Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy. - Wikidata - awgldk - TriplyDB

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.

http://www.wikidata.org/entity/Q33589972

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The effects of testosterone deprivation and supplementation on proteasomal and autophagy activity in the skeletal muscle of the male mouse: differential effects on high-androgen responder and low-androgen responder muscle groups Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function An emerging role for TOR signaling in mammalian tissue and stem cell physiology Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine Skeletal muscle autophagy: a new metabolic regulator Multifaceted role of insulin-like growth factors and mammalian target of rapamycin in skeletal muscle Cellular and molecular mechanisms of muscle atrophy Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth The catalytic subunit of the system L1 amino acid transporter (slc7a5) facilitates nutrient signalling in mouse skeletal muscle From Nutrient to MicroRNA: a Novel Insight into Cell Signaling Involved in Skeletal Muscle Development and Disease Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake mTOR signaling in tumorigenesis The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging Reversal of muscle atrophy by Zhimu-Huangbai herb-pair via Akt/mTOR/FoxO3 signal pathway in streptozotocin-induced diabetic mice Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice Skeletal muscle dysfunction in muscle-specific LKB1 knockout mice.Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury.Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production.Systems-based discovery of tomatidine as a natural small molecule inhibitor of skeletal muscle atrophy.Cachectic skeletal muscle response to a novel bout of low-frequency stimulation Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue.Absence of γ-sarcoglycan alters the response of p70S6 kinase to mechanical perturbation in murine skeletal muscle.Rag GTPases are cardioprotective by regulating lysosomal function.The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells.Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice.Impaired adaptive response to mechanical overloading in dystrophic skeletal muscle Predicting the fission yeast protein interaction network.Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous mice.mTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis.Oxidative damage induced by cigarette smoke exposure in mice: impact on lung tissue and diaphragm muscle microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells.IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation.REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1: responses to aging, immobilization, and remobilization.Regulation of mTOR activity in Snell dwarf and GH receptor gene-disrupted mice.Mtor-Fanconi Anemia DNA Damage Repair Pathway in Cancer.Histone deacetylase 6 is a FoxO transcription factor-dependent effector in skeletal muscle atrophy.A role for Galgt1 in skeletal muscle regeneration.Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models.Branched-chain amino acids, mitochondrial biogenesis, and healthspan: an evolutionary perspective.

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P2860

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.

http://www.wikidata.org/entity/Q33589972

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

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2009年論文

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2009年论文

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name

Muscle inactivation of mTOR ca ...... ts leading to severe myopathy.

@ast

Muscle inactivation of mTOR ca ...... ts leading to severe myopathy.

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Muscle inactivation of mTOR ca ...... ts leading to severe myopathy.

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type

label

Muscle inactivation of mTOR ca ...... ts leading to severe myopathy.

@ast

Muscle inactivation of mTOR ca ...... ts leading to severe myopathy.

@en

Muscle inactivation of mTOR ca ...... ts leading to severe myopathy.

@nl

prefLabel

Muscle inactivation of mTOR ca ...... ts leading to severe myopathy.

@ast

Muscle inactivation of mTOR ca ...... ts leading to severe myopathy.

@en

Muscle inactivation of mTOR ca ...... ts leading to severe myopathy.

@nl

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Journal of Cell Biology

P1476

Muscle inactivation of mTOR ca ...... ts leading to severe myopathy.

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P2093

Agnès Conjard-Duplany

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Alban Vignaud

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Arnaud Ferry

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Bernard Ferrier

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Claudine Corneloup

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Damien Freyssenet

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Daniel Hantaï

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Dominique Baas

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Hervé Sanchez

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Hélène Richard-Bulteau

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P2860

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

TOR signaling in growth and metabolism

Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian cells

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

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859-874

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10.1083/JCB.200903131

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6

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187

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Stéphanie Bauché

Yann-Gaël Gangloff

Jean-François Tanti

Valérie Risson

Aurélia Defour

Vincent Moncollin

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2009-12-01T00:00:00Z

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40686298

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20008564

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2806319

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