SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.
about
Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3betaDAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expressionTRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4.The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repressionDAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cellsRole of Nuclear Receptors in Central Nervous System Development and Associated DiseasesCrosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipidsTranscription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase geneTwo initiator-like elements are required for the combined activation of the human apolipoprotein C-III promoter by upstream stimulatory factor and hepatic nuclear factor-4A point mutation of the AF2 transactivation domain of the glucocorticoid receptor disrupts its interaction with steroid receptor coactivator 1Conserved amino acids within CCAAT enhancer-binding proteins (C/EBP(alpha) and beta) regulate phosphoenolpyruvate carboxykinase (PEPCK) gene expressionIn vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping.Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasisLXXLL peptide converts transportan 10 to a potent inducer of apoptosis in breast cancer cells.Inhibitor of the tissue-specific transcription factor HNF4, a potential regulator in early Xenopus development.Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) familyMED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells.Med25 is required for RNA polymerase II recruitment to specific promoters, thus regulating xenobiotic and lipid metabolism in human liver.Nuclear hormone receptors in nematodes: evolution and functionReceptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.Two functional modes of a nuclear receptor-recruited arginine methyltransferase in transcriptional activation.The function of steroid receptor coactivator-1 in normal tissues and cancerIn pursuit of genes of glucose metabolismModulation of hepatocyte nuclear factor-4alpha function by the peroxisome-proliferator-activated receptor-gamma co-activator-1alpha in the acute-phase response.Liver-specific hepatocyte nuclear factor-4alpha deficiency: greater impact on gene expression in male than in female mouse liver.The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivatorCell signaling and nuclear receptors: new opportunities for molecular pharmaceuticals in liver disease.Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies.Role of accessory factors and steroid receptor coactivator 1 in the regulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids.Functional properties of the R154X HNF-4alpha protein generated by a mutation associated with maturity-onset diabetes of the young, type 1.Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays.Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism.A thyroid hormone response unit formed between the promoter and first intron of the carnitine palmitoyltransferase-Ialpha gene mediates the liver-specific induction by thyroid hormone.Role of hepatocyte nuclear factor 4α (HNF4α) in cell proliferation and cancer.Regulation of hepatocyte identity and quiescence.Transcriptional activation by hepatocyte nuclear factor-4 in a cell-free system derived from rat liver nucleiThe role of microRNAs in hepatocyte nuclear factor-4alpha expression and transactivation.Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4alpha1.Competitive cofactor recruitment by orphan receptor hepatocyte nuclear factor 4alpha1: modulation by the F domain.Critical role of charged residues in helix 7 of the ligand binding domain in Hepatocyte Nuclear Factor 4alpha dimerisation and transcriptional activity.
P2860
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P2860
SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.
description
1998 nî lūn-bûn
@nan
1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.
@ast
SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.
@en
SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.
@nl
type
label
SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.
@ast
SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.
@en
SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.
@nl
prefLabel
SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.
@ast
SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.
@en
SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.
@nl
P2860
P356
P1476
SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.
@en
P2093
Daryl K Granner
John M Stafford
P2860
P304
30847-30850
P356
10.1074/JBC.273.47.30847
P407
P577
1998-11-01T00:00:00Z