nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.
about
Neutral sphingomyelinase-3 is a DNA damage and nongenotoxic stress-regulated gene that is deregulated in human malignanciesNeutral sphingomyelinase 2 (nSMase2) is a phosphoprotein regulated by calcineurin (PP2B)Trafficking and Functions of Bioactive Sphingolipids: Lessons from Cells and Model MembranesRole of Sphingolipids in the Pathobiology of Lung InflammationCeramide-induced apoptosis in renal tubular cells: a role of mitochondria and sphingosine-1-phoshateNeutral sphingomyelinase 2 is palmitoylated on multiple cysteine residues. Role of palmitoylation in subcellular localizationEarly activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampiTumor necrosis factor-alpha-induced neutral sphingomyelinase-2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors.A novel mitochondrial sphingomyelinase in zebrafish cells.4-Hydroxynonenal Contributes to Angiogenesis through a Redox-Dependent Sphingolipid Pathway: Prevention by Hydralazine Derivatives.Sphingomyelinases: their regulation and roles in cardiovascular pathophysiology.Sphingomyelin metabolism at the plasma membrane: implications for bioactive sphingolipids.Sphingolipids in obesity, type 2 diabetes, and metabolic disease.Genetics of the ceramide/sphingosine-1-phosphate rheostat in blood pressure regulation and hypertension.EGF receptor exposed to oxidative stress acquires abnormal phosphorylation and aberrant activated conformation that impairs canonical dimerizationRoles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis.Lung injury and cancer: Mechanistic insights into ceramide and EGFR signaling under cigarette smoke.Anterograde and retrograde transport of neutral sphingomyelinase-2 between the Golgi and the plasma membrane.Effect of procysteine on aging-associated changes in hepatic GSH and SMase: evidence for transcriptional regulation of smpd3Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.Role for neutral sphingomyelinase-2 in tumor necrosis factor alpha-stimulated expression of vascular cell adhesion molecule-1 (VCAM) and intercellular adhesion molecule-1 (ICAM) in lung epithelial cells: p38 MAPK is an upstream regulator of nSMase2.Neutral sphingomyelinase 2: a novel target in cigarette smoke-induced apoptosis and lung injury.Identification of novel anionic phospholipid binding domains in neutral sphingomyelinase 2 with selective binding preferenceLung cancer and lung injury: the dual role of ceramideProtein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1betaHydrogen peroxide signaling is required for glucocorticoid-induced apoptosis in lymphoma cells.Neutral sphingomyelinase 2 activity and protein stability are modulated by phosphorylation of five conserved serines.Neutral sphingomyelinase-2 is a redox sensitive enzyme: role of catalytic cysteine residues in regulation of enzymatic activity through changes in oligomeric state.Role of ceramides in nonalcoholic fatty liver diseaseCharacterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx MiceOxidative stress kills human primary oligodendrocytes via neutral sphingomyelinase: implications for multiple sclerosis.Expression of ceramide-metabolising enzymes in subcutaneous and intra-abdominal human adipose tissue.Regulation of neutral sphingomyelinase-2 (nSMase2) by tumor necrosis factor-alpha involves protein kinase C-delta in lung epithelial cellsConfluence induced threonine41/serine45 phospho-beta-catenin dephosphorylation via ceramide-mediated activation of PP1cgamma.Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias.Off-target function of the Sonic hedgehog inhibitor cyclopamine in mediating apoptosis via nitric oxide-dependent neutral sphingomyelinase 2/ceramide inductionConverging roles for sphingolipids and cell stress in the progression of neuro-AIDSNeutral sphingomyelinase-2, acid sphingomyelinase, and ceramide levels in COPD patients compared to controlsNeutral sphingomyelinase 2 is activated by cigarette smoke to augment ceramide-induced apoptosis in lung cell death.Ceramide and mitochondria in ischemia/reperfusion.
P2860
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P2860
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.
@ast
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.
@en
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.
@nl
type
label
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.
@ast
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.
@en
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.
@nl
prefLabel
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.
@ast
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.
@en
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.
@nl
P2093
P2860
P1476
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.
@en
P2093
Michal Levy
S Sianna Castillo
Tzipora Goldkorn
P2860
P304
P356
10.1016/J.BBRC.2006.04.013
P407
P577
2006-04-19T00:00:00Z