Human immunodeficiency virus type 1 Vpr protein binds to the uracil DNA glycosylase DNA repair enzyme
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The HIV1 protein Vpr acts to enhance constitutive DCAF1-dependent UNG2 turnoverThe Vpr protein from HIV-1: distinct roles along the viral life cycleHuman immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) interacts with Lys-tRNA synthetase: implications for priming of HIV-1 reverse transcription.Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functionsHuman immunodeficiency virus type 1 Vpr induces the degradation of the UNG and SMUG uracil-DNA glycosylasesInvolvement of rhp23, a Schizosaccharomyces pombe homolog of the human HHR23A and Saccharomyces cerevisiae RAD23 nucleotide excision repair genes, in cell cycle control and protein ubiquitinationHuman immunodeficiency virus type 1 Vpr interacts with HHR23A, a cellular protein implicated in nucleotide excision DNA repairLatency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus recruits uracil DNA glycosylase 2 at the terminal repeats and is important for latent persistence of the virusUracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrestHuman immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustardHIV-1 Vpr interacts with a human 34-kDa mov34 homologue, a cellular factor linked to the G2/M phase transition of the mammalian cell cycleAnalysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiaeHuman cytomegalovirus uracil DNA glycosylase associates with ppUL44 and accelerates the accumulation of viral DNA.dUTPase: the frequently overlooked enzyme encoded by many retrovirusesThe DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destructionSmall heat shock protein suppression of Vpr-induced cytoskeletal defects in budding yeast.Cullin4A and cullin4B are interchangeable for HIV Vpr and Vpx action through the CRL4 ubiquitin ligase complexInfluence of reverse transcriptase variants, drugs, and Vpr on human immunodeficiency virus type 1 mutant frequencies.Human immunodeficiency virus type 1 Vpr interacts with antiapoptotic mitochondrial protein HAX-1Primate lentiviral Vpx commandeers DDB1 to counteract a macrophage restriction.The TCL1A oncoprotein interacts directly with the NF-kappaB inhibitor IkappaB.Mutational analysis of Vpr-induced G2 arrest, nuclear localization, and cell death in fission yeast.Feline immunodeficiency virus (FIV) as a model for study of lentivirus infections: parallels with HIV.Functional role of residues corresponding to helical domain II (amino acids 35 to 46) of human immunodeficiency virus type 1 Vpr.The interaction of vpr with uracil DNA glycosylase modulates the human immunodeficiency virus type 1 In vivo mutation rate.Human immunodeficiency virus and AIDS: insights from animal lentivirusesHuman immunodeficiency virus type 1 Vpr protein is incorporated into the virion in significantly smaller amounts than gag and is phosphorylated in infected cellsA conserved dileucine-containing motif in p6(gag) governs the particle association of Vpx and Vpr of simian immunodeficiency viruses SIV(mac) and SIV(agm)Vpr-host interactions during HIV-1 viral life cycle.The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase.X4 and R5 HIV-1 have distinct post-entry requirements for uracil DNA glycosylase during infection of primary cells.HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation.Using death to one's advantage: HIV modulation of apoptosis.Phages and HIV-1: from display to interplay.The (52-96) C-terminal domain of Vpr stimulates HIV-1 IN-mediated homologous strand transfer of mini-viral DNA.Abundant non-canonical dUTP found in primary human macrophages drives its frequent incorporation by HIV-1 reverse transcriptase.Cellular phenotype impacts human immunodeficiency virus type 1 viral protein R subcellular localizationReplication properties of dUTPase-deficient mutants of caprine and ovine lentivirusesdUTPase-minus caprine arthritis-encephalitis virus is attenuated for pathogenesis and accumulates G-to-A substitutions.Vpr of simian immunodeficiency virus of African green monkeys is required for replication in macaque macrophages and lymphocytes.
P2860
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P2860
Human immunodeficiency virus type 1 Vpr protein binds to the uracil DNA glycosylase DNA repair enzyme
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Human immunodeficiency virus t ...... glycosylase DNA repair enzyme
@ast
Human immunodeficiency virus t ...... glycosylase DNA repair enzyme
@en
Human immunodeficiency virus t ...... glycosylase DNA repair enzyme
@nl
type
label
Human immunodeficiency virus t ...... glycosylase DNA repair enzyme
@ast
Human immunodeficiency virus t ...... glycosylase DNA repair enzyme
@en
Human immunodeficiency virus t ...... glycosylase DNA repair enzyme
@nl
prefLabel
Human immunodeficiency virus t ...... glycosylase DNA repair enzyme
@ast
Human immunodeficiency virus t ...... glycosylase DNA repair enzyme
@en
Human immunodeficiency virus t ...... glycosylase DNA repair enzyme
@nl
P2093
P2860
P3181
P1433
P1476
Human immunodeficiency virus t ...... glycosylase DNA repair enzyme
@en
P2093
G Slupphaug
I Agostini
J M Navarro
M Bouhamdan
R Benarous
P2860
P304
P3181
P407
P577
1996-02-01T00:00:00Z