Expression of full-length utrophin prevents muscular dystrophy in mdx mice.
about
Molecular and cell-based therapies for muscle degenerations: a road under constructionHuman cytomegalovirus IE1 promoter/enhancer drives variable gene expression in all fiber types in transgenic mouse skeletal muscleThe potential of sarcospan in adhesion complex replacement therapeutics for the treatment of muscular dystrophyStem cells for skeletal muscle regeneration: therapeutic potential and roadblocksPerspectives of stem cell therapy in Duchenne muscular dystrophyRescue of dystrophic skeletal muscle by PGC-1α involves a fast to slow fiber type shift in the mdx mouseMuscle-specific SIRT1 gain-of-function increases slow-twitch fibers and ameliorates pathophysiology in a mouse model of duchenne muscular dystrophyCurrent understanding of molecular pathology and treatment of cardiomyopathy in duchenne muscular dystrophyAnimal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapyThe dystrophin complex forms a mechanically strong link between the sarcolemma and costameric actinUtrophin up-regulation by an artificial transcription factor in transgenic miceIRES-mediated translation of utrophin A is enhanced by glucocorticoid treatment in skeletal muscle cellsExpression of glycogen phosphorylase isoforms in cultured muscle from patients with McArdle's disease carrying the p.R771PfsX33 PYGM mutationDrug discovery for Duchenne muscular dystrophy via utrophin promoter activation screeningDaily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouseExpression of utrophin A mRNA correlates with the oxidative capacity of skeletal muscle fiber types and is regulated by calcineurin/NFAT signalingLong-Term Quercetin Dietary Enrichment Partially Protects Dystrophic Skeletal MuscleIdentification and characterisation of transcript and protein of a new short N-terminal utrophin isoformThe utrophin actin-binding domain binds F-actin in two different modes: implications for the spectrin superfamily of proteins.The Dystrophin Complex: Structure, Function, and Implications for TherapyMicroutrophin delivery through rAAV6 increases lifespan and improves muscle function in dystrophic dystrophin/utrophin-deficient miceInteraction of dystrophin rod domain with membrane phospholipids. Evidence of a close proximity between tryptophan residues and lipids.Metabolic profiles to define the genome: can we hear the phenotypes?Use of imaging biomarkers to assess perfusion and glucose metabolism in the skeletal muscle of dystrophic mice.Ets-2 repressor factor silences extrasynaptic utrophin by N-box mediated repression in skeletal muscle.Skeletal muscle-specific ablation of gamma(cyto)-actin does not exacerbate the mdx phenotype.Blastocyst injection of wild type embryonic stem cells induces global corrections in mdx mice.Functional substitution by TAT-utrophin in dystrophin-deficient mice.Arginine metabolism by macrophages promotes cardiac and muscle fibrosis in mdx muscular dystrophy.Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.High levels of sarcospan are well tolerated and act as a sarcolemmal stabilizer to address skeletal muscle and pulmonary dysfunction in DMD.Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal musclesMuscle structure influences utrophin expression in mdx mice.Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogs.Utrophin binds laterally along actin filaments and can couple costameric actin with sarcolemma when overexpressed in dystrophin-deficient muscle.Emerging genetic therapies to treat Duchenne muscular dystrophyResveratrol induces expression of the slow, oxidative phenotype in mdx mouse muscle together with enhanced activity of the SIRT1-PGC-1α axis.Dystrophin and utrophin: genetic analyses of their role in skeletal muscle.Regulation and functional significance of utrophin expression at the mammalian neuromuscular synapse.Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.
P2860
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P2860
Expression of full-length utrophin prevents muscular dystrophy in mdx mice.
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Expression of full-length utrophin prevents muscular dystrophy in mdx mice.
@ast
Expression of full-length utrophin prevents muscular dystrophy in mdx mice.
@en
Expression of full-length utrophin prevents muscular dystrophy in mdx mice.
@nl
type
label
Expression of full-length utrophin prevents muscular dystrophy in mdx mice.
@ast
Expression of full-length utrophin prevents muscular dystrophy in mdx mice.
@en
Expression of full-length utrophin prevents muscular dystrophy in mdx mice.
@nl
prefLabel
Expression of full-length utrophin prevents muscular dystrophy in mdx mice.
@ast
Expression of full-length utrophin prevents muscular dystrophy in mdx mice.
@en
Expression of full-length utrophin prevents muscular dystrophy in mdx mice.
@nl
P2093
P356
P1433
P1476
Expression of full-length utrophin prevents muscular dystrophy in mdx mice.
@en
P2093
Deconinck N
P2888
P304
P356
10.1038/4033
P407
P577
1998-12-01T00:00:00Z
P5875
P6179
1009368810