Identification of amino acids in the human tetherin transmembrane domain responsible for HIV-1 Vpu interaction and susceptibility.
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HIV-1 Vpu protein antagonizes innate restriction factor BST-2 via lipid-embedded helix-helix interactionsStructural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1The restriction factors of human immunodeficiency virusAntiviral inhibition of enveloped virus release by tetherin/BST-2: action and counteractionExpression of HIV-1 Vpu leads to loss of the viral restriction factor CD317/Tetherin from lipid rafts and its enhanced lysosomal degradationMechanism of HIV-1 virion entrapment by tetherinCharacterization of red-capped mangabey tetherin: implication for the co-evolution of primates and their lentivirusesCounteraction of the multifunctional restriction factor tetherinCounteraction of tetherin antiviral activity by two closely related SIVs differing by the presence of a Vpu geneVpu and BST2: Still Not There Yet?Pandemic HIV-1 Vpu overcomes intrinsic herd immunity mediated by tetherin.Efficient Vpu-Mediated Tetherin Antagonism by an HIV-1 Group O Strain.Modulation of HIV-1-host interaction: role of the Vpu accessory proteinAnalysis of the human immunodeficiency virus type 1 M group Vpu domains involved in antagonizing tetherin.Eastern chimpanzees, but not bonobos, represent a simian immunodeficiency virus reservoir.Human tetherin exerts strong selection pressure on the HIV-1 group N Vpu protein.The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu functionQuantification of deaminase activity-dependent and -independent restriction of HIV-1 replication mediated by APOBEC3F and APOBEC3G through experimental-mathematical investigation.Simian-Human immunodeficiency viruses expressing chimeric subtype B/C Vpu proteins demonstrate the importance of the amino terminal and transmembrane domains in the rate of CD4(+) T cell loss in macaques.A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction.Vpu downmodulates two distinct targets, tetherin and gibbon ape leukemia virus envelope, through shared features in the Vpu cytoplasmic tail.Vpu binds directly to tetherin and displaces it from nascent virions.Identification of Residues in the BST-2 TM Domain Important for Antagonism by HIV-1 Vpu Using a Gain-of-Function Approach.Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence.In COS cells Vpu can both stabilize tetherin expression and counteract its antiviral activity.Some human immunodeficiency virus type 1 Vpu proteins are able to antagonize macaque BST-2 in vitro and in vivo: Vpu-negative simian-human immunodeficiency viruses are attenuated in vivo.Separable determinants of subcellular localization and interaction account for the inability of group O HIV-1 Vpu to counteract tetherinMembrane Anchoring by a C-terminal Tryptophan Enables HIV-1 Vpu to Displace Bone Marrow Stromal Antigen 2 (BST2) from Sites of Viral AssemblyStructural Basis for the Antiviral Activity of BST-2/Tetherin and Its Viral AntagonismVpu augments the initial burst phase of HIV-1 propagation and downregulates BST2 and CD4 in humanized mice.Experimental evaluation of the zoonotic infection potency of simian retrovirus type 4 using humanized mouse model.Molecular dynamics simulation in virus research.Coevolutionary dynamics between tribe Cercopithecini tetherins and their lentiviruses.Increased BST2 expression during simian immunodeficiency virus infection is not a determinant of disease progression in rhesus monkeysA small molecule compound IMB-LA inhibits HIV-1 infection by preventing viral Vpu from antagonizing the host restriction factor BST-2.The size and conservation of a coiled-coil structure in the ectodomain of human BST-2/tetherin is dispensable for inhibition of HIV-1 virion release.Host restriction factors in retroviral infection: promises in virus-host interaction.Filamin A Is Involved in HIV-1 Vpu-mediated Evasion of Host Restriction by Modulating Tetherin Expression.Down-modulation of primate lentiviral receptors by Nef proteins of simian immunodeficiency virus (SIV) of chimpanzees (SIVcpz) and related SIVs: implication for the evolutionary event at the emergence of SIVcpz.Functional antagonism of rhesus macaque and chimpanzee BST-2 by HIV-1 Vpu is mediated by cytoplasmic domain interactions.
P2860
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P2860
Identification of amino acids in the human tetherin transmembrane domain responsible for HIV-1 Vpu interaction and susceptibility.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Identification of amino acids ...... nteraction and susceptibility.
@ast
Identification of amino acids ...... nteraction and susceptibility.
@en
Identification of amino acids ...... nteraction and susceptibility.
@nl
type
label
Identification of amino acids ...... nteraction and susceptibility.
@ast
Identification of amino acids ...... nteraction and susceptibility.
@en
Identification of amino acids ...... nteraction and susceptibility.
@nl
prefLabel
Identification of amino acids ...... nteraction and susceptibility.
@ast
Identification of amino acids ...... nteraction and susceptibility.
@en
Identification of amino acids ...... nteraction and susceptibility.
@nl
P2093
P2860
P356
P1433
P1476
Identification of amino acids ...... nteraction and susceptibility.
@en
P2093
Hironori Sato
Hirotaka Ebina
Hirotaka Ode
Klaus Strebel
Seiji P Yamamoto
Takeshi Yoshida
Tomoko Kobayashi
Yoshio Koyanagi
P2860
P304
P356
10.1128/JVI.01668-10
P407
P577
2010-11-10T00:00:00Z