en
The Raf/MEK/ERK pathway: new concepts of activation.
@nl
prefLabel
The Raf/MEK/ERK pathway: new concepts of activation.
@ast
The Raf/MEK/ERK pathway: new concepts of activation.
@en
The Raf/MEK/ERK pathway: new concepts of activation.
@nl
P1433
P1476
The Raf/MEK/ERK pathway: new concepts of activation
@en
P2093
C Peyssonnaux
P356
10.1016/S0248-4900(01)01125-X
P577
2001-09-01T00:00:00Z