Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions - Wikidata - awgldk - TriplyDB

Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions

Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions

http://www.wikidata.org/entity/Q24337629

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Blockade of adenosine A2B receptors ameliorates murine colitis.Emerging role of cystic fibrosis transmembrane conductance regulator - an epithelial chloride channel in gastrointestinal cancers Regulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factors Role of the autotaxin-lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy Structural insights into PDZ-mediated interaction of NHERF2 and LPA2, a cellular event implicated in CFTR channel regulation LPA stimulates intestinal DRA gene transcription via LPA2 receptor, PI3K/AKT, and c-Fos-dependent pathway Lysophosphatidic acid 5 receptor induces activation of Na(+)/H(+) exchanger 3 via apical epidermal growth factor receptor in intestinal epithelial cells Distinct phospholipase C-β isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostasis and wound closure.Functional regulation of cystic fibrosis transmembrane conductance regulator-containing macromolecular complexes: a small-molecule inhibitor approach Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.Clinical and molecular characterization of S1118F-CFTR.Compartmentalized cyclic adenosine 3',5'-monophosphate at the plasma membrane clusters PDE3A and cystic fibrosis transmembrane conductance regulator into microdomains.Lysophosphatidic acid (LPA) receptors: signaling properties and disease relevance.Tobacco carcinogen NNK transporter MRP2 regulates CFTR function in lung epithelia: implications for lung cancer Colorectal cancer cells - Proliferation, survival and invasion by lysophosphatidic acid.Lysophosphatidic acid stimulates the intestinal brush border Na(+)/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF2.CFTR chloride channel in the apical compartments: spatiotemporal coupling to its interacting partners.The PDZ protein GIPC regulates trafficking of the LPA1 receptor from APPL signaling endosomes and attenuates the cell's response to LPA.TRIP6: an adaptor protein that regulates cell motility, antiapoptotic signaling and transcriptional activity.Analysis of CFTR interactome in the macromolecular complexes.Diverse roles of LPA signaling in the intestinal epithelium.Mitigation of the hematopoietic and gastrointestinal acute radiation syndrome by octadecenyl thiophosphate, a small molecule mimic of lysophosphatidic acid PKA and actin play critical roles as downstream effectors in MRP4-mediated regulation of fibroblast migration.A tannic acid-based medical food, Cesinex(®), exhibits broad-spectrum antidiarrheal properties: a mechanistic and clinical study A chemokine receptor CXCR2 macromolecular complex regulates neutrophil functions in inflammatory diseases Regulation of NHE3 by lysophosphatidic acid is mediated by phosphorylation of NHE3 by RSK2.Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides CFTR-SLC26 transporter interactions in epithelia.The lysophosphatidic acid type 2 receptor is required for protection against radiation-induced intestinal injury.The lysophosphatidic acid 2 receptor mediates down-regulation of Siva-1 to promote cell survival.Virtual screening for LPA2-specific agonists identifies a nonlipid compound with antiapoptotic actions.A novel nutrient sensing mechanism underlies substrate-induced regulation of monocarboxylate transporter-1 Secretory diarrhoea: mechanisms and emerging therapies.CXCR2 macromolecular complex in pancreatic cancer: a potential therapeutic target in tumor growth Local modulation of cystic fibrosis conductance regulator: cytoskeleton and compartmentalized cAMP signalling.MAST205 competes with cystic fibrosis transmembrane conductance regulator (CFTR)-associated ligand for binding to CFTR to regulate CFTR-mediated fluid transport Regulation of the LPA2 receptor signaling through the carboxyl-terminal tail-mediated protein-protein interactions Thiazolidinone CFTR inhibitors with improved water solubility identified by structure-activity analysis Compartmentalization of cyclic nucleotide signaling: a question of when, where, and why?Lysophosphatidic acid 2 receptor-mediated supramolecular complex formation regulates its antiapoptotic effect

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Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions

http://www.wikidata.org/entity/Q24337629

description

2005 nî lūn-bûn

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2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年论文

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Journal of Experimental Medicine

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Anjaparavanda P Naren

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Anke Di

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Chunying Li

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Deborah J Nelson

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Erica L Harris

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Gabor J Tigyi

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John S Jackson

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Keanna S Dandridge

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Kevin L Marrs

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Koushik Roy

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P2860

Cystic fibrosis heterozygote resistance to cholera toxin in the cystic fibrosis mouse model

NHERF2 specifically interacts with LPA2 receptor and defines the specificity and efficiency of receptor-mediated phospholipase C-beta3 activation

SS-56, a novel cellular target of autoantibody responses in Sjögren syndrome and systemic lupus erythematosus

The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000.

Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors

The emerging role of lysophosphatidic acid in cancer

PDZ domains: structural modules for protein complex assembly

Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6

Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate

Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

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975-86

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10.1084/JEM.20050421

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7

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202

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16203867

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Afọ ọsịsa

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