A domain of human immunodeficiency virus type 1 Vpr containing repeated H(S/F)RIG amino acid motifs causes cell growth arrest and structural defects.
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The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition poreHuman immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) interacts with Lys-tRNA synthetase: implications for priming of HIV-1 reverse transcription.Human immunodeficiency virus type 1 Vpr-mediated G(2) cell cycle arrest: Vpr interferes with cell cycle signaling cascades by interacting with the B subunit of serine/threonine protein phosphatase 2AInduction of the Tat-binding protein 1 gene accompanies the disabling of oncogenic erbB receptor tyrosine kinasesHuman immunodeficiency virus type 1 Vpr interacts with HHR23A, a cellular protein implicated in nucleotide excision DNA repairControl of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2Human immunodeficiency virus type 1 Vpr induces G2 checkpoint activation by interacting with the splicing factor SAP145Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosisHIV-1 Vpr interacts with a human 34-kDa mov34 homologue, a cellular factor linked to the G2/M phase transition of the mammalian cell cycleHuman immunodeficiency virus type 1 Vpr protein binds to the uracil DNA glycosylase DNA repair enzymeHIV-1 rev depolymerizes microtubules to form stable bilayered ringsHuman immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin BAnalysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiaeNMR structure of the (1-51) N-terminal domain of the HIV-1 regulatory protein VprSmall heat shock protein suppression of Vpr-induced cytoskeletal defects in budding yeast.Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivoHIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase.Pathogenesis of HIV-1 infection within bone marrow cells.Mutational analysis of Vpr-induced G2 arrest, nuclear localization, and cell death in fission yeast.Molecular Mechanisms of Neurodegenerative Diseases Induced by Human Retroviruses: A Review.Maintenance of an intact human immunodeficiency virus type 1 vpr gene following mother-to-infant transmissionFunctional role of residues corresponding to helical domain II (amino acids 35 to 46) of human immunodeficiency virus type 1 Vpr.Vipirinin, a coumarin-based HIV-1 Vpr inhibitor, interacts with a hydrophobic region of VPR.Functional analysis of the simian immunodeficiency virus Vpx protein: identification of packaging determinants and a novel nuclear targeting domain.Microbial pathogens and apoptotic anticancer therapy.The host-pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domainsA leucine triplet repeat sequence (LXX)4 in p6gag is important for Vpr incorporation into human immunodeficiency virus type 1 particlesNuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr.The vertical transmission of human immunodeficiency virus type 1: molecular and biological properties of the virus.HIV-1 viral protein R (Vpr) and its interactions with host cellHuman immunodeficiency virus viral protein R as an extracellular protein in neuropathogenesis.The HIV-derived protein Vpr52-96 has anti-glioma activity in vitro and in vivo.Genetic selection of peptide inhibitors of human immunodeficiency virus type 1 Vpr.The HIV-1 Vpr Protein: A Multifaceted Target for Therapeutic Intervention.Efficient DNA transfection mediated by the C-terminal domain of human immunodeficiency virus type 1 viral protein RPhosphorylation of human immunodeficiency virus type 1 Vpr regulates cell cycle arrestModulation of the cell division cycle by human papillomavirus type 18 E4.The first HxRxG motif in simian immunodeficiency virus mac239 Vpr is crucial for G(2)/M cell cycle arrest.Activation of JNK-dependent pathway is required for HIV viral protein R-induced apoptosis in human monocytic cells: involvement of antiapoptotic BCL2 and c-IAP1 genes.Fumagillin suppresses HIV-1 infection of macrophages through the inhibition of Vpr activity.
P2860
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P2860
A domain of human immunodeficiency virus type 1 Vpr containing repeated H(S/F)RIG amino acid motifs causes cell growth arrest and structural defects.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մարտին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A domain of human immunodeficiency virus type 1 Vpr containing repeated H
@nl
A domain of human immunodefici ...... arrest and structural defects.
@ast
A domain of human immunodefici ...... arrest and structural defects.
@en
type
label
A domain of human immunodeficiency virus type 1 Vpr containing repeated H
@nl
A domain of human immunodefici ...... arrest and structural defects.
@ast
A domain of human immunodefici ...... arrest and structural defects.
@en
prefLabel
A domain of human immunodeficiency virus type 1 Vpr containing repeated H
@nl
A domain of human immunodefici ...... arrest and structural defects.
@ast
A domain of human immunodefici ...... arrest and structural defects.
@en
P2093
P2860
P356
P1476
A domain of human immunodefici ...... arrest and structural defects
@en
P2093
A Kirkpatrick
D R Hewish
L A Castelli
P2860
P304
P356
10.1073/PNAS.92.7.2770
P407
P577
1995-03-01T00:00:00Z