about
Phosphorylation of MafA is essential for its transcriptional and biological propertiesB-raf alternative splicing is dispensable for development but required for learning and memory associated with the hippocampus in the adult mouseB-Raf and C-Raf are required for melanocyte stem cell self-maintenanceStimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cellsGSK-3-mediated phosphorylation enhances Maf-transforming activityModulation of kinase activity and oncogenic properties by alternative splicing reveals a novel regulatory mechanism for B-RafRAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma.The p42/p44 mitogen-activated protein kinase activation triggers p27Kip1 degradation independently of CDK2/cyclin E in NIH 3T3 cells.Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathwaysThe Raf/MEK/ERK pathway: new concepts of activation.Alternative splicing in oncogenic kinases: from physiological functions to cancerOccurrence of alternatively spliced leader-delta onc-poly(A) transcripts in chicken neuroretina cells infected with Rous-associated virus type 1: implication in transduction of the c-mil/c-raf and c-Rmil/B-raf oncogenesThe mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression.Common mechanism of retrovirus activation and transduction of c-mil and c-Rmil in chicken neuroretina cells infected with Rous-associated virus type 1.A new MAFia in cancer.A Raf-1 mutant that dissociates MEK/extracellular signal-regulated kinase activation from malignant transformation and differentiation but not proliferation.Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytesGSK3-mediated MAF phosphorylation in multiple myeloma as a potential therapeutic targetMB-09AGGRESSIVE MEDULLOBLASTOMA SUBVERTS THE PHOTORECEPTOR SPECIFIC TRANSCRIPTION FACTOR NRL.NRAS-driven melanoma: A RAF can hide another.BRAF as a melanoma susceptibility candidate gene?Chromosomal assignment of two human B-raf(Rmil) proto-oncogene loci: B-raf-1 encoding the p94Braf/Rmil and B-raf-2, a processed pseudogene.MafA transcription factor identifies the early ret-expressing sensory neurons.Comparison of maf gene expression patterns during chick embryo development.NRL and CRX Define Photoreceptor Identity and Reveal Subgroup-Specific Dependencies in Medulloblastoma.Cell context reveals a dual role for Maf in oncogenesis.PFKFB4 controls embryonic patterning via Akt signalling independently of glycolysis.Translational control of tumor immune escape via the eIF4F-STAT1-PD-L1 axis in melanomaMutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathwayActivation of ERK, controlled by Rac1 and Cdc42 via Akt, is required for anoikisSkin tumors induced by sorafenib; paradoxic RAS-RAF pathway activation and oncogenic mutations of HRAS, TP53, and TGFBR1An autocrine ActivinB mechanism drives TGFβ/Activin signaling in Group 3 medulloblastoma
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P50
description
Forscher
@de
chercheur
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investigador
@es
researcher
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ricercatore
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研究者
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name
Alain Eychène
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Eychène A
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Eychène A
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Eychène A
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type
label
Alain Eychène
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Eychène A
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Eychène A
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Eychène A
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altLabel
Eychène A
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prefLabel
Alain Eychène
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Eychène A
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Eychène A
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Eychène A
@nl
P31
P496
0000-0002-6818-7225